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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
WG1 MitoEAGLE protocols, terminology, documentation
WG1 Action
- Standard operating procedures and user requirement document: Protocols, terminology, documentation
- Many analyses lack statistical power within a single study. Statistical combination of different studies is often difficult due to lack of methodological standardization and harmonization.
WG Leader
- Kathrin Renner-Sattler, Mag. Dr. - [email protected]
WG Co-Leader
- Marko Vendelin, Dr. - [email protected]
Participants and discussion
Accomplished
Task groups
- TG leaders: suggestions discussed at the MitoFit Science Camp 2016 Kuehtai AT, and updated according to the MITOEAGLE MC Meeting 2016 Brussels BE.
- TG participants: summary of the feedback received.
TG1.1 Coupling states and coupling control ratios: consensus statements
- TG leaders: Renner-Sattler Kathrin DE / Gnaiger Erich AT / Hoppel Charles L US
- TG participants:
TG1.2 SUIT protocols: nomenclature consistent with concept of database
- TG leader: Doerrier Velasco Carolina A AT, Gnaiger Erich AT
- TG participants: Attimonelli Marcella IT, Krako Nina RS, Vendelin Marko EE
TG1.3 Experimental details in SUIT
- TG leaders: Chicco Adam J US/ Hickey Anthony J NZ/ Doerrier Velasco Carolina A AT
- TG participants: Casado Pinna Marta ES, Krako Nina RS
TG1.4 Instrumental platforms: comparisons
- TG leaders: Molina Anthony JA US
- TG participants: Canto Carles CH (suggested), Genova Maria Luisa IT, Tronstad Karl Johan NO (suggested), Vendelin Marko EE, Zorzano Antonio ES (suggested)
TG1.5 Knowledge management system
- TG leaders: Drinnan Michael UK / Plattner Christina AT
- TG participants: Vendelin Marko EE, Garcia-Roves Pablo ES
- Towards and beyond a mitochondrial physiology database: filter and amplify more signals from this data, making them more meaningful and valuable for research and medicine.
TG1.6 Proficiency test
- TG leaders: Gnaiger Erich AT/ Doerrier Velasco Carolina A AT
- TG participants: Genova Maria Luisa IT, Plattner Christina AT
TG1.7 Documentation
- TG leaders: Arnould Thierry BE/ Votion Dominique-Marie BE
- TG participants:
TG1.8 Translation to community in general
- TG leader: Makrecka-Kuka Marina LV (Dissemination Coordinator), Rattan Suresh DK
- TG participants: Krako Nina RS, Irving Brian A US
TG1.9 Dissemination Scientific community
- TG leaders: Makrecka-Kuka Marina LV / Gnaiger Erich AT
- TG participants: Ali Sameh S EG, Cervinkova Zuzana CZ, Chicco Adam J US, Coen Paul M US, Eide Lars NO, Garcia-Roves Pablo M ES, Gasparre Giuseppe IT, Genova Maria Luisa IT, Haendeler Judith DE, Iyer Shilpa US, Krako Nina RS, Laner Verena AT, Mayan Maria D ES, Mishmar Dan IL, Nehlin Jan DK, Palmeira Carlos PT, Paterlini Serena IT, Porcelli Anna Maria IT, Rao Raj US, Schaefer Patrick DE, Tronstad Karl Johan NO, Trougakos Ioannis GR, Volani Chiara AT, Votion Dominique-Marie BE
TG1.10 Training, Short Term Scientific Missions
- TG leader: Labieniec-Watala Magdalena PL, Klaus Susanne DE
- TG participants: Ali Sameh S EG, Cervinkova Zuzana CZ, Chicco Adam J US, Coen Paul M US, Eide Lars NO, Garcia-Roves Pablo M ES, Gasparre Giuseppe IT, Genova Maria Luisa IT, Haendeler Judith DE, Iyer Shilpa US, Krako Nina RS, Mayan Maria D ES, Mishmar Dan IL, Nehlin Jan DK, Palmeira Carlos PT, Paterlini Serena IT, Porcelli Anna Maria IT, Rao Raj US, Schaefer Patrick DE, Tronstad Karl Johan NO, Trougakos Ioannis GR, Volani Chiara AT, Votion Dominique-Marie BE
Projects in progress
- Interlaboratory proficiency ring test
- Testing of software components
- Concepts and terminology on mitochondrial physiology
- Procedures and experimental protocols for the evaluation of mitochondrial capacities, library of protocols
- Data management system (DMS)
- Β» MitoFit-KMP
- Data management system (DMS)
- Database
Next steps
- Β» MITOEAGLE 2017 Barcelona ES
- Β» MiPschool Obergurgl 2017
- Best practices for implementation of analytical and process standards.
References
- General requirements for the competence of testing and calibration laboratories Β» ISO/IEC 17025:2005