|
Tag: Redirect target changed |
| (35 intermediate revisions by 3 users not shown) |
| Line 1: |
Line 1: |
| {{MitoPedia
| | #REDIRECT [[Electron-transfer-pathway state]] |
| |description=[[File:SUITp-Catg NFSGpTm.jpg|right|300px]]
| |
| '''Substrate types''' in SUIT protocols are types of reduced substrates feeding electrons into the [[electron transfer system]] (ETS) at different levels of mitochondrial pathways. Substrates of type 1 may be artificial electron donors essentially bypassing the ETS and feeding electrons directly into the terminal electron acceptor, cytochrome c oxidase (CIV) or alternative oxidases (single enzymatic step). Substrates of type 2 feed electrons into Complex III (CIII) with further electron transfer downstream of the [[Q-junction]]. Substrates of type 3 feed electrons into respiratory complexes directly upstream of the Q-junction, whereas substrates of type 4 feed electrons into dehydrogenases and enzyme systems upstream of the type 3 pathway level.
| |
| }}
| |
| {{MitoPedia concepts
| |
| |mitopedia concept=MitoFit Quality Control System
| |
| }}
| |
| {{MitoPedia methods}}
| |
| {{MitoPedia SUIT
| |
| |mitopedia SUIT=SUIT protocol
| |
| }}
| |
| {{MitoPedia topics
| |
| |mitopedia topic=Substrate and metabolite
| |
| }}
| |
| * On the pathway level of converging NADH- and FADH<sub>2</sub>-linked dehydrogenases, including the TCA cycle and beta-oxidation:
| |
| | |
| :'''N:''' [[NADH]]-linked substrates (CI-linked)
| |
| | |
| :'''F:''' [[FADH2 |FADH<sub>2</sub>]]-linked substrates (FAO)
| |
| | |
| * On the pathway level of electron transfer complexes converging at the Q-junction:
| |
| | |
| :'''S:''' [[Succinate]] (CII-linked)
| |
| | |
| :'''Gp:''' [[Glycerophosphate]] (CGpDH-linked)
| |
| | |
| * On the single step level of cytochrome ''c'' oxidase (CIV), the terminal step in the aerobic electron transfer system:
| |
| | |
| :'''Tm:''' Artificial electron transfer susbstrate [[TMPD]] (Tm) maintained in a reduced state by [[ascorbate]] (As) and reducing cytochrome ''c'' as the substrate of [[CIV]].
| |
