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About Oroboros Instruments


The Team

Founded in 1994 and based in Innsbruck, Austria, Oroboros Instruments boasts more than 25 years of experience, making us the expert in mitochondrial and cell research. Labs, hospitals, research centers, pharmaceutical and biotech companies in 49 countries are benefiting from our gold standard Oroboros O2k technology for high-resolution respirometry (HRR) and from the robustness, reliability and high quality of our products. The O2k-Network includes and connects over 600 reference laboratories worldwide. Further benefitting our customers, we organize international O2k-Workshops on a regular basis, allowing for hands-on practical training provided by our experts.


Our international team has the skills, knowledge, and creativity to bring innovation and excellence to the relevant markets. By actively participating in research (see: publications) along with hosting international researchers (visiting scientists) in the fully equipped Oroboros MitoFit Laboratory, our science specialists fully understand what is required to conduct excellent research. They develop tested and trusted O2k instruments and protocols that enable researchers and clinicians to study mitochondrial function in cancer, diabetes, aging, neurodegeneration, exercise physiology and mitochondrial medicine.


About Our Products

O2k-FluoRespirometer
Template NextGen-O2k.jpg

Oroboros O2k represents the unique concept of the modular O2k-system for high-resolution respirometry (HRR). The O2k is applied worldwide in areas ranging from fundamental bioenergetics to the analysis of mitochondrial and metabolic diseases, advancing the rapidly growing field of preventive mitochondrial medicine. Mitochondrial fitness requires monitoring in a variety of age-related health risks, such as cancer, cardiovascular, degenerative, and neurodegenerative diseases.

Our flagship package is the O2k-FluoRespirometer for mitochondria and cell research. Small amounts of biological samples can be used for bioenergetic and OXPHOS analysis, ranging from isolated mitochondria, permeabilized tissues and permeabilized cells to intact cells and tissues slices.The modular O2k-concept is supported by specially developed O2k-Software, DatLab 7, with high flexibility for extension by add-on O2k-Modules or economical first steps with the Startup O2k-Respirometer. The high-resolution O2k technology emphasizes quality and scientific output of research in mitochondrial physiology and pathology.


  • The O2k-FluoRespirometer can be used for simultaneous monitoring of oxygen consumption and either ROS production (AmR), mitochondrial (mt-) membrane potential (TMRM, Safranin and Rhodamine), Ca2+ (CaG) or ATP production (MgG).
  • Add-on MultiSensor modules enable measurement of mt-membrane potential with ion sensitive electrodes (for TPP+ or TPMP+), Ca2+ or pH.
  • O2k software DatLab for data acquisition and analysis provides protocols for quality control and substrate-uncoupler-inhibitor titration (SUIT) protocols, guiding the user step-by-step through the desired experiment.
  • Further extended by novel Q-redox and PhotoBiology modules, the NextGen-O2k is being developed as the all-in-one device for real-time monitoring of mitochondrial/chloroplast function. Its innovations, built upon the Oroboros O2k technology, ensure reproducible and accurate results.


Mission & Vision

Our Mission In progress -

Oroboros Instruments distributes the gold standard O2k-technology high resolution respirometry for mitochondria and cell research - the leading technology for diagnostic evaluation of mitochondrial respiratory function. Our pursuit for continuous innovation has enabled us to launch our next big project, the NextGen-O2k instrument, which on the one hand extends the analytical and diagnostic power of high-resolution respirometry by integration of NADH- and Q-redox and on the other hand expands our business to algal biotechnology and ecology with the photobiology module of the NextGen-O2k, widening our focus from medicine to environment and climate.

Our main mission is to address the acute reproducibility crisis of scientific investigation through precise quality control. In the spirit of Gentle Science and global networking, we recognize the responsibility of the scientific community. To resolve the inflation crisis and ultimately the value-impact crisis of present academic publications, will enable data sharing across projects and institutions in an Open Access database on mitochondrial physiology and pathology. Giving expert user support to our world-wide scientific network and collaborations, we aim to train our future inventors and start-ups. With our focus on corporate social responsibility, we will support key developments in mitochondrial medicine and contribute valuable benefits for our health system through putting pressure on the importance of mitochondrial fitness.


Our Vision In progress-

We believe in defining the future of mitochondria and cell research by not only focusing on continuous innovation and user-friendly approaches of our instruments but also by aiming for a consistent nomenclature in mitochondrial physiology. Our vision to be the leading scientific driving force in mitochondrial physiology is guided by our aspiration to equip each biomedical lab world-wide with our instruments for research and diagnostic screening which makes it possible for them to study mitochondrial function in cancer, diabetes, aging, neurodegeneration, exercise physiology and mitochondrial medicine. We strive for optimal harmonization of protocols across research groups and thus support the development of databases of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery.

Corporate Social Responsibility

At Oroboros Instruments we are committed to not only our work, but also the way we do it. Our culture includes respect and support for our community as well as concern for the environment. Over 25 years of experience in innovation, development and optimization have led to the best quality scientific instruments with minimum running costs. To reduce our environmental impact, we design and produce our devices to be energy efficient and long-lasting. The durability and robustness of our instruments mean less waste. Further waste-reduction practices, such as providing an electronic version of our manuals, are part of our approach to conservation. Our team is dedicated to this ethic and we encourage all our employees to contribute. Like our instruments we strive to continually develop our employees by challenging them and fostering the exchange of knowledge. Our diverse, multicultural and open team shares this philosophy and leads us to our growth. Every employeeโ€™s opinion matters, and their breadth of experience helps us continually improve our company and our products.



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