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Difference between revisions of "Talk:Body fat excess"

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(Created page with " ''Work in progress'' === Body fat in the healthy reference population === :::: Lean body mass, ''M''<sub>L</sub> [kg], is the fat-free body mass, and is thus defined as...")
 
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:::: [[Lean body mass]], ''M''<sub>L</sub> [kg], is the fat-free body mass, and is thus defined as ''M''<sub>L</sub> <big>≝</big> ''M''-''m''<sub>F</sub>,
:::: [[Lean body mass]], ''M''<sub>L</sub> [kg], is the fat-free body mass, and is thus defined as ''M''<sub>L</sub> <big>≝</big> ''M''-''m''<sub>F</sub>,


  <big>''M'' <big>≝</big> ''M''<sub>L</sub> + ''m''<sub>F</sub>                         (Eq. 2)</big>
  <big>'''Eq. 2''':  ''M'' <big>≝</big> ''M''<sub>L</sub> + ''m''<sub>F</sub></big>


:::: In turn, ''M'' is the sum of the reference mass at a given height and excess body mass, ''M''<sub>E</sub> <big>≝</big> ''M''-''M''°,
:::: In turn, ''M'' is the sum of the reference mass at a given height and excess body mass, ''M''<sub>E</sub> <big>≝</big> ''M''-''M''°,


  <big>''M'' <big>≝</big> ''M''° + ''M''<sub>E</sub>                                 (Eq. 3)</big>
  <big>'''Eq. 3''':  ''M'' <big>≝</big> ''M''° + ''M''<sub>E</sub></big>


:::: Excess body mass, ''M''<sub>E</sub>, is due to accumulation of an excess fat mass, ''m''<sub>FE</sub>, accompanied by a gain of excess lean mass, ''m''<sub>LE</sub>, which includes increased bone mineral density, added bone mass and muscle mass due to the mechanical 'weight-lifting effect' ([[Iwaniec 2016 J Endocrinol]]). Thus Eq. 2 and 3 combined yield the definition for excess body mass,
:::: Excess body mass, ''M''<sub>E</sub>, is due to accumulation of an excess fat mass, ''m''<sub>FE</sub>, accompanied by a gain of excess lean mass, ''m''<sub>LE</sub>, which includes increased bone mineral density, added bone mass and muscle mass due to the mechanical 'weight-lifting effect' ([[Iwaniec 2016 J Endocrinol]]). Thus Eq. 2 and 3 combined yield the definition for excess body mass,


  <big>''M''<sub>E</sub> <big>≝</big> ''m''<sub>FE</sub> + ''m''<sub>LE</sub>                         (Eq. 4)</big>
  <big>'''Eq. 4''':  ''M''<sub>E</sub> <big>≝</big> ''m''<sub>FE</sub> + ''m''<sub>LE</sub></big>


:::: Inserting Eq. 4 into Eq. 3,
:::: Inserting Eq. 4 into Eq. 3,


  <big>''M'' = ''M''° + ''m''<sub>FE</sub> + ''m''<sub>LE</sub>                           (Eq. 5)</big>
  <big>'''Eq. 5''':  ''M'' = ''M''° + ''m''<sub>FE</sub> + ''m''<sub>LE</sub></big>


:::: The fat mass, ''m''<sub>F</sub>, is defined as the sum of the reference fat mass and excess fat mass, ''m''<sub>F</sub> <big>≝</big> ''m''°<sub>F</sub>+''m''<sub>FE, hence
:::: The fat mass, ''m''<sub>F</sub>, is defined as the sum of the reference fat mass and excess fat mass, ''m''<sub>F</sub> <big>≝</big> ''m''°<sub>F</sub>+''m''<sub>FE, hence


  <big>''m''<sub>FE</sub> <big>≝</big> ''m''<sub>F</sub> - ''m''°<sub>F</sub>                           (Eq. 6)</big>
  <big>'''Eq. 6''':  ''m''<sub>FE</sub> <big>≝</big> ''m''<sub>F</sub> - ''m''°<sub>F</sub></big>


:::: Inserting Eq. 6 into Eq. 5 yields body mass as the sum of the reference mass minus reference fat mass (which is the reference lean mass, ''M''°<sub>L</sub> = ''M''-''m''°<sub>F</sub>), plus the total body fat mass and the excess lean mass,
:::: Inserting Eq. 6 into Eq. 5 yields body mass as the sum of the reference mass minus reference fat mass (which is the reference lean mass, ''M''°<sub>L</sub> = ''M''-''m''°<sub>F</sub>), plus the total body fat mass and the excess lean mass,


  <big>''M'' = ''M''° - ''m''°<sub>F</sub> + ''m''<sub>F</sub> + ''m''<sub>LE</sub>                 (Eq. 7)</big>
  <big>'''Eq. 7''':  ''M'' = ''M''° - ''m''°<sub>F</sub> + ''m''<sub>F</sub> + ''m''<sub>LE</sub></big>


:::: Normalization for ''M''° and considering that the [[body mass excess]] is BME=''M''/''M''°-1,
:::: Normalization for ''M''° and considering that the [[body mass excess]] is BME=''M''/''M''°-1,


  <big>BME = ''m''<sub>F</sub>/''M''° - ''m''°<sub>F</sub>/''M''° + ''m''<sub>LE</sub>/''M''°             (Eq. 8)</big>
  <big>'''Eq. 8''':  BME = ''m''<sub>F</sub>/''M''° - ''m''°<sub>F</sub>/''M''° + ''m''<sub>LE</sub>/''M''°</big>


:::: The excess lean mass normalized for ''M''° is a function of BME,
:::: The excess lean mass normalized for ''M''° is a function of BME,


  <big>''m''<sub>LE</sub>/''M''° = ''f''(BME)                                            (Eq. 9)</big>
  <big>'''Eq. 9''':  ''m''<sub>LE</sub>/''M''° = ''f''(BME)</big>


:::: Inserting Eq. 8 and 9 into Eq. 7.2 yields
:::: Inserting Eq. 8 and 9 into Eq. 7.2 yields


  <big>BME = ''m''<sub>F</sub>/''M''° - ''m''°<sub>F</sub>/''M''° + ''f''(BME)                  (Eq. 10)</big>  
  <big>'''Eq. 10''':  BME = ''m''<sub>F</sub>/''M''° - ''m''°<sub>F</sub>/''M''° + ''f''(BME)</big>


:::: Solving for the measured variable ''m''<sub>F</sub> normalized for ''M''°,
:::: Solving for the measured variable ''m''<sub>F</sub> normalized for ''M''°,


   <big>''m''<sub>F</sub>/''M''° = BME - ''f''(BME) + ''m''°<sub>F</sub>/''M''°             (Eq. 11)</big>
   <big>'''Eq. 11''':  ''m''<sub>F</sub>/''M''° = BME - ''f''(BME) + ''m''°<sub>F</sub>/''M''°</big>


:::: which finally shows the equation derived to plot the normalized body fat mass as a function of BME,
:::: which finally shows the equation derived to plot the normalized body fat mass as a function of BME,


   <big>''m''<sub>F</sub>/''M''° = (1-''f'')·BME + ''m''°<sub>F</sub>/''M''°                 (Eq. 12)</big>
   <big>'''Eq. 12''':  ''m''<sub>F</sub>/''M''° = (1-''f'')·BME + ''m''°<sub>F</sub>/''M''°</big>


:::: In this plot (Fig. 1), the slope equals (1-''f''), and the intercept is the fat mass normalized for the reference mass at a given height in the HRP.
:::: In this plot (Fig. 1), the slope equals (1-''f''), and the intercept is the fat mass normalized for the reference mass at a given height in the HRP.

Revision as of 10:42, 10 January 2020

Work in progress

Body fat in the healthy reference population

Lean body mass, ML [kg], is the fat-free body mass, and is thus defined as ML M-mF,
Eq. 2:  M  ML + mF
In turn, M is the sum of the reference mass at a given height and excess body mass, ME M-M°,
Eq. 3:  M  M° + ME
Excess body mass, ME, is due to accumulation of an excess fat mass, mFE, accompanied by a gain of excess lean mass, mLE, which includes increased bone mineral density, added bone mass and muscle mass due to the mechanical 'weight-lifting effect' (Iwaniec 2016 J Endocrinol). Thus Eq. 2 and 3 combined yield the definition for excess body mass,
Eq. 4:  ME  mFE + mLE
Inserting Eq. 4 into Eq. 3,
Eq. 5:  M = M° + mFE + mLE
The fat mass, mF, is defined as the sum of the reference fat mass and excess fat mass, mF m°F+mFE, hence
Eq. 6:  mFE  mF - m°F
Inserting Eq. 6 into Eq. 5 yields body mass as the sum of the reference mass minus reference fat mass (which is the reference lean mass, M°L = M-m°F), plus the total body fat mass and the excess lean mass,
Eq. 7:  M = M° - m°F + mF + mLE
Normalization for M° and considering that the body mass excess is BME=M/M°-1,
Eq. 8:  BME = mF/M° - m°F/M° + mLE/M°
The excess lean mass normalized for M° is a function of BME,
Eq. 9:  mLE/M° = f(BME)
Inserting Eq. 8 and 9 into Eq. 7.2 yields
Eq. 10:  BME = mF/M° - m°F/M° + f(BME)
Solving for the measured variable mF normalized for M°,
 Eq. 11:  mF/M° = BME - f(BME) + m°F/M°
which finally shows the equation derived to plot the normalized body fat mass as a function of BME,
 Eq. 12:  mF/M° = (1-f)·BME + m°F/M°
In this plot (Fig. 1), the slope equals (1-f), and the intercept is the fat mass normalized for the reference mass at a given height in the HRP.