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Difference between revisions of "Template:Current week ecosystem agenda"

From Bioblast
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  2021 Week 49
  2021 Week 50


*'''Dec-06 Mo'''
*'''Dec-13 Mo'''  
 
:{|
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*'''Dec-07 Tu'''
:{|
| width="110" align="center" | [[File:Gnaiger 2020 BEC MitoPathways.jpg|70px|link=https://www.bioenergetics-communications.org/index.php/bec/article/view/gnaiger_2020_mitopathways|Gnaiger 2020 BEC MitoPathways]]
|'''What is ROUTINE respiration?'''<br>
ROUTINE respiration is the respiratory activity of living (non-permeabilized) cells in the physiological coupling state, which is controlled by cellular energy demand, energy turnover and the degree of coupling to phosphorylation. <br>
- »[https://www.bioenergetics-communications.org/index.php/bec/article/view/gnaiger_2020_mitopathways Gnaiger 2020 BEC MitoPathways - Chapter 2.4]« <br>
- communicated by »[[Komlodi Timea]]« and »[[Schmitt Sabine]]«
|}
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*'''Dec-08 We'''
:{|
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia]]
| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia]]
|'''The central role of the Q-junction in mitochondria'''<br>
|'''Why use a short-chain coenzyme Q mimetic for measurement of the Q-redox state using the Q-Module? '''<br>
The Q-junction is a point of convergence in the electron transfer system. Electrons flow from different dehydrogenases and respiratory Complexes into the Q-junction and then downstream to Complex III. <br>
The naturally occurring long-isoprenoid chain coenzyme Q (e.g. CoQ<sub>10</sub> or CoQ<sub>9</sub>) is trapped within membrane boundaries. Therefore, a short-chain, membrane-permeable CoQ mimetic, CoQ<sub>2</sub> is used as a probe which reacts with the mitochondrial respiratory Complexes at their quinone-binding sites and with the working electrode of the Q-sensor.<br>
- »[[Q-junction]]« <br>
- »[https://wiki.oroboros.at/index.php/Coenzyme_Q2 Coenzmye Q<sub>2</sub>]« and »[[Q-Module]]« <br>
- communicated by »[[Komlodi Timea]]« and »[[Schmitt Sabine]]« <br>
- communicated by »[[Komlodi Timea]]« and »[[Schmitt Sabine]]« <br>
|}
|}
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*'''Dec-09 Th'''
*'''Dec-14 Tu'''
 
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*'''Dec-15 We'''  
:{|
:{|
| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
|'''How do you measure ROUTINE respiration?'''<br>
|''' Exercise increased mitochondrial respiration in adipose tissue in prediabetics, whereas in skeletal muscle only mitochondrial content was increased''' <br>
ROUTINE respiration (''R'') of living cells is measured before permeabilization of the cell membrane either in cell culture medium or any other respiration media (e.g. MiR05) in the presence or absence of exogenous substrates. Allow ''R'' to stabilize for 15-20 min. <br>
* Szczerbinski L, Taylor MA, Puchta U, Konopka P, Paszko A, Citko A, Szczerbinski K, Goscik J, Gorska M, Larsen S, Kretowski A (2021) The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes. Cells 10:3013. [[Szczerbinski 2021 Cells|»Bioblast link«]]
- »[[ROUTINE respiration]]« and »[[Doerrier 2018 Methods Mol Biol]]« <br>
:from the O2k-Network »[[DK Copenhagen Larsen S]]«  
- communicated by »[[Komlodi Timea]]« and »[[Schmitt Sabine]]«
|}
|}
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*'''Dec-16 Th'''
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*'''Dec-10 Fr'''
*'''Dec-17 Fr'''

Revision as of 09:05, 13 December 2021

2021 Week 50
  • Dec-13 Mo
MitoPedia
Why use a short-chain coenzyme Q mimetic for measurement of the Q-redox state using the Q-Module?

The naturally occurring long-isoprenoid chain coenzyme Q (e.g. CoQ10 or CoQ9) is trapped within membrane boundaries. Therefore, a short-chain, membrane-permeable CoQ mimetic, CoQ2 is used as a probe which reacts with the mitochondrial respiratory Complexes at their quinone-binding sites and with the working electrode of the Q-sensor.
- »Coenzmye Q2« and »Q-Module« 
- communicated by »Komlodi Timea« and »Schmitt Sabine« 


  • Dec-14 Tu

  • Dec-15 We
O2k-Publications in the MiPMap Exercise increased mitochondrial respiration in adipose tissue in prediabetics, whereas in skeletal muscle only mitochondrial content was increased
  • Szczerbinski L, Taylor MA, Puchta U, Konopka P, Paszko A, Citko A, Szczerbinski K, Goscik J, Gorska M, Larsen S, Kretowski A (2021) The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes. Cells 10:3013. »Bioblast link«
from the O2k-Network »DK Copenhagen Larsen S«

  • Dec-16 Th

  • Dec-17 Fr