Escames Germaine

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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

Escames Germaine

MitoPedia topics: EAGLE

COST: Member

COST WG2: WG2

COST WG4: WG4

Name	Escames Germaine, Dr., Profesora Titular de Fisiologíca
Institution	Technology Park of Health Sciences, Biomedical Research Center, Faculty of Medicine University of Granada, ES
Address	Avda. Del Conocimiento s/n, 18100
City	Armilla, Granada
State/Province
Country	Spain
Email	[email protected]
Weblink
O2k-Network Lab	ES Granada Acuna-Castroviejo D

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Publications

	Published	Reference
BEC 2020.1 doi10.26124bec2020-0001.v1	2020	Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Lopez 2017 PLOS ONE	2017	López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090.
Doerrier 2016 Mitochondrion	2016	Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.
Volt 2016 J Pineal Res	2016	Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.
Garcia 2015 FASEB J	2015	García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75.
García-Corzo 2015 Biochim Biophys Acta	2015	García-Corzo L, Luna-Sánchez M, Doerrier C, Ortiz F, Escames G, Acuña-Castroviejo D, López LC (2015) Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta 1842:893-901.
Ortiz 2015 J Pineal Res	2015	Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
Acuña-Castroviejo 2014 Cell Mol Life Sci	2014	Acuña-Castroviejo D, Escames G, Venegas C, Díaz-Casado ME, Lima-Cabello E, López LC, Rosales-Corral S, Tan DX, Reiter RJ (2014) Extrapineal melatonin: sources, regulation, and potential functions. Cell Mol Life Sci 71:2997-25.
Doerrier 2014 Life Sci	2014	Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.
Ortiz 2014 J Pineal Res	2014	Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sánchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81.
Garcia-Corzo 2013 Hum Mol Genet	2013	García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48.
Escames 2013 Horm Mol Biol Clin Investig	2013	Escames G, Diaz-Casado ME, Doerrier C, Luna-Sanchez M, Lopez LC, Acuna-Castroviejo D (2013) Early gender differences in the redox status of the brain mitochondria with age: effects of melatonin therapy. Horm Mol Biol Clin Investig 16(2):91-100.
Concepcion-Huertas 2013 J Sports Sci	2013	Concepcion-Huertas M, Chirosa LJ, De Haro T, Chirosa IJ, Romero V, Aguilar-Martinez D, Leonardo-Mendonça RC, Doerrier C, Escames G, Acuña-Castroviejo D (2013) Changes in the redox status and inflammatory response in handball players during one-year of competition and training. J Sports Sci 31:1197-207.
Acuña-Castroviejo 2012 Age (Dordr)	2012	Acuña-Castroviejo D, Carretero M, Doerrier C, López LC, García-Corzo L, Tresguerres JA, Escames G (2012) Melatonin protects lung mitochondria from aging. Age (Dordr) 34(3):681-92.
Acuña-Castroviejo 2011 Curr Top Med Chem	2011	Acuña-Castroviejo D; López LC; Escames G; López A; García JA; Reiter RJ (2011) Melatonin-mitochondria interplay in health and disease. Curr Top Med Chem 11:221-240.
Lopez 2009 J Pineal Res	2009	López A, García JA, Escames G, Venegas C, Ortiz F, López LC, Acuña-Castroviejo D (2009) Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production. J Pineal Res 46:188-98.

Abstracts

	Published	Reference
Acuna-Castroviejo 2018 MiP2018	2018	Mitochondria, melatonin, and neuroinflammation in Parkinson's disease. Acuna-Castroviejo_Presentation
Escames 2018 MiP2018	2018	Suppression of AKT/mTOR pathway and activation of mitophagy by melatonin via mitocondrial regulation in head and neck cancer. Escames_Presentation
Doerrier 2014 Abstract SECF	2014	Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.
Luna-Sánchez 2014 Abstract SECF	2014	Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment.
Volt 2014 Abstract SECF	2014	Experimental basis for the “inflammaging” theory.
Garcia 2014 Abstract SECF	2014	Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor.
Diaz-Casado 2014 Abstract SECF	2014	Melatonin restores mitochondrial regulatory gene expression and function in the zebrafish model of parkinsonism.
Volt 2014 Abstract The 2014 Ageing Summit	2014	Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis.
Ortiz 2013 Abstract SEOR	2013	Molecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin.
Doerrier 2012 Abstract Bioblast	2012	Doerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12.
Luna-Sánchez 2012 Abstract MiPsummer School Cambridge	2012	CoQ deficiency: molecular and phathophysiological consequences.
Luna-Sánchez 2012 Abstract FEPS&SECF	2012	CoQ deficiency: Molecular and pathophysiological consequences.
Escames 2012 Abstract ESTRO	2012	Beneficial effects of topical melatonin against mitochondrial damage during radiotherapy-induced mucositis.
Garcia-Corzo 2011 Abstract Euromit 8	2011	Generation of a mouse model of Coenzyme Q deficiency.
Escames 2011 Abstract FASEB Summer Research Conference	2011	Melatonin regulates the proliferation and differentation of the mice subventricular neural stem cells. Role of mitochondria.

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