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Bioblast Agenda - 2024 week 38
2024 Week 38
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World Mitochondrial Disease Week – Sep 16-22
World Mitochondrial Disease Week raises awareness of mitochondrial disease through educational, fundraising and advocacy activities.
»See what is happening near you«
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What are coupling-control states?
They are defined as LEAK respiration, OXPHOS and ET states, with corresponding respiration rates (L, P, and E respectively), in the various mitochondrial preparations.
- »Coupling-control state«
- communicated by »Willis Jaime R« and »Baglivo Eleonora«
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There is no current cure for mitochondrial diseases
Most treatments and medication focus on alleviating the symptoms associated with the disease and slowing the course of the disease.
- »Mitochondrial disease«
- communicated by »Timon-Gomez Alba« and »Cardoso Luiza«
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- EMC2024 Ljubljana SI 2024 Sep 22-26
Next Week
2024 Week 39
- EMC2024 Ljubljana SI 2024 Sep 22-26
 
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The oxygen concentration is unusually high or low when starting a new measurement?
When starting a new measurement, the oxygen concentration is calculated by DatLab based on the default values or the most recently applied air calibration. If the temperature, barometric pressure, or solubility factor differ between the actual measurement and the default settings or the most recently performed and applied air calibration, the calculated oxygen concentration can be very different from the actual oxygen concentration.
- »Oxygen signal«
- communicated by »Schmitt Sabine« and »Willis Jaime R«
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"The coupling sites are the respiratory Complexes CI, CIII, and CIV which pump protons towards the intermembrane space ... Pathways with a lower number of coupling sites are less likely to saturate the phosphorylation system capacity at identical rates of O2 consumption."
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 Oroboros O2k-Workshop IOC166 Ljubljana SI Sep 26
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"Understanding the degree by which a specific cancer type utilizes mitochondria for processes such as macromolecule synthesis and energy transfer is required to ultimately determine targetability and therapeutic potential."
- Zunica ERM, Axelrod CL, Gilmore LA, Gnaiger E, Kirwan JP (2024) The bioenergetic landscape of cancer. »Bioblast link«
- from the O2k-Network »US LA Baton Rouge Noland RC« and »AT Innsbruck Oroboros«
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In focus
Stay alert
Oroboros of the month
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- In the artwork "First Fruits of the Earth Offered to Saturn" at the Palazzo Vecchio, Saturn (Cronus in Greek mythology) is holding the Ouroboros in the hand, symbolizing the eternal cycle of renewal and the interconnectedness of beginning and end.
- » Oroboros pictures of the month
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