Template:SUIT PGM low ADP: Difference between revisions
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The addition of PGM may trigger a transient peak increase in mitochondrial respiration due to the presence of low ADP concentrations, and reduction of the NAD pool. Once ADP is phosphorylated to ATP the respiration decreases and a further reduction of NAD can be observed. | |||
*In the presence of ATPase in the sample, ATP is recycled to ADP, making it not possible to measure LEAK state. | |||
Revision as of 15:10, 20 December 2023
The addition of PGM may trigger a transient peak increase in mitochondrial respiration due to the presence of low ADP concentrations, and reduction of the NAD pool. Once ADP is phosphorylated to ATP the respiration decreases and a further reduction of NAD can be observed.
- In the presence of ATPase in the sample, ATP is recycled to ADP, making it not possible to measure LEAK state.
