Cookies help us deliver our services. By using our services, you agree to our use of cookies. More information

Difference between revisions of "Weissig 2015 Methods Mol Biol I"

From Bioblast
ย 
(8 intermediate revisions by one other user not shown)
Line 1: Line 1:
{{Publication
{{Publication
|title=Weissig V, Edeas M, eds (2015) Mitochondrial medicine: Volume I, Probing mitochondrial function. Methods Mol Biol 1264:1-480.
|title=Weissig V, Edeas M, eds (2015) Mitochondrial medicine: Volume I, Probing mitochondrial function. Methods Mol Biol 1264:1-480.
|info=[http://link.springer.com/book/10.1007/978-1-4939-2257-4#page=334 Springer]
|info=[http://link.springer.com/book/10.1007/978-1-4939-2257-4#page=334 Springer Protocols]
|authors=Weissig V, Edeas M
|authors=Weissig V, Edeas M
|year=2015
|year=2015
|journal=Methods Mol Biol Mitochondrial medicine: Volume I
|journal=Methods Mol Biol
|abstract=Preface: Mitochondrial Medicine is an interdisciplinary and rapidly growing new area of biomedical
|abstract=This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction. It dedicates itself to showcasing the tremendous efforts and the progress that has been made over the last decades in developing techniques and protocols for probing, imaging, and manipulating mitochondrial functions. Mitochondrial Medicine: Methods and Protocols, Volume I: Probing Mitochondrial Function focuses on methods being used for the assessment of mitochondrial function under physiological conditions as well as in healthy isolated mitochondria. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
research comprising genetic, biochemical, pathological, and clinical studies aimed at the
Comprehensive and practical, Mitochondrial Medicine: Methods and Protocols provides an essential source of know-how and inspiration to all researchers who are fascinated by this tiny organelle that seems so clearly to control the life and death of a single cell and whole organisms alike.
diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction. The term โ€œMitochondrial Medicineโ€ was probably used for the first time by Rolf Luft [1] who is widely accepted as the father of Mitochondrial Medicine. Over 50 years ago, it was he who described for the very first time a patient with clinical symptoms
|keywords=Apoptosis, Deep sequencing, Human mitochondrial DNA, Mitochondria isolation, Mitochondria-related diseases, Next generation sequencing, mtDNA
caused by malfunctioning mitochondria [2]. The beginning of mitochondria-related research dates back to the end of the nineteenth century. During the 1890s, early cytological studies revealed the existence of
bacteria- resembling subcellular particles in the cytosol of mammalian cells. Richard Altman termed them bioblasts, and he hypothesized that these particles were the basic unit of cellular activity. The name mitochondrion, which means thread-like particles, was coined in 1898 by Carl Benda. During the 1940s, progress was made in the development of cell fractionation techniques which ultimately allowed the isolation of intact mitochondria from cell homogenates, thereby making them more accessible to biochemical studies.
Subsequently, by the end of the 1940s, activities of a variety of enzymes needed for fatty
acid oxidation, the Krebs cycle, and other metabolic pathways were found to be associated
with mitochondrial fractions.
ย 
[http://download.springer.com/static/pdf/312/bfm%253A978-1-4939-2257-4%252F1.pdf?auth66=1423037376_fa338d2864c8adefa5ec7852512054b1&ext=.pdf ''Read more'']
}}
}}
{{Labeling
{{Labeling
Line 21: Line 14:
}}
}}
* 'Robert Altmann', as written in the original text, should be corrected to '''Richard Altmann''': [[Bioblasts |''more details'']]
* 'Robert Altmann', as written in the original text, should be corrected to '''Richard Altmann''': [[Bioblasts |''more details'']]
[[Weissig 2015 Methods Mol Biol II | check out Volume II - Manipulating mitochondrial function]]


== Contents ==
== Contents ==


[http://link.springer.com/book/10.1007/978-1-4939-2257-4#page=334 Table of contents]
[http://www.springer.com/biomed/molecular/book/978-1-4939-2256-7 Table of contents]


[[Krumschnabel 2015 Methods Mol Biol]]
[[Krumschnabel 2015 Methods Mol Biol]]
[[Bros 2015 Methods Mol Biol]]

Latest revision as of 11:32, 7 March 2016

Publications in the MiPMap
Weissig V, Edeas M, eds (2015) Mitochondrial medicine: Volume I, Probing mitochondrial function. Methods Mol Biol 1264:1-480.

ยป Springer Protocols

Weissig V, Edeas M (2015) Methods Mol Biol

Abstract: This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction. It dedicates itself to showcasing the tremendous efforts and the progress that has been made over the last decades in developing techniques and protocols for probing, imaging, and manipulating mitochondrial functions. Mitochondrial Medicine: Methods and Protocols, Volume I: Probing Mitochondrial Function focuses on methods being used for the assessment of mitochondrial function under physiological conditions as well as in healthy isolated mitochondria. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Mitochondrial Medicine: Methods and Protocols provides an essential source of know-how and inspiration to all researchers who are fascinated by this tiny organelle that seems so clearly to control the life and death of a single cell and whole organisms alike. โ€ข Keywords: Apoptosis, Deep sequencing, Human mitochondrial DNA, Mitochondria isolation, Mitochondria-related diseases, Next generation sequencing, mtDNA


Labels: MiParea: Respiration, mt-Medicine, Patients 





HRR: Oxygraph-2k 


  • 'Robert Altmann', as written in the original text, should be corrected to Richard Altmann: more details

check out Volume II - Manipulating mitochondrial function

Contents

Table of contents

Krumschnabel 2015 Methods Mol Biol