Description
The Q-junction is a junction for convergent electron flow in the electron transfer system (ETS) from type N substrates through Complex I (CI), from succinate (S) through Complex II (CII), from type F substrates and FA oxidation through electron-transferring flavoprotein complex (CETF), from glycoreophosphate (Gp) thorughglycerophosphate dehydrogenase complex (CGpDH), from choline through choline dehydrogenase, from dihydro-orotate through dihydro-orotate dehydrogenase, and other enzyme complexes into the Q-cycle (ubiquinol/ubiquinone), and further downstream to Complex III (CIII) and CIV. The concept of the Q-junction, with the N-junction and F-junction upstream, provides the rationale for defining categories of SUIT protocols.
Abbreviation: Q
Reference: Gnaiger 2009 Int J Biochem Cell Biol, Gnaiger 2014 MitoPathways
MitoPedia methods: Respirometry
MitoPedia O2k and high-resolution respirometry: "SUIT protocol" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property.
SUIT protocol"SUIT protocol" is not in the list (O2k hardware, DatLab, Oroboros QM, O2k-Open Support, O2k-Respirometry, O2k-FluoRespirometry) of allowed values for the "MitoPedia O2k and high-resolution respirometry" property.
MitoPedia topics:
Enzyme
Contributed by Gnaiger E 2010-08-15, edited 2016-02-12.
- Convergent NS-linked electron flow at the Q-junction, exerting an additive effect on flux, versus electron gaiting for separation of single N- and S-input pathways (upper panel: Gnaiger 2009; lower panel: Hatefi 1962 J Biol Chem-XLII). Modified Fig. 1.5 in Gnaiger 2014 MitoPathways.