Doerrier Carolina

News and Events

Working Groups

Short-Term Scientific Missions

Management Committee

Members

COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Doerrier Carolina

MitoPedia topics: EAGLE

COST: Member COST WG1: WG1 COST WG2: WG2 COST WG3: WG3 COST WG4: WG4

COST ECI: ECI

MC Substitute - Management Committee MitoEAGLE

Name	Doerrier Velasco Carolina, PhD.
Institution	Background: ES Granada Acuna-Castroviejo D Carolina was part of the Oroboros Team from October 2014 to May 2022.
Address	,
City	Innsbruck
State/Province
Country	Austria
Email	[email protected]
Weblink	ResearchGate profile, ORCID:, www.bioblast.at
O2k-Network Lab	AT Innsbruck Oroboros, ES Granada Acuna-Castroviejo D

Bioenergetics Communications

Carolina Doerrier is Section Editor of the journal Bioenergetics Communications

Keywords: O2k-FluoRespirometry, oxidative stress, permeabilized muscle fibers, NAD(P)H, sepsis, aging, melatonin

Oroboros-team

Previous laboratory: ES Granada Acuna-Castroviejo D, AT Innsbruck Oroboros.
Collaboration with the Gnaiger Lab in Innsbruck during a 3-months scholarship (Sep - Dec 2011), in the frame of the K-Regio project MitoCom Tyrol.
Collaboration with the Goodpaster Lab in Orlando (2017).
MitoEAGLE Short-Term Scientific Mission at ES Barcelona Garcia-Roves PM in Barcelona (2018).
Guest tutor at IOC65 and IOC68.
Tutor at IOC100, IOC104, IOC106, IOC110, IOC112, IOC114, IOC115, IOC116, IOC120, IOC122, IOC130, IOC132, IOC133, IOC137, IOC139, IOC144 and IOC145.

Bioblast Editorial Board

Bioblast national editor MiPNet Laboratories Spain
Library of protocols

MitoEAGLE Short-Term Scientific Mission

- - - STSM Grant Period 2

Work Plan summary

WORKPLAN SUMMARY Different experimental aspects (e.g. purity of the preparations, environmental humidity which could affect the wet weight of the muscle, chemicals) will be evaluated during the STSM in order to clarify the sources of variability found in the MitoEAGLE WG2 pilot study. The preparation of the samples will be performed according the SOP established for the MitoEAGLE WG2 pilot study. Permeabilized fibers from soleus of C57BL6/J mice will be used. Mitochondrial respiration will be assessed by O2k high-resolution respirometry (HRR). The Substrate- Uncoupler-Inhibitor Titration (SUIT) protocol used in the MitoEAGLE WG2 pilot study for obtaining mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers, will be used to perform the experiments during the STSM at the Department of Physiological Sciences II in the Faculty of Medicine (Barcelona University, Barcelona, Spain).

Participated at

Labels: Field of research: Basic Topics: High-resolution respirometry, Mitochondria, Melatonin, Reactive oxygen species, Reactive nitrogen species, Sepsis

Publications

	Published	Reference
Pallag 2022 Int J Mol Sci	2022	Pallag G, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation supports mitochondrial ATP production when Complex I is inhibited. https://doi.org/10.3390/ijms23095111
Torres-Quesada 2022 Cancers (Basel)	2022	Torres-Quesada O, Doerrier C, Strich S, Gnaiger E, Stefan E (2022) Physiological cell culture media tune mitochondrial bioenergetics and drug sensitivity in cancer cell models. https://doi.org/10.3390/cancers14163917
Cardoso 2021 BEC MgG	2021	Cardoso LHD, Doerrier C, Gnaiger E (2021) Magnesium Green for fluorometric measurement of ATP production does not interfere with mitochondrial respiration. https://doi.org/10.26124/bec:2021-0001
Komlodi 2021 BEC Q	2021	Komlódi T, Cardoso LHD, Doerrier C, Moore AL, Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. https://doi.org/10.26124/bec:2021-0003
MitoEAGLE muscle 1	2020	Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. - Updated: 2020-03-08
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. https://doi.org/10.26124/bec:2020-0001.v1
MitoEAGLE blood cells 1	2020	Åsander Frostner Eleonor, Aburel Oana M, Avram Vlad F, Calabria Elisa, Castelo Rueda Maria Paulina, Chamkha Imen, Čižmárová Beata, Danila Maria-Daniela, Doerrier Carolina, Eckert Gunter P, Ehinger Johannes K, Elmer Eskil, Garcia-Souza Luiz F, Gnaiger Erich, Hoppel Florian, Karabatsiakis Alexander, Keppner Gloria, Kidere Dita, Krako Jakovljević Nina, Labieniec-Watala Magdalena, Lelcu Theia, Micankova Petra, Michalak Slawomir, Molina Anthony JA, Pavlovic Kasja, Pichler Irene, Piel Sarah, Rousar Tomas, Rybacka-Mossakowska Joanna, Schartner Melanie, Siewiera Karolina, Silaidos Carmina, Sjövall Fredrik, Sobotka Ondrej, Sumbalova Zuzana, Swiniuch Daria, Vernerova Andrea, Volani Chiara, Vujacic-Mirski Ksenija, Watala Cezary (2020) Interlaboratory guide to mitochondrial respiratory studies with peripheral blood mononuclear cells and platelets. - Updated: 2020-03-06 - *Confirmed
Doerrier 2019 MitoFit Preprint Arch EA	2019	Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2019) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. https://doi.org/10.26124/mitofit:ea19.MiPSchool.0009
Chabi 2019 MitoFit Preprint Arch EA	2019	Chabi Béatrice, Ost M, Gama-Perez P, Dahdah N, Lemieux H, Holody CD, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Pesta D, Calabria E, Casado M, Fernandez-Ortiz M, Acuña-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wüst R, Dayanidhi S, Gnaiger E, Doerrier C, Garcia-Roves PM (2019) Generating reference values on mitochondrial respiration in permeabilized muscle fibers. https://doi.org/10.26124/mitofit:ea19.MitoEAGLE.0001
Komlodi 2018 Methods Mol Biol	2018	Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. Methods Mol Biol 1782:137-55.
Ost 2018 Curr Opin Clin Nutr Metab Care	2018	Ost M, Doerrier C, Gama-Perez P, Moreno-Gomez S (2018) Analysis of mitochondrial respiratory function in tissue biopsies and blood cells. Curr Opin Clin Nutr Metab Care 21:336-42.
Doerrier 2018 Methods Mol Biol	2018	Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. https://doi.org/10.1007/978-1-4939-7831-1_3
Bernardinelli 2017 PLoS One	2017	Bernardinelli E, Costa R, Scantamburlo G, To J, Morabito R, Nofziger C, Doerrier C, Krumschnabel G, Paulmichl M, Dossena S (2017) Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. PLoS One 12(6):e0179591.
Volani 2017 Metallomics	2017	Volani C, Doerrier C, Demetz E, Haschka D, Paglia G, Lavdas AA, Gnaiger E, Weiss G (2017) Dietary iron loading negatively affects liver mitochondrial function. Metallomics 9:1634-44.
Lopez 2017 PLOS ONE	2017	López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090.
Doerrier 2016 Mitochondrion	2016	Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.
Volt 2016 J Pineal Res	2016	Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.
Ortiz 2015 J Pineal Res	2015	Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
Melatonin	2015	Doerrier C (2015) Melatonin and attenuation of mitochondrial oxidative damage. Mitochondr Physiol Network 2015-03-03.
Garcia 2015 FASEB J	2015	García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75.
García-Corzo 2015 Biochim Biophys Acta	2015	García-Corzo L, Luna-Sánchez M, Doerrier C, Ortiz F, Escames G, Acuña-Castroviejo D, López LC (2015) Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta 1842:893-901.
Doerrier 2015 Thesis	2015	Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.
Ortiz 2014 J Pineal Res	2014	Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sánchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81.
Doerrier 2014 Life Sci	2014	Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.
Concepcion-Huertas 2013 J Sports Sci	2013	Concepcion-Huertas M, Chirosa LJ, De Haro T, Chirosa IJ, Romero V, Aguilar-Martinez D, Leonardo-Mendonça RC, Doerrier C, Escames G, Acuña-Castroviejo D (2013) Changes in the redox status and inflammatory response in handball players during one-year of competition and training. J Sports Sci 31:1197-207.
Escames 2013 Horm Mol Biol Clin Investig	2013	Escames G, Diaz-Casado ME, Doerrier C, Luna-Sanchez M, Lopez LC, Acuna-Castroviejo D (2013) Early gender differences in the redox status of the brain mitochondria with age: effects of melatonin therapy. Horm Mol Biol Clin Investig 16(2):91-100.
Garcia-Corzo 2013 Hum Mol Genet	2013	García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48.
Acuña-Castroviejo 2012 Age (Dordr)	2012	Acuña-Castroviejo D, Carretero M, Doerrier C, López LC, García-Corzo L, Tresguerres JA, Escames G (2012) Melatonin protects lung mitochondria from aging. Age (Dordr) 34(3):681-92.

Abstracts

	Published	Reference
Timon-Gomez 2023 EUROMIT2023 Bologna	2023	Timon-Gomez A, Cardoso L, Baglivo E, Doerrier C, Gnaiger E (2023) Mitochondrial injury in warm ischemia studied by high-resolution respirometry. EUROMIT2023 International Conference on Mitochondrial Pathology.
Cardoso 2023 BPS2023 San Diego	2023	Cardoso LHD, Timon-Gomez A, Doerrier C, Garcia-Souza LF, Gnaiger Erich (2023) Respirometric substrate-uncoupler-inhibitor titration protocols for carbohydrate and fatty acid metabolism: from heart to brain mitochondria. 67th Annual Meeting of the Biophysical Society.
Komlodi 2022 Q10 Hamburg	2022	Komlodi T, Cardoso LHD, Doerrier C, Moore AL, Rich PR, Gnaiger E (2022) The mitochondrial Q-junction and coenzyme Q pools: Continuous monitoring of pull and push control of respiration and redox state of the Q-mimetic CoQ₂. Q10 Hamburg.
Bergmeister 2022 Abstract Bioblast	2022	P11. Bergmeister Lisa, Doerrier C, Gnaiger E, Schwarzer C (2022) The role of enkephalin in hypoxic preconditioning. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
Cardoso 2022 Abstract Bioblast	2022	4.3. «10+5» Cardoso Luiza HD, Doerrier C, Donnelly C, Komlódi T, Gnaiger E (2022) Redox monitoring and respiration - a new horizon with the NextGen-O2k. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
Pallag 2022 Abstract Bioblast	2022	P06. Pallag Gergely, Nazarian S, Ravasz D, Bui D, Komlódi T, Doerrier C, Gnaiger E, Seyfried TN, Chinopoulos C (2022) Proline oxidation supports mitochondrial ATP production when Complex I is inhibited. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »MitoFit Preprint«
Doerrier 2020 PaduaMuscleDays	2020	Doerrier C, Di Marcello M, Gnaiger E (2020) Commitment to reproducibility in targeting mitochondrial respiratory control: basic and advanced applications of the O2k-FluoRespirometer. PaduaMuscleDays.
Doerrier 2020 PaduaMuscleDays Poster	2020	Doerrier C, Gama-Perez P, Chabi B, Ost M, Distefano G, Pesta D, Dahdah N, Lemieux H, Holody C, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Calabria E, Casado M, Fernandez-Ortiz M, Acuna-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wuest R, Dayanidhi S, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen PM, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Commitment to reproducibility in mitochondrial respiration studies with permeabilized muscle fibers. PaduaMuscleDays.
Doerrier 2020 MiP2020	2020
Ravasz 2019 Abstract IOC141	2019	Ravasz D, Bui D, Kitayev A, Greenwood B, Hill C, Komlodi T, Doerrier C, Ozohanics O, Moore AL, Gnaiger E, Kiebish M, Kolev K, Seyfried TN, Willis WT, Narain N, Adam-Vizi V, Chinopoulos C (2019) Endogenous quinones sustain a moderate NADH oxidation by Complex I during anoxia. Mitochondr Physiol Network 24.02.
Doerrier 2019 MiP2019	2019	Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers.
Gnaiger 2019 NatureConference	2019	Gnaiger E, Passrugger M, Gallee L, Felipe F Garcia-Souza, Zdrazilova L, Doerrier C (2019) High-resolution respirometry and innovations in the Oroboros O2k-technology.
Chabi 2019 MiP2019	2019	Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
Silva 2019 ESCI2019	2019	Silva FSG, Komlodi T, Garcia-Souza LF, Bento G, Doerrier C, Oliveira PJ, Gnaiger E (2019) Can fatty acid oxidation be specifically blocked by the CPT1 inhibitor etomoxir?
Garcia-Roves 2019 MiPschool Coimbra	2019	Generating reference values on mitochondrial respiration in permeabilized muscle fibers.
Silva 2019 MiPschool Coimbra	2019	Off-target effects of etomoxir on mitochondrial Complex I.
Doerrier 2018 ESCI2018	2018	High-resolution respirometry, two techniques combined in one to explore mitochondrial function in health and disease
Garcia-Souza 2018 Life Sciences Meeting 2018 Innsbruck AT	2018	A respirometric cell viability test for peripheral-blood mononuclear cells and platelets.
Doerrier 2018 MiP2018c	2018	Inter-laboratory study on human permeabilized myofibers: effects of fiber preparation, respiration buffer, and blebbistatin on mitochondrial respiratory capacity and oxygen limitation.
Doerrier 2018 EBEC2018	2018	Respiratory mapping of mitochondrial pathways for establishing a database of mitochondrial physiology.
Garcia-Roves 2018 MiP2018b	2018	Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report. Garcia-Roves_Presentation
Komlodi 2018b EBEC2018	2018	Endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria.
Ravasz 2018 Abstract The evolving concept of mitochondria	2018	Vast pools of endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria.
Makrecka-Kuka 2018 MiP2018	2018	Fatty acid oxidation in brain: from aging to ischemia and sepsis.
Gnaiger 2018 AussieMit	2018	Komlodi Timea, Sobotka Ondrej, Doerrier Carolina, Gnaiger Erich (2018) Mitochondrial H₂O₂ production is low under tissue normoxia but high at in-vitro air-level oxygen pressure - comparison of LEAK and OXPHOS states. AussieMit 2018 Melbourne AU.
Sobotka 2018 MiP2018	2018	Measurement of ROS production under hypoxia and unexpected methodological pitfalls of Amplex UltraRed assay.
Doerrier 2018 MiP2018b	2018	Evaluation of anaplerotic pathways to avoid artefacts in respirometric measurement of fatty acid oxidation.
Doerrier 2018 MiP2018a	2018	Inter-laboratory harmonization of protocols for mitochondrial function evaluation in permeabilized muscle fibers.
Doerrier 2017 MiPschool C2	2017	Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.
Komlodi 2017 Abstract MITOEAGLE Barcelona	2017	Succinate dehydrogenase regulation via oxaloacetate in brain mitochondria.
Garcia-Roves 2017 MiP2017	2017	Mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. MitoEAGLE WG2 pilot study. Garcia-Roves_Presentation
Doerrier 2017 Abstract MitoEAGLE Barcelona	2017	SUIT reference protocol for comparative mitochondrial physiology.
Coen 2017 MiP2017 WG2	2017	Human skeletal muscle mitochondrial function: A proposal for a state-of-the-art literature review.
Laner 2017 Abstract EUROMIT2017 Cologne	2017	K-Regio MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Doerrier 2017 MiP2017 WG2	2017	Upper limit of OXPHOS capacity in permeabilized myofibers: effect of oxygen, ADP and blebbistatin in MiR05Cr and Buffer Z.
Sobotka 2017 MiPschool Obergurgl	2017	Reference protocols for ROS production measurements.
Doerrier 2017 MiP2017 C1	2017	Effects of warm ischemia on cardiac mitochondria to detect specific targets by high-resolution respirometry (HRR)
Liebscher 2017 MiPschool Obergurgl	2017	The LAMTOR complex in regulation of fat metabolism.
Doerrier 2016 Abstract MitoFit Science Camp 2016	2016	Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
Volani 2016 Abstract MitoFit Science Camp 2016	2016	Effects of iron imbalances on mitochondrial activity in mouse liver homogenate and permabilized rat PBMCs.
Sumbalova 2016a Abstract MitoFit Science Camp 2016	2016	Optimizing strategies on the malate concentration in SUIT protocols.
Gnaiger 2016 Abstract EBEC Riva del Garda 2016	2016	MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Gnaiger 2016 Abstract SFRR Australasia 2016	2016	Facts and artefacts in measurements of H₂O₂ production under hypoxia.
Bezuidenhout 2016a Abstract MitoFit Science Camp 2016	2016	Comparison of oxygen dependence of respiration in permeabilized mouse skeletal muscle fibers in two respiration media, MiR06Cr and Buffer Z containing Ctl, Cr and Blebbistatin.
Doerrier 2016a Abstract Mito Xmas Meeting Innsbruck	2016	K-Regio MitoFit and MitoEAGLE – towards a global data bank on mitochondrial physiology.
Bezuidenhout 2016b Abstract MitoFit Science Camp 2016	2016	Analysis and comparison of mitochondrial function using cooling plate or ice during mechanical separation of mouse skeletal muscle fibers.
Doerrier 2016b Abstract Mito Xmas Meeting Innsbruck	2016	Searching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry.
Krumschnabel 2016a Abstract MitoFit Science Camp 2016	2016	O2k-Protocols: Mitochondrial preparations for HRR.
Volani 2016 Abstract Mito Xmas Meeting Innsbruck	2016	Effects of systemic iron perturbations on mitochondrial activity and on cellular metabolism in vivo.
Doerrier 2015 Abstract MiPschool Greenville 2015	2015	"Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.
Gnaiger 2015 Abstract MiP2015	2015	Mitochondrial function of cyropreserved HEK 293T cells: development of a reference sample for high-resolution respirometry.
Doerrier 2015 Abstract MiP2015	2015	Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.
Volani 2015 Abstract IOC106	2015	Volani C, Haschka D, Demetz E, Doerrier C, Gnaiger E, Weiss G (2015) Determination of mitochondrial respiration in peripheral blood mononuclear cells. Mitochondr Physiol Network 20.10.
Luna-Sánchez 2014 Abstract SECF	2014	Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment.
Volt 2014 Abstract SECF	2014	Experimental basis for the “inflammaging” theory.
Garcia 2014 Abstract SECF	2014	Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor.
Diaz-Casado 2014 Abstract SECF	2014	Melatonin restores mitochondrial regulatory gene expression and function in the zebrafish model of parkinsonism.
Volt 2014 Abstract The 2014 Ageing Summit	2014	Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis.
Doerrier 2014 Abstract SECF	2014	Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.
Ortiz 2013 Abstract SEOR	2013	Molecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin.
Luna-Sánchez 2012 Abstract MiPsummer School Cambridge	2012	CoQ deficiency: molecular and phathophysiological consequences.
Luna-Sánchez 2012 Abstract FEPS&SECF	2012	CoQ deficiency: Molecular and pathophysiological consequences.
Escames 2012 Abstract ESTRO	2012	Beneficial effects of topical melatonin against mitochondrial damage during radiotherapy-induced mucositis.
Doerrier 2012 Abstract Bioblast	2012	Doerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12.
Garcia-Corzo 2011 Abstract Euromit 8	2011	Generation of a mouse model of Coenzyme Q deficiency.
Escames 2011 Abstract FASEB Summer Research Conference	2011	Melatonin regulates the proliferation and differentation of the mice subventricular neural stem cells. Role of mitochondria.