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  • {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Tissue and cell::Heart]] |?Mammal and model=Organism
    464 bytes (66 words) - 14:50, 29 November 2016
  • {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Tissue and cell::Skeletal muscle]] |?Mammal and model=Organism
    474 bytes (67 words) - 14:49, 29 November 2016
  • {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Tissue and cell::Nervous system]] |?Mammal and model=Organism
    473 bytes (67 words) - 14:50, 29 November 2016

Page text matches

  • {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Tissue and cell::Heart]] |?Mammal and model=Organism
    464 bytes (66 words) - 14:50, 29 November 2016
  • ...ications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Islet cell;pancreas;thymus]] |?Mammal and model=Organism
    1 KB (209 words) - 11:31, 11 November 2016
  • {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Tissue and cell::Skeletal muscle]] |?Mammal and model=Organism
    474 bytes (67 words) - 14:49, 29 November 2016
  • {{#ask:[[Category:Abstracts]] [[Additional label::MiP2013]] [[Tissue and cell::Nervous system]] |?Mammal and model=Organism
    473 bytes (67 words) - 14:50, 29 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Stem cells]] |?Mammal and model=Organism
    1 KB (199 words) - 12:09, 9 January 2017
  • ...{#ask:[[Category:Publications]][[Was published in year::1993]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::1993]][[Instrument and method::Oxygraph-2k]]
    2 KB (276 words) - 09:22, 13 February 2020
  • ...ethod::Oxygraph-2k]] [[Tissue and cell::Endothelial;epithelial;mesothelial cell]] |?Mammal and model=Organism
    1 KB (199 words) - 11:31, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Other mammals]] |?Mammal and model=Organism
    748 bytes (100 words) - 11:15, 11 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Kidney]] |?Mammal and model=Organism
    1 KB (200 words) - 11:29, 11 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Liver]] |?Mammal and model=Organism
    1 KB (200 words) - 11:29, 11 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Fat]] |?Mammal and model=Organism
    1 KB (200 words) - 11:28, 11 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Genital]] |?Mammal and model=Organism
    1 KB (200 words) - 11:28, 11 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Blood cells]] |?Mammal and model=Organism
    1 KB (207 words) - 22:27, 29 February 2020
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Heart]] |?Mammal and model=Organism
    1 KB (205 words) - 11:29, 11 November 2016
  • |title=Sautchuk R Jr, Eliseev RA (2022) Cell energy metabolism and bone formation. https://doi.org/10.1016/j.bonr.2022.101594 ...ble methods to study energy metabolism on a subcellular, cellular, tissue, and live animal levels.
    1 KB (192 words) - 18:26, 23 November 2022
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Lymphocyte]] |?Mammal and model=Organism
    1 KB (205 words) - 18:49, 31 January 2020
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Platelet]] |?Mammal and model=Organism
    1 KB (205 words) - 09:24, 3 March 2020
  • ...2k]] [[Injury and adaptation::Mitochondrial Disease; Degenerative Disease and Defect]] |?Tissue and cell=Tissue;cell
    873 bytes (112 words) - 14:45, 10 April 2017
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Lung;gill]] |?Mammal and model=Organism
    1 KB (203 words) - 11:30, 11 November 2016
  • ...tion and anticancer immunosuppression by preserving mitochondrial function and control of autophagy. == Spermidine and mitObesity ==
    1 KB (162 words) - 14:09, 24 September 2023
  • |?Mammal and model=Organism |?Tissue and cell=Tissue;cell
    622 bytes (78 words) - 14:38, 7 March 2020
  • |?Mammal and model=Organism |?Tissue and cell=Tissue;cell
    622 bytes (78 words) - 14:38, 7 March 2020
  • |?Mammal and model=Organism |?Tissue and cell=Tissue;cell
    514 bytes (71 words) - 14:48, 29 November 2016
  • |?Mammal and model=Organism |?Tissue and cell=Tissue;cell
    755 bytes (91 words) - 07:48, 27 March 2020
  • ...ns have specific features and characteristics like the presence of keratin and resistance to polioviruses. ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::HeLa]]
    2 KB (257 words) - 16:30, 11 January 2017
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Nervous system]] |?Mammal and model=Organism
    1 KB (210 words) - 11:28, 8 June 2018
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Skeletal muscle]] |?Mammal and model=Organism
    2 KB (217 words) - 11:30, 11 November 2016
  • ...e embryo fibroblasts. The cell line has since become a standard fibroblast cell line. [http://nih3t3.com/nih3t3_cell_culture.html Cell Culture Information]
    2 KB (318 words) - 13:02, 11 January 2017
  • ...ications]] [[Instrument and method::Oxygraph-2k]] [[Injury and adaptation::Cell death]] |?Mammal and model=Organism
    1 KB (171 words) - 16:05, 4 June 2017
  • '''Chinese hamster ovary''' ('''CHO''') cells are a mammalian model cell line derived from the ovary of the Chinese hamster. ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::CHO]]
    2 KB (241 words) - 16:13, 11 January 2017
  • ...s, including arterial disease and cancer development and other endothelial cell signaling pathways). ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::HUVEC]]
    2 KB (283 words) - 11:33, 11 November 2016
  • Murine macrophage-derived cell lines: RAW 264.7, AMJ2-C11 (pulmonary alveolus of lungs) ...culturing, they adhere and function as scavengers of modified lipoproteins and dead apoptotic cells. They also produce growth factors.
    2 KB (261 words) - 11:33, 11 November 2016
  • ...tary intake of flavonoids as nutraceuticals is discussed for targeting T2D and other degenerative diseases. == Flavonoids and mitObesity ==
    1 KB (191 words) - 14:13, 24 September 2023
  • ...tissue''', including [[permeabilized muscle fibers]]: selective mechanical and chemical ([[saponin]]) permeabilization of the plasma membrane. ...ions]] [[Instrument and method::Oxygraph-2k]] [[Preparation::Permeabilized tissue]]
    2 KB (213 words) - 18:55, 15 May 2019
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[MiP area::Pharmacology;toxicology]] |?Mammal and model=Organism
    2 KB (217 words) - 08:53, 6 July 2023
  • ...les mitochondrial respiration. Rapamycin delays senescence in human cells, and extends lifespan in mice without detrimental effects on mitochondrial fitne == Rapamycin and mitObesity ==
    1 KB (154 words) - 14:10, 24 September 2023
  • ...ture. HEK 293 cells should not be used as an ''in vitro'' model for kidney cell function or studies involving kidney cells. ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::HEK]]
    2 KB (289 words) - 16:31, 11 January 2017
  • ...]] [[Organism::Human]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell type::Heart]] |?Mammal and model=Organism
    1 KB (199 words) - 16:04, 16 April 2018
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Nervous system]] [[Pathways::F]] |?Mammal and model=Organism
    2 KB (323 words) - 17:56, 16 February 2022
  • ...sage adjusted to individual body mass. It is a non-selective COX inhibitor and exerts an effect on long-chain fatty acid transport into mitochondria. == Aspirin and mitObesity ==
    1 KB (156 words) - 17:19, 24 September 2023
  • ...]] [[Organism::Human]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell type::Skeletal muscle]] |?Mammal and model=Organism
    1 KB (200 words) - 05:08, 6 February 2024
  • ...{#ask:[[Category:Publications]][[Was published in year::1997]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::1997]][[Instrument and method::Oxygraph-2k]]
    643 bytes (85 words) - 09:20, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::1996]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::1996]][[Instrument and method::Oxygraph-2k]]
    643 bytes (85 words) - 09:21, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::1995]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::1995]][[Instrument and method::Oxygraph-2k]]
    643 bytes (85 words) - 09:21, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::1994]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::1994]][[Instrument and method::Oxygraph-2k]]
    643 bytes (85 words) - 09:21, 13 February 2020
  • ...ro''. These cell lines retain the ability of differentiation into neuronal cell types on treatment with various agents. This ability of NB cells to prolife ...ll lines: LAN-1, IMR-32 (N-type) and SK-N-AS (S-type). Mouse neuroblastoma cell line: Neuro 2a.
    2 KB (318 words) - 09:07, 23 May 2018
  • {{#ask:[[Category:Publications]] [[Instrument and method::O2k-Fluorometer]] |?Mammal and model=Organism
    682 bytes (95 words) - 15:30, 10 June 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2010]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2010]][[Instrument and method::Oxygraph-2k]]
    675 bytes (87 words) - 09:15, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2009]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2009]][[Instrument and method::Oxygraph-2k]]
    675 bytes (87 words) - 09:16, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2008]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2008]][[Instrument and method::Oxygraph-2k]]
    675 bytes (87 words) - 09:16, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2007]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2007]][[Instrument and method::Oxygraph-2k]]
    672 bytes (87 words) - 09:16, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2006]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2006]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:16, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2005]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2005]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:17, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2004]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2004]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:17, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2003]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2003]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:18, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2002]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2002]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:18, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2001]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2001]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:18, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2000]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2000]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:20, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::1999]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::1999]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:20, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::1998]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::1998]][[Instrument and method::Oxygraph-2k]]
    670 bytes (87 words) - 09:20, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2011]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2011]][[Instrument and method::Oxygraph-2k]]
    675 bytes (87 words) - 09:14, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2012]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2012]][[Instrument and method::Oxygraph-2k]]
    672 bytes (87 words) - 09:14, 13 February 2020
  • ...2k]] [[Mammal and model::Human]] [[Mammal and model::Mouse]] [[Tissue and cell::Skeletal muscle]] |?Mammal and model=Organism
    2 KB (214 words) - 16:04, 16 April 2018
  • ...:Publications]] [[Instrument and method::Oxygraph-2k]] [[Additional label::Tissue normoxia]] |?Mammal and model=Organism
    1 KB (169 words) - 11:39, 21 August 2023
  • ...howed variable results. It is a cationic tetrapeptide which readily passes cell membranes, associates with [[cardiolipin]] in the mitochondrial inner membr == Elamipretide and mitObesity ==
    1 KB (180 words) - 14:14, 24 September 2023
  • ...ent [[mitochondrial preparations]], as a guide to select the best approach and to critically evaluate published results. |?Mammal and model=Organism
    767 bytes (93 words) - 09:12, 5 October 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2013]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2013]][[Instrument and method::Oxygraph-2k]]
    697 bytes (91 words) - 09:14, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2014]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2014]][[Instrument and method::Oxygraph-2k]]
    696 bytes (91 words) - 09:14, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2015]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2015]][[Instrument and method::Oxygraph-2k]]
    698 bytes (91 words) - 09:13, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2016]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2016]][[Instrument and method::Oxygraph-2k]]
    698 bytes (91 words) - 09:13, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2017]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2017]][[Instrument and method::Oxygraph-2k]]
    698 bytes (91 words) - 09:12, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2018]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2018]][[Instrument and method::Oxygraph-2k]]
    698 bytes (91 words) - 09:12, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2019]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2019]][[Instrument and method::Oxygraph-2k]]
    699 bytes (91 words) - 09:11, 13 February 2020
  • ...{#ask:[[Category:Publications]][[Was published in year::2020]][[Instrument and method::Oxygraph-2k]] {{#ask:[[Category:Publications]][[Was published in year::2020]][[Instrument and method::Oxygraph-2k]]
    699 bytes (91 words) - 09:09, 13 February 2020
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Additional label::PBMC]] |?Mammal and model=Organism
    1 KB (203 words) - 09:23, 3 March 2020
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Additional label::Leukemia]] |?Mammal and model=Organism
    1 KB (203 words) - 18:57, 31 January 2020
  • |title=Ast T, Mootha VK (2019) Oxygen and mammalian cell culture: are we repeating the experiment of Dr. Ox? Nat Metab 1:858-860. ...nvironmental parameter is so important in the design and interpretation of cell culture studies.
    991 bytes (136 words) - 17:27, 20 April 2022
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Reptiles]] |?Mammal and model=Organism
    1 KB (189 words) - 15:22, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Artemia]] |?Mammal and model=Organism
    1 KB (178 words) - 11:16, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Amphibians]] |?Mammal and model=Organism
    1 KB (178 words) - 15:22, 11 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::Ca]] |?Mammal and model=Organism
    1 KB (180 words) - 12:37, 14 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Molluscs]] |?Mammal and model=Organism
    1 KB (189 words) - 15:53, 16 April 2018
  • :::: This topic includes applications of the O2k-Fluo ([[CaG]]) and [[MiPNet15.08 TPP electrode |Ca<sup>2+</sup>-ISE]]. ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::Ca]]
    1 KB (197 words) - 16:40, 4 July 2023
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Calcium]] |?Mammal and model=Organism
    1 KB (176 words) - 14:43, 9 March 2020
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::O2k-Spectrophotometer]] |?Mammal and model=Organism
    1 KB (185 words) - 15:24, 14 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::O2k-Protocol]] |?Mammal and model=Organism
    1 KB (184 words) - 15:45, 14 November 2016
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::Supercomplex]] |?Mammal and model=Organism
    1 KB (178 words) - 11:40, 11 November 2016
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::ADP]] |?Mammal and model=Organism
    1 KB (178 words) - 15:59, 16 April 2018
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::Oxygraph-2k]] |?Mammal and model=Organism
    1 KB (184 words) - 16:29, 14 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Zebrafish]] |?Mammal and model=Organism
    1 KB (182 words) - 11:16, 11 November 2016
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::NO]] |?Mammal and model=Organism
    1 KB (182 words) - 14:33, 9 March 2020
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Birds]] |?Mammal and model=Organism
    1 KB (183 words) - 15:22, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Injury and adaptation::Hypoxia]] |?Mammal and model=Organism
    1 KB (186 words) - 16:06, 4 June 2017
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Q-junction effect]] |?Mammal and model=Organism
    1 KB (167 words) - 09:15, 23 May 2018
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::Marker enzyme]] |?Mammal and model=Organism
    1 KB (181 words) - 11:40, 11 November 2016
  • ...:Publications]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::TCA cycle and matrix dehydrogenases]] |?Mammal and model=Organism
    1 KB (190 words) - 11:40, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Plants]] |?Mammal and model=Organism
    1 KB (196 words) - 10:30, 3 August 2022
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Fatty acid]] |?Mammal and model=Organism
    1 KB (173 words) - 11:44, 11 November 2016
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::Complex III]] |?Mammal and model=Organism
    1 KB (181 words) - 11:39, 11 November 2016
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Enzyme::Uncoupling protein]] |?Mammal and model=Organism
    1 KB (181 words) - 11:40, 11 November 2016
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::ATP production]] |?Mammal and model=Organism
    1 KB (181 words) - 15:59, 16 April 2018
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Aerobic glycolysis]] |?Mammal and model=Organism
    1 KB (181 words) - 15:59, 16 April 2018
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Amino acid]] |?Mammal and model=Organism
    1 KB (181 words) - 11:25, 16 April 2018
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Cyt c]] |?Mammal and model=Organism
    1 KB (181 words) - 11:43, 11 November 2016
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Topic::Redox state]] |?Mammal and model=Organism
    1 KB (181 words) - 16:01, 16 April 2018
  • |?Mammal and model=Organism |?Tissue and cell=Tissue;cell
    548 bytes (72 words) - 12:49, 25 February 2020
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::TIP2k]] |?Mammal and model=Organism
    1 KB (194 words) - 11:50, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Human]] |?Mammal and model=Organism
    1 KB (198 words) - 11:12, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Drosophila]] |?Mammal and model=Organism
    1 KB (198 words) - 11:16, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Eubacteria]] |?Mammal and model=Organism
    1 KB (198 words) - 08:20, 1 September 2022
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Archea]] |?Mammal and model=Organism
    1 KB (198 words) - 08:20, 1 September 2022
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Additional label::PBI-Shredder]] |?Mammal and model=Organism
    1 KB (178 words) - 11:50, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Protists]] |?Mammal and model=Organism
    1 KB (198 words) - 15:23, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Hexapods]] |?Mammal and model=Organism
    1 KB (198 words) - 15:22, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Fungi]] |?Mammal and model=Organism
    1 KB (198 words) - 15:23, 11 November 2016
  • ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Annelids]] |?Mammal and model=Organism
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  • ...tions''', which is updated by [[Bioblast editorial team|Bioblast editors]] and [[Special:CreateAccount|active wiki users]]. → '''Contact: [mailto:mario. '''Number of O2k-Publications: {{#ask:[[Category:Publications]][[Instrument and method::Oxygraph-2k]] |format=count
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  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::O2k-Fluorometer]] |?Mammal and model=Organism
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  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[MiP area::Comparative MiP;environmental MiP]] |?Mammal and model=Organism
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  • ...'Fishes''' such as bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); see also [[O2k-Publications: Zebrafish ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Fishes]]
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  • ...' is used mainly for the study of developmental biology and aging research and the intact organism is a perfect model for the O2k. ...:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Mammal and model::Caenorhabditis elegans]]
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  • ...in mammals: implications for reproductive processes and infertility. Cell Tissue Res 349:795-808. https://doi.org/10.1007/s00441-012-1444-2 |journal=Cell Tissue Res
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  • ...horylation and mitochondrial function differ between human prostate tissue and cultured cells. ...nalysis are powerful tools for investigation of mitochondrial function and tissue specific metabolism.
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  • '''O2k-Workshops with OROBOROS and Sunpoint Scientific Instrument Co., Ltd.''' |?Mammal and model=Organism
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  • ...body. The BAT progenitor cell can also be substantially free of additional cell surface markers. |tissues=Skeletal muscle, Endothelial;epithelial;mesothelial cell, Fat
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  • ...M, Graier WF (2021) Survey of molecular mechanisms of hyperbaric oxygen in tissue repair. https://doi.org/10.3390/ijms222111754 ...ed both the abovementioned pathways and their role in various applications and indications.
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  • ...ications]] [[Instrument and method::Oxygraph-2k]] [[Tissue and cell::Other cell lines]] |?Mammal and model=Organism
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  • ...ROS and RNS Sources in Physiological and Pathological Conditions. Oxid Med Cell Longev 2016:1245049. |journal=Oxid Med Cell Longev
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  • ...ublications]] [[Preparation::Oxidase; Biochemical Oxidation]] [[Instrument and method::Oxygraph-2k]] |?Tissue and cell type
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  • ...and postoperative tissue samples from colorectal cancer patients. Biochem Cell Biol [Epub ahead of print]. |journal=Biochem Cell Biol
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  • The word Nematoda comes from the Greek words ''nematos'', meaning thread, and ''eidos'', meaning form. ...us located near the tail. Nematodes possess digestive, nervous, excretory, and reproductive systems, but lack a discrete circulatory or respiratory system
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  • ...l H, Kozlov AV, Wolbank S (2015) Different metabolic activity in placental and reflected regions of the human amniotic membrane. Placenta 36:1329-32. ...e, we speculate that amniotic sub-regions may have different potential for tissue regeneration, which may be crucial for clinical applications.
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  • |info='''B''' [[Lemieux 2011 Int J Biochem Cell Biol]] |?Mammal and model=Organism
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  • ...GT, Wikström M (1992) Oxygen activation and the conservation of energy in cell respiration. Nature 356:301-9. ...d for subsequent synthesis of ATP. The molecular mechanism of O2 reduction and its linkage to H+ translocation are now emerging. The bimetallic haem iron-
    968 bytes (133 words) - 11:37, 19 August 2021
  • ...etion during ordinary tissue culturing, measured with oxygen microsensors. Cell Prolif 38:257-67. |journal=Cell Prolif
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  • ...m) is obtained through mechanical micro-disruption of fresh tissue and the cell membranes are mechanically permeabilized. == Pros and cons ==
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  • ...consisting of cell cultures, clinical polyps and malignant versus healthy tissue samples. |tissues=Endothelial;epithelial;mesothelial cell
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  • ...cally]], for the exchange of soluble molecules between the cytosolic phase and external medium, without damaging the [[mitochondrial|mt]]-membranes. ...lls implies the intactness of the plasma membrane. Any typical quantiative cell viability test (trypan blue etc) evaluating the intactness of the plasma me
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  • ...ases are commonly obesity-induced. The search for the link between obesity and the etiology of diverse preventable diseases lead to the hypothesis, that m |info=[[:Category:BME_and_mitObesity |Body mass excess and mitObesity]]
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  • ...' is a natural bioactive phenol prouced by several plants with antioxidant and anti-inflammatory effects. Dietary intake as nutraceutical is discussed for == Resveratrol and mitObesity ==
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  • ...r JW, Tandler B, Hoppel CL (1977) Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle. J Biol Chem 2 ...mitochondrial types differed not only in their respective locations in the cell, but also in certain biochemical properties.
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  • |?Respiration and regulation |?Mammal and model=Organism
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  • ...regularly posted on the [[OROBOROS_INSTRUMENTS|Oroboros Ecosystem Agenda]] and disseminated in the [[Bioblast_alert |Bioblast alert circulars]]. :::: Oroboros supports the freedom to share information and chooses to highlight O2k-Publications with open-access [[Creative Commons A
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  • ...f mitochondria from cultured cells and liver tissue biopsies for molecular and biochemical analyses. Methods Mol Biol 1295:87-97. ...purification steps, the obtained mitochondrial fraction meets the quality and purity required for molecular analyses, e.g. proteomic comparisons, as well
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  • |?Mammal and model=Organism |?Tissue and cell=Tissue;cell
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  • Communicated by [[Huete-Ortega M]] and [[Gnaiger E]] (last update 2021-03-23) == Strengths and limitations ==
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  • ...chondrial function in myocardium of dogs with chronic heart failure. J Mol Cell Cardiol 30:1757-62. |journal=J Mol Cell Cardiol
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  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::TIP2k]] |?Mammal and model=Organism
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  • ...tion of PKA-targeted genes, in adipocytes and adipose tissue. Am J Physiol Cell Physiol 311:C269-76. |journal=Am J Physiol Cell Physiol
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  • ...ral limitations of blebbistatin i.e. low solubility in water, cytotoxicity and phototoxicity have been described. |?Mammal and model=Organism
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  • : » '''[[MiP2015]]''' - all abstracts in alphabetical order and programme sessions. == MiPMap - Comparative: species, tissue and cells, preparation ==
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  • ...al impact of human amniotic membrane tension on mitochondrial function and cell viability ''in vitro''. Cells 8:E1641. ...to elucidate the underlying molecular mechanisms between tissue distention and viability of hAM cells.
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  • ...2 in the afternoon, who will join in the evening for general presentations and a discussion of the conclusions. We would like to obtain your quick feedbac :::: 2A: '''Mitochondrial assays in blood cells: Blood cell preparation, cryopreservation, respiration.'''
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  • |institution=Cell and Tissue Engineering Laboratory
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  • ...horylation and mitochondrial function differ between human prostate tissue and cultured cells. https://doi.org/10.1111/febs.13733 ...nalysis are powerful tools for investigation of mitochondrial function and tissue specific metabolism.
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  • == MiPMap - Comparative: species, tissue and cells, preparation == |?Mammal and model
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  • |title=Cannon B, Nedergaard J (2008) Studies of thermogenesis and mitochondrial function in adipose tissues. Methods Mol Biol 456:109-21. ...ence on whole body metabolism, and specific properties of the mitochondria and their mode of function may be addressed using these methods.
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  • : » '''[[MiP2014]]''' - all abstracts in alphabetical order and programme sessions. == MiPMap - Comparative: species, tissue and cells, preparation ==
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  • |?Mammal and model |?Tissue and cell
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  • |?Mammal and model |?Tissue and cell
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  • ...tial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia. https://doi.org/10.1111/j.1582-4934.2011.01258.x |info=J Cell Mol Med 15:1239-53. [https://pubmed.ncbi.nlm.nih.gov/21251211/ PMID:2125121
    3 KB (443 words) - 06:52, 28 June 2022
  • ...Couto-Lima CA, Alberici LC (2016) Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized bio ...p to unravel the mechanisms that regulate mitochondrial function in health and disease.
    2 KB (292 words) - 11:16, 7 March 2020
  • ...ux in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells)- '''[[SUIT-032]]''' == Strengths and limitations ==
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  • == MiPMap - Comparative: species, tissue and cells, preparation == |?Mammal and model
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  • ...ET capacity]], as determined by measurement of oxygen consumption in ''L'' and ''E'' sequentially. The ''L/E'' coupling-control ratio is an index of [[unc |info=[[Gnaiger 2009 Int J Biochem Cell Biol]], [[Gnaiger 2020 BEC MitoPathways]]
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  • ...a, tissue homogenate and permeabilized cells) at low oxygen concentration (tissue normoxia) ...itions: 1.) under tissue normoxia (50-60 µM = [O<sub>2</sub>]), 2.) under tissue hyperoxia (> 120 µM = [O<sub>2</sub>]) or 3.) you can change the oxygen co
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  • ...ontrol are altered in a hepatic cell culture model of cancer cachexia. Mol Cell Biochem 476:23-34. |journal=Mol Cell Biochem
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  • |institution=Department of Biochemistry and Molecular Cell Biology (N30), University Medical Center Hamburg-Eppendorf, DE |keyword=Adipose Tissue Energy Metabolism
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  • ...ux in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells)- '''[[SUIT-006]]''' == Strengths and limitations ==
    2 KB (233 words) - 10:43, 26 January 2024
  • ...x in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells)- '''[[SUIT-034]]''' == Strengths and limitations ==
    2 KB (244 words) - 09:56, 26 January 2024
  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Substrate states::FAO]] |?Tissue and cell
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  • ..., criteria of integrity, and assays with reference to tissue function. Mol Cell Biochem 174:55-60. |journal=Mol Cell Biochem
    2 KB (309 words) - 01:21, 16 February 2022
  • ...evels in Standard Cell Culture Affect Oxygen-Consuming Reactions. Oxid Med Cell Longev 2018:8238459. |journal=Oxid Med Cell Longev
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  • ...es the [[O2k-Core]], [[O2k-Fluo LED2-Module]] and [[TIP2k-Module |TIP2k]], and supports all other add-on O2k-Modules of the [[Oroboros O2k]]. ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::O2k-Fluorometer]]
    3 KB (366 words) - 11:51, 14 April 2021
  • ...ned fiber techniques in studies of mitochondrial function ''in vivo''. Mol Cell Biochem 184:81-100. |journal=Mol Cell Biochem
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  • == Strengths and limitations == ...ount (''N''<sub>ce</sub>) is the sum of viable cells (''N''<sub>vce</sub>) and dead cells (''N''<sub>dce</sub>).
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  • ...'A''' '''[[SUIT-003]]''' - [[Coupling-control protocol]] and respirometric cell viability test; ce: living cells, pce: permeabilized cells == Strengths and limitations ==
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  • |info='''A''' pti: permeabilized tissue- '''[[SUIT-015]]''' == Strengths and limitations ==
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  • ...metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol 22:119-41. https://doi.org/10.1038/s41580-020-00313-x |journal=Nat Rev Mol Cell Biol
    2 KB (313 words) - 19:19, 11 October 2023
  • ...e:Carles Canto.JPG|left|90px|Carles Canto Alvarez]] Mitochondrial dynamics and cellular metabolism: lessons from mouse models. ...use of cultured cell lines, and the role of different mitochondrial fusion and fission regulators in differentiated tissues remains unclear.
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  • ...|left|90px]] Oscillations in mitochondrial ROS production during the early cell cycles in Xenopus embryos. ...related to the cell cycle and its relevance for the early development and tissue regeneration.
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  • ...ux in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells)- '''[[SUIT-033]]''' == Strengths and limitations ==
    2 KB (238 words) - 09:57, 26 January 2024
  • ...003]]''' Second version of the Coupling-control protocol and respirometric cell viability test '''(CCV protocol)''' == Strengths and limitations ==
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  • ...6) Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue. Cell Rep 17:1008-21. |journal=Cell Rep
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  • ...etion prevents obesity-related disorders by increasing vascular metabolism and growth. Elife 7:e39780. ...othelial metabolic and angiogenic adaptations in response to high-fat diet and a contribution of the endothelium to whole-body energy homeostasis.
    2 KB (277 words) - 10:32, 29 July 2019
  • ...ling-control protocol and Crabtree effect test -'''[[SUIT-003]]''' complex cell [[coupling-control protocol]] Communicated by [[Komlodi T ]], [[Garcia-Souza LF]], [[Cardoso LHD]] and [[Gnaiger E]] (last update 2019-04-03)
    3 KB (377 words) - 16:11, 21 September 2020
  • ...tion is linked to distinct systemic effects on lipid metabolism in humans. Cell Metab 23:1200-6. |journal=Cell Metab
    2 KB (264 words) - 09:27, 1 December 2021
  • |title=Aisenberg AC (1961) The glycolysis and respiration of tumors. Academic Press 224 pp. ...r knowledge of metabolism and biochemistry of tumors has found a competent and critical evaluation in this book
    2 KB (322 words) - 11:27, 23 September 2021
  • ...ptide signals cell non-autonomous mitochondrial unfolded protein response. Cell Res 26:1182-96. |journal=Cell Res
    1 KB (202 words) - 02:50, 1 March 2020
  • ...ategory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::TPP]] ...[[Category:Abstracts]] [[Instrument and method::Oxygraph-2k]] [[Instrument and method::TPP]]
    1 KB (198 words) - 09:21, 23 May 2018
  • ...MJ, Hagenbuchner J (2022) The complex interplay between mitochondria, ROS and entire cellular metabolism. Antioxidants (Basel) 11:1995. doi: 10.3390/anti ...between mitochondrial and entire cell physiology, including signaling from and to mitochondria.
    2 KB (285 words) - 15:46, 4 August 2023
  • ...on and regulation]]''' - Oxygen kinetics, oxygen dependence of respiration and other mitochondrial functions ...tegory:Publications]] [[Instrument and method::Oxygraph-2k]] [[Respiration and regulation::Oxygen kinetics]]
    1 KB (191 words) - 12:21, 7 March 2020
  • ...experiment may involve various [[assay]]s, ''e.g.'', a respirometric assay and an assay for protein determination. ...to the meaning of [[study]] design. A distinction made between experiment and [[study]] may be useful.
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  • ...K/OXPHOS coupling-control ratio combines the effects of coupling (''L/E'') and limitation by the phosphorylation system (''P/E''); ''L/P'' = (''L/E'') / ( |info=[[Gnaiger 2009 Int J Biochem Cell Biol]], [[Gnaiger 2020 BEC MitoPathways]], [[BEC 2020.1]]
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  • {{#ask:[[Category:Publications]] [[Instrument and method::O2k-Protocol]] [[Additional label::O2k-Demo]] [[Additional label::O |?Tissue and cell
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  • For specific chapters, see [[O2k-Procedures]] and [[O2k-Manual]]. {{#ask:[[Category:Publications]] [[Instrument and method::O2k-Protocol]]
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  • ...sment of mitochondrial function in a few milligrams of permeabilized liver tissue, without isolation of mitochondria. This provides a basis for the analysis |keywords=Mitochondrial respiration, Pig liver tissue, Cell membrane permeabilization, Cold ischemia, Mitochondrial injury
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  • # [[Property:Mammal and model]] # [[Property:Tissue and cell]]
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  • ...of the versatility of mitochondrial function in response to physiological and pathological challenges, indicating metabolic reprogramming of mitochondria == References and Support ==
    4 KB (491 words) - 19:17, 10 January 2022
  • ...ension composed of mitochondria from multiple sub-populations from various cell types, making physiological interpretations challenging. Therefore, the cur ...rial function in the mouse brain with both acute and chronic perturbations and compared our results with the traditional isolated mitochondria preparation
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  • |info='''A''' '''[[SUIT-003]]''' - [[Coupling-control protocol]] and [[Crabtree effect]] == Strengths and limitations ==
    2 KB (366 words) - 16:05, 21 September 2020
  • |info='''A''' [[Coupling-control protocol]] and [[Crabtree effect]] with glycolysis inhibition- '''[[SUIT-003]]''' == Strengths and limitations ==
    2 KB (337 words) - 16:03, 24 November 2022
  • ...ubcutaneous white adipose tissue in humans after severe adrenergic stress. Cell Metab 22:219-27. |journal=Cell Metab
    2 KB (277 words) - 10:54, 31 March 2021
  • ...rotocol for measuring respiratory function of mitochondria in frozen colon tissue from rats. https://doi.org/10.1016/j.xpro.2023.102560 ...ilitates the retrospective analysis of mitochondrial respiration in frozen tissue.
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  • ...n mitochondrial preparations; mt: isolated mitochondria, tissue homogenate and permeabilized cells Communicated by [[Komlodi T]] and [[Gnaiger E]] (last update 2019-06-06)
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  • ...human subcutaneous adipose-derived stem cells isolated from healthy young and old individual. Mitochondr Physiol Network 28.02 ...isolated from abdominal subcutaneous white adipose tissue (scWAT) from old and young individuals.
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  • ...ical normoxia for improved translation of cell physiology to animal models and humans. https://doi.org/10.1152/physrev.00041.2017 ...n of findings under physiological conditions in vitro to disease pathology and the design of novel therapeutics.
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  • ...nance the integrity of the tissue. Study the capturing capacity of glucose and in other way the FA could be very interesting for complete my data. ...mmon in European population and the other (J) related with a low incidence and progression of the pathology.
    2 KB (269 words) - 12:00, 15 January 2018
  • |title=Schafer FQ, Buettner GR (2001) Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione ...ellular mechanisms associated with cell growth and development, signaling, and reductive or oxidative stress.
    2 KB (300 words) - 12:34, 31 May 2019
  • ...ctionality of isolated mitochondria, additionally taking into account time and cost requirements of the procedure. ...ssue. It is pivotal that during the entire isolation procedure the samples and buffers are kept on ice.
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  • ...er insulin sensitivity differently affects mitochondrial coupling in liver and muscle cells. ...is any cell type specific difference that could potentially be ascribed to tissue specific mechanisms of IR.
    4 KB (548 words) - 11:53, 7 October 2019
  • ...d by NADH fluorescence: from animal models to human studies. Am J Physiol Cell Physiol 292:C615-40. |journal=Am J Physiol Cell Physiol
    2 KB (317 words) - 10:58, 4 February 2022
  • Communicated by [[Doerrier C]], [[Komlodi T]], [[Huete-Ortega M]] and [[Gnaiger E]] (last update 2019-06-05) == Strengths and limitations ==
    2 KB (252 words) - 11:07, 17 September 2020
  • ...s been designed to test the mitochondrial respiration at low oxygen levels and to modify the oxygen concentration in the same protocol. To decrease or inc == Strengths and limitations ==
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  • ...hite adipose tissue cells, and the use of said brown/beige adipocytes in a cell based therapy of a subject or in screening platforms.
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  • |title=UCP3-related changes in brown and brite/beige adipose tissue in cold-acclimated mice. ...ss upon cold acclimation [2]. The function and regulation of UCP3 in brown and brite/beige adipose tissues is unknown.
    3 KB (400 words) - 10:58, 4 September 2015
  • ...le=Ling C, Rönn T (2019) Epigenetics in human obesity and type 2 diabetes. Cell Metab 29:1028-44. https://doi.org/10.1016/j.cmet.2019.03.009. |journal=Cell Metab
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  • ...issue and cell: Skeletal muscle|Skeletal muscle]] ••• [[MiP2013 Tissue and cell: Nervous system|Brain;Nervous system]]''' ...13 Stress: Hypoxia|Hypoxia]]''' - High-altitute mitochondrial physiology and hypoxia (supported by COST project HypoxiaNet for members of [http://www.hy
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  • ...hansson F, Zwahlen M, von Heijne G, Nielsen J, Pontén F (2015) Proteomics. Tissue-based map of the human proteome. Science 347:1260419. ...as well as navigation of global expression patterns, in all major tissues and organs in the human body.
    2 KB (323 words) - 10:00, 30 June 2015
  • ...ress responses independently of respiratory chain deficiency in the heart. Cell Metab 19:458-69. |journal=Cell Metab
    2 KB (285 words) - 15:05, 3 February 2021
  • ...Baes M, Carmeliet P (2009) Oxygen sensors at the crossroad of metabolism. Cell Metab 9:11-22. |journal=Cell Metab
    1 KB (162 words) - 21:39, 11 April 2022
  • ...pose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metab 17:210-24. |journal=Cell Metab
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  • == Strengths and limitations == ...mparison of respiratory control in a large variety of species, tissues and cell types. Both SUIT protocols provide a mitochondrial mapping which allows:
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  • ...these novel findings, succinate and CII are promising targets for treating and preventing PCa. |preparations=Permeabilized tissue
    2 KB (313 words) - 18:32, 3 November 2022
  • ...cher R, Kriváková P, Lotkova H, Milerová M, Drahota Z, Cervinková Z (2009) Tissue specific sensitivity of mitochondrial permeability transition pore to Ca<su ...specific strategies of cell protection against induction of the apoptotic and necrotic processes.
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  • |title=PPM1K, novel insights in connecting metabolism and autophagy in the heart. ...be highly expressed in cardiac tissue besides low BCAA catabolism levels, and its ablation leads to cardiac impairment. Thus, we are now testing the hypo
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  • ...ratio''' is the ratio of (partially coupled) [[ROUTINE respiration]] ''R'' and (noncoupled) [[ET capacity]] ''E''. The ''R/E'' control ratio is an expres ...'E'' by limitation of oxidative capacity by defects of substrate oxidation and complexes of the ET pathway. The corresponding inverse ratio is the uncoupl
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  • Communicated by [[Huete-Ortega M]] and [[Gnaiger E]] (last update 2021-03-23) == Strengths and limitations ==
    2 KB (247 words) - 12:45, 23 March 2021
  • ...and mouse brown adipose tissue mitochondria have comparable UCP1 function. Cell Metab 24:246-55. |journal=Cell Metab
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  • .... NS indicates respiration with a cocktail of substrates supporting the N- and S-pathways. |info=[[Gnaiger 2009 Int J Biochem Cell Biol]], [[Gnaiger 2020 BEC MitoPathways]]
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  • == Strengths and limitations == ...mparison of respiratory control in a large variety of species, tissues and cell types. Both SUIT protocols provide a mitochondrial mapping which allows:
    3 KB (361 words) - 12:15, 2 December 2021
  • ...ing isolated mitochondria from the cytotrophoblast and syncytiotrophoblast cell lineages of the placenta we established that although both mitochondrial po
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  • ...a-RovesP.jpg|left|90px|Pablo Miguel Garcia-Roves]] Mitochondrial signature and lifestyle modulation of metabolic plasticity. ...tissue or organism to modify its metabolism under different physiological and pathological conditions.
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  • Communicated by [[Cardoso LHD]], [[Antunes D]] and [[Gnaiger E]] (last update 2019-07-31) == Strengths and limitations ==
    2 KB (236 words) - 12:40, 17 September 2020
  • ...e tissue with disruption of the regulator of G protein signaling 14. Aging Cell 17:e12751. |journal=Aging Cell
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  • ...ntrol_state|F-pathway]] in [[LEAK respiration#The_LEAK_state |LEAK state]] and [[Oxidative phosphorylation|OXPHOS state]]''' ...] and [[FNS]] in [[Oxidative phosphorylation|OXPHOS state]] and of [[FNS]] and [[S]] in [[ET capacity| ET state]] can be evaluated. SUIT-015 can be extend
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  • ...tute the adipogenic differentiation process. Due to the implication in the cell differentiation process of the oxidative phosphorylation system (OXPHOS), a ...nhibitors. The chosen compounds were rotenone (10 nM), antimycin A (10 nM) and oligomycin (16 nM), each one of them separately assayed. The obtained resul
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  • ...aque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics. Atherosclerosis 268:1-11. ...efects in mitochondrial respiration exist in human atherosclerotic plaques and to identify the appropriate markers that may reflect a switch in VSMC energ
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  • |institution=Department of Medical Cell Biology, Research Group Fredrik Palm AND
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  • ...the effects of Orexin-A on thermogenesis in human deep neck brown adipose tissue. Int J Obes (Lond) 41:1646-53. ...n-A (OX-A) in humans. OX-A increases thermogenesis in rodent brown adipose tissue (BAT), yet this phenomenon has not been explored in humans.
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  • Communicated by [[Huete-Ortega M]] and [[Gnaiger E]] (last update 2021-03-23) == Strengths and limitations ==
    2 KB (263 words) - 12:46, 23 March 2021
  • ...cient stem cells uniformly give rise to brown-type adipocytes ''in vitro'' and ''in vivo''. Furthermore, brown fat programming of mesenchymal stem cells b |tissues=Other cell lines
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  • mitochondrial DNA (mtDNA) in several tissues and cell types with regard to different mitochondrial associated disorders. ...on system (OXPHOS). Consequently an impairment of the biochemical activity and integrity of the cells occurs.
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  • == Strengths and limitations == ...ell [[coupling-control protocol]] that provides information on [[ROUTINE]] and [[Electron transfer pathway]] in the presence of ([[MitoKit-CII/Succinate-n
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  • ...ub>2</sub>O<sub>2</sub> (AmR) for isolated mitochondria, tissue homogenate and permeabilized cells ...H<sub>2</sub>O<sub>2</sub> production) changes over the experimental time and upon addition of chemicals. To correct H<sub>2</sub>O<sub>2</sub> flux for
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  • ...ls, enable towards the therapeutic use of stem cell for tissue engineering and regenerative medicine.
    2 KB (299 words) - 23:07, 15 July 2022
  • ...es cigarette smoke-induced lung dysfunction and tissue damage. Am J Respir Cell Mol Biol 60:515-22. |journal=Am J Respir Cell Mol Biol
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  • ...essment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells. Nat Protoc 7:1235-46. ...nts in a narrow concentration range allow maximal sensitivity, specificity and linearity of the kinetics. This protocol can be completed in 3 h.
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  • ...wgard CB, Casey PJ, Wang M (2019) Respiratory capacity and reserve predict cell sensitivity to mitochondria inhibitors: mechanism-based markers to identify ..., that metformin and AMP kinase inhibition synergistically suppress cancer cell proliferation.
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  • ...ocol]] Reference protocol RP1 for isolated mitochondria, tissue homogenate and permeabilized cells''' == Strengths and limitations ==
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  • ...d antiretroviral therapy have divergent effects on mitochondria in adipose tissue. J Infect Dis 205:1778-1787. ...ve evaluations of their effects on mitochondria in muscle, adipose tissue, and blood cells are limited.
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  • Communicated by [[Cardoso LH]], [[Komlodi T]] and [[Gnaiger E]] (last update 2019-07-03) == Strengths and limitations ==
    2 KB (244 words) - 09:00, 17 September 2020
  • == List of publications: OXPHOS and ET pathway == ::: '''» OXPHOS and ET-pathway'''
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  • |preparations=Permeabilized cells, Permeabilized tissue, Isolated mitochondria == Affiliations and support ==
    2 KB (196 words) - 12:30, 3 November 2018
  • == Strengths and limitations == ...ount (''N''<sub>ce</sub>) is the sum of viable cells (''N''<sub>vce</sub>) and dead cells (''N''<sub>dce</sub>).
    3 KB (447 words) - 23:48, 12 April 2021
  • Communicated by [[Garcia-Souza LF]], [[Komlodi T]] and [[Gnaiger E]](last update 2019-06-26) == Strengths and limitations ==
    2 KB (309 words) - 13:44, 7 July 2020
  • ...G, Irving BA (2023) Impact of maximal exercise on immune cell mobilization and bioenergetics. https://doi.org/10.14814/phy2.15753 ...re needed to characterize further maximal exercise's true impact on immune cell bioenergetics.
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  • == Strengths and limitations == ...the following protocols are recommended: [[SUIT 003 AmR ce D058]] with AmR and [[SUIT 003 AmR ce D059]] with carrier titration as a control. These two pro
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  • ...ocol]] Reference protocol RP2 for isolated mitochondria, tissue homogenate and permeabilized cells''' Communicated by [[Doerrier C]] and [[Gnaiger E]] (last update 2019-09-24)
    4 KB (508 words) - 18:44, 5 March 2024
  • ...titration of digitonin, since the mitochondrial outer membrane is affected and [[cytochrome c|cytochrome ''c'']] can be released. Therefore, it is recomme == Strengths and limitations ==
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  • ...zes the reduction of cytochrome ''c'' by oxidation of [[coenzyme Q]] (CoQ) and the concomitant [[Proton pump|pumping of 4 protons]] from the cathodic (neg |?Mammal and model
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  • ...during mitochondrial remodeling and their impact on metabolic adaptation. Cell Rep 36:109565. |journal=Cell Rep
    2 KB (307 words) - 17:33, 24 September 2021
  • ...ng L, Matsumoto M, Iwata K, Umemura A, He F (2023) Reactive oxygen species and NRF2 signaling, friends or foes in cancer? Biomolecules 13:353. https://doi ...rug detoxification enzymes, contributes to cancer development, metastasis, and anticancer therapy resistance.
    2 KB (316 words) - 00:30, 18 December 2023
  • ...6%, rather than 20.9% or 20%, as commonly stated in research publications. And this is strictly only valid for incubators at sea level.
    1 KB (194 words) - 22:18, 15 July 2022
  • |title=Brennan CM, Breen EP, Porter RK (2006) Cold acclimation and oxygen consumption in the thymus. Biochim Biophys Acta 1757:1463-8. ...hat cold-acclimation only increased the amount of UCP 1 per gram of thymus tissue not, vert, similar 1.2-fold. Taken together, we conclude that UCP 1 does no
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  • ...the effects of coupling (''L/E''), physiological control of energy demand, and limitation by the OXPHOS capacity. = List of publications: LEAK and ROUTINE =
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  • ...adaptations in preeclampsia associated with progression to term delivery. Cell Death Dis 9:1150. |journal=Cell Death Dis
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  • ...FM (2020) Mitochondrial metabolism elucidated by rapid fractionation from tissue. PhD Thesis 298. ...respiration. Data is presented on how the method optimisation was analysed and developed. This largely reduced time frame gives the advantage over other m
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  • ...capacity in RAW 264.7 and Mafb/C-Maf deficient macrophage lineages. J Clin Cell Immunol 6:1-11. ...glycolytic-metabolism-is-differentially-coupled-to-proliferative-potential-and-morphodynamic-capacity-2155-9899-1000292.php?aid=38193 Open Access]
    3 KB (473 words) - 18:35, 20 March 2018
  • == Strengths and limitations == ...ol to assess just respiration since rotenone is not added at the beginning and does not prevent the inhibitory effect of oxaloacetate on the succinate deh
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  • ...ss and biogenesis triggered by an altered calcium homeostasis. Indeed, BSM cell proliferation was decreased ''in vitro'' by the calcium channel blocker gal ...s with severe wheezing, with special attention to the role of mitochondria and calcium signaling.
    3 KB (376 words) - 14:58, 20 October 2021
  • == Strengths and limitations == ...ell [[coupling-control protocol]] that provides information on [[ROUTINE]] and [[Electron transfer pathway]] in the presence of ([[MitoKit-CII/Succinate-n
    3 KB (360 words) - 11:04, 26 April 2021
  • == Manuscript table and figure blocks == ::::* Section: Workflow # and Title
    5 KB (614 words) - 23:55, 25 January 2021
  • Communicated by [[Komlodi T]] and [[Gnaiger E]] (last update 2021-11-09) == Strengths and limitations ==
    2 KB (278 words) - 09:38, 9 November 2021
  • ...-Set.JPG|180px|right]]'''PBI-Shredder O2k-Set''': Auxiliary O2k-Tool for [[tissue homogenate]] preparation ...e., safety information, product use limitations and warranty information, and the Product Specification Sheet by Pressure BioSciences Inc (PBI): [[MiPNet
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  • ...adipocyte size estimates and their association with obesity-related traits and mitochondrial function. Int J Obes (Lond) [Ephub ahead of print]. ..., we were interested to investigate the relationship between fat cell size and adipocyte mitochondrial respiratory chain capacity.
    3 KB (361 words) - 13:53, 21 July 2021
  • |info='''B''': CCP(P) and cell membrane permeability test with succinate - [[SUIT-003]] ...toPedia: SUIT]]''' - [[coupling-control protocol]] (CCP) with pyruvate and cell membrane permeability test
    3 KB (505 words) - 00:09, 13 April 2021
  • ...of [[assay]] (e.g. for measurement of respiration and enzyme activities), and (ii) a number of [[repetitions]], ''n'', of the same assay on the same samp {{MitoPedia O2k and high-resolution respirometry
    886 bytes (124 words) - 05:54, 19 July 2022
  • ...control of [[Fatty_acid_oxidation_pathway_control_state|F]], F(N), [[FN]] and [[FNS]] pathways in OXPHOS state can be evaluated by using this SUIT protoc ...ochondria|isolated mitochondria]], [[Tissue homogenate|tissue homogenate]] and [[Permeabilized cells|permeabilized cells]] (already permeabilized when the
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  • ...[living cells]] with cell permeable compounds [[MitoKit-CII/Succinate-nv]] and [[MitoKit-CII/Malonate-nv]] - [[SUIT-003 O2 ce D060]] ...of the plasma membrane-permeable succinate ([[MitoKit-CII/Succinate-nv]]) and plasma membrane-permeable malonate ([[MitoKit-CII/Malonate-nv]]) in living
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  • ...ed mtROS emission increased following 1-week HFD in eWAT, while both lipid and carbohydrate-supported mtROS were increased at 8 weeks in both depots. Comb ...t diet, Insulin resistance, Mitochondrial function, Obesity, White adipose tissue
    3 KB (363 words) - 18:52, 28 July 2023
  • ...otocol]] in the [[N-pathway]] for isolated mitochondria, tissue homogenate and cells permeabilized before addition to the O2k chamber. Communicated by [[Cardoso LHD]], [[Komlodi T]] and [[Gnaiger E]] (last update 2019-06-28)
    2 KB (336 words) - 23:38, 12 April 2021
  • ...rgan dissection, tissue analysis and morphological studies with both optic and electron microscopes. ...ertificate in computing. Her preferred creative mediums are mosaics, tiles and silks.
    2 KB (220 words) - 13:48, 12 May 2014
  • ...A (2011) Morphological and functional characterization of human cells from tissue coming from epileptic patients under surgery. Int J Dev Neurosci 29:121-9. ...ce to antiepileptic drugs, as well as to studies on plasticity, maturation and possible neurite emission for graft studies.
    2 KB (332 words) - 09:13, 11 October 2016
  • ...s and suggest the existence of varying cellular energy metabolism profiles and their kinetics among small populations of cells. The technology represents
    2 KB (265 words) - 09:23, 23 April 2018
  • ...lycerol-3-phosphate dehydrogenase by α-tocopheryl succinate. Int J Biochem Cell Biol 53:409-13. |journal=Int J Biochem Cell Biol
    2 KB (311 words) - 11:28, 8 November 2016
  • ...M, Marchingo JM, Singh F, Bray SE, Wilson J, Love AG, Swamy M (2021) IL-15 and PIM kinases direct the metabolic programming of intestinal intraepithelial ...hr kinases PIM1 and PIM2, which are essential for IEL to proliferate, grow and upregulate granzyme B in response to inflammatory IL-15. Notably, IEL from
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  • ...chondrial dysfunction, apoptosis and inflammation in brown adipose tissue, and accumulation of visceral obesogenic fat. ...rized the effect of prolonged cold exposure on BAT mitochondrial function, tissue infiltration with immune cells, apoptosis as well as mouse whole body compo
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  • ...n ATGL-mediated lipolysis in cardiac muscle, but not brown adipose tissue. Cell Metab 26:753-63. |journal=Cell Metab
    2 KB (275 words) - 12:27, 29 May 2018
  • ...unction does not mimic or enhance the adaptations to intermittent fasting. Cell Rep 14:2068-75. |journal=Cell Rep
    2 KB (269 words) - 17:00, 9 November 2017
  • ...a A (2011) Long noncoding RNAs are generated from the mitochondrial genome and regulated by nuclear-encoded proteins. RNA 17:2085-93. ...lncRNAs form intermolecular duplexes and that their abundance is cell- and tissue-specific, suggesting a functional role in the regulation of mitochondrial g
    1 KB (200 words) - 18:59, 16 January 2021
  • ...f mitochondrial electron transport chain flux and apoptosis. Int J Biochem Cell Biol 121:105704. |journal=Int J Biochem Cell Biol
    3 KB (383 words) - 10:22, 10 March 2020
  • ''Ren'' may be higher than ''Rox''. Correspondingly, Q and NAD are not fully oxidized in the REN state compared to the ROX state. ...inguished from the [[ROX]] state. However, in novel applications (Q-Module and NADH-Module), a distinction of these states is necessary. Care must be take
    2 KB (325 words) - 08:35, 25 November 2023
  • ...cell, tissue or body and the measure of an oxidant event in body fluids or tissue specimen can only be the sum of non-separatable events, sometimes of opposi
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  • ...spiratory mitochondrial function in skinned muscle fibers of human cardiac tissue. ...xidative Phosphorylation, Cell Physiological Phenomena, Myocytes, Cardiac, Cell Respiration
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  • {{#ask:[[Category:Publications]] [[Instrument and method::Oxygraph-2k]] [[Nonmammal::Plants]] {{#ask:[[Category:Abstracts]] [[Instrument and method::Oxygraph-2k]] [[Nonmammal::Plants]]
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  • ...vakaruni AS, MookerjeecS, Treberg JR, Brand MD (2010) Mitochondrial proton and electron leaks. Essays Biochem 47: 53–67. ...proton and electron leak as therapeutic targets in body weight regulation and insulin secretion.
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  • |title=The molecular transducers of physical activity consortium (MoTrPAC) and MitoEAGLE: exercise effects on mitochondria. ...ze with MitoEAGLE to provide novel insights about the role of mitochondria and exercise in human health.
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  • ...mitochondria irrespective of the species providing the specimen and of the cell type examined. ...ochondria the cristae are perpendicular to the long axis of the organelles and occur in series within which they lie parallel to one another at more or le
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  • ...>2</sub> flux and H<sub>2</sub>O<sub>2</sub> flux in isolated mitochondria,tissue homogenate or permeabilized cells''' ...to evaluate H<sub>2</sub>O<sub>2</sub> flux in the NS-pathway in the LEAK and OXPHOS states. To decrease or increse the oxygen concentration in the O2k-C
    5 KB (778 words) - 23:47, 12 April 2021
  • ...intracellular ''p''<sub>O<sub>2</sub></sub> to the level of intracellular tissue normoxia requires lowering the ambient ''p''<sub>O<sub>2</sub></sub> of the
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  • |info=[[Gnaiger 2009 Int J Biochem Cell Biol]], [[Gnaiger 2020 BEC MitoPathways]] = List of publications: S and NS pathway control states =
    1 KB (163 words) - 18:28, 1 January 2021
  • ...'' is used for the number of [[primary sample]]s taken from a study group, and the symbol ''n'' is used for the number of subsamples studied as technical {{MitoPedia O2k and high-resolution respirometry
    6 KB (956 words) - 16:48, 21 February 2024
  • ...] and [[FNS]] in [[Oxidative phosphorylation|OXPHOS state]] and of [[FNS]] and [[S]] in [[ET capacity| ET state]] is evaluated. ...ty in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells)
    2 KB (325 words) - 23:49, 12 April 2021
  • |title=Hoek JB, Cahill A, Pastorino JG (2002) Alcohol and mitochondria: a dysfunctional relationship. Gastroenterology 122:2049-63. h ...crotic cell death in response to otherwise benign or beneficial challenges and contribute to the onset or progression of alcohol-induced liver diseases.
    2 KB (305 words) - 11:14, 12 July 2023
  • :::: '''MitoEAGLE data repository for blood cells and clutured cells''' ::::» [[WG4 MitoEAGLE data: blood and cultured cells |WG4 Action]]
    3 KB (390 words) - 16:47, 12 January 2018
  • ...ile:SchlattnerU.jpg|right|150px|Uwe Schlattner]] Laboratory of Fundamental and Applied Bioenergetics, French National Institute of Health and Medical Research (INSERM),
    2 KB (231 words) - 08:20, 29 August 2022
  • |info=Methods Cell Biol 155:273-93. [https://www.ncbi.nlm.nih.gov/pubmed/32183962 PMID: 321839 |journal=Methods Cell Biol
    2 KB (286 words) - 07:17, 28 June 2022
  • == Strengths and limitations == ...llows to analyse the presence of ATPases in [[mitochondrial preparations]] and is useful as a quality control of the sample preparation.
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  • ...urrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes. Biochem Biophys Rep 4:111-25. ...re considerably (by almost 3 times) lower in comparison with healthy colon tissue cells (256±34 µM).
    3 KB (394 words) - 15:57, 7 November 2016
  • ...mitochondrial respiration in the developing mouse brain is sex-, age- and tissue-dependent. Respir Physiol Neurobiol 266:156-62. ...te to a better understanding of the sex-dependent maturation of the cortex and the cardiorespiratory network located in the brainstem.
    3 KB (358 words) - 13:59, 12 June 2019
  • ..., Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704. ...tilization of fatty acids could be exploited to establish novel diagnostic and therapeutic strategies.
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  • ...ry to determine CIV activity, in which case the instrumental O2 background and chemical background may be combined in an overall correction term. |?Mammal and model=Organism
    2 KB (319 words) - 07:57, 25 November 2023
  • ...RM, Laranjinha J, Ledo A (2018) Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices. A ...m that better represents the in vivo conditions than isolated mitochondria and/or cells.
    3 KB (366 words) - 06:14, 20 April 2020
  • ...ssociated with mitochondrial dysfunction and exercise intolerance in mice. Cell Rep 17:527-40. |journal=Cell Rep
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  • ...stigaton on the role of the mitochondiral deacetylase Sirtuin 3 in adipose tissue. == Affiliations and Support ==
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  • |title=[[File:PecinovaA.JPG|left|90px|Pecinova A]] Targeting tumor cell proliferation by inhibition of mitochondrial metabolic pathways. ..., solely the metformin treatment led to profound decrease of proliferation and increased apoptosis, compared to control cells.
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  • |info='''A: simultaneous determination of O2 flux and mt-membrane potential''' ...itochondria and tissue homogenate. The protocol can be applied to cells or tissue types that display a preference for [[GM-pathway_control_state |GM]] over [
    5 KB (697 words) - 15:58, 8 June 2020
  • ...r E (2012) The PBI-Shredder - an auxiliary HRR-tool for the preparation of tissue homogenates for diagnosis of mitochondrial respiratory function. Mitochondr ...e.g. heart, liver, brain) with high reproducibility of mitochondrial yield and mitochondrial function as evaluated with HRR.
    5 KB (651 words) - 18:25, 10 January 2022
  • ...P) with plasma membrane-permeable succinate ([[MitoKit-CII/Succinate-nv]]) and plasma membrane-permeable malonate ([[MitoKit-CII/Malonate-nv]]) in living Communicated by [[Garcia-Souza LF]], [[Cardoso LHD]] and [[Gnaiger E]] (last update 2019-09-24)
    3 KB (491 words) - 14:34, 27 April 2021
  • ...chondria separated from a tissue or cells by breaking the plasma membranes and attachments to the cytoskeleton, followed by centrifugation steps to separa ...[[MiPNet11.05 imt-pti-pce |Isolated mitochondria or permeabilized tissues and cells]]
    899 bytes (101 words) - 11:02, 10 April 2022
  • ...a-Alves L, Carvalho DP, Ketzer LA, Corrêa da Costa VM (2019) Brown adipose tissue remodeling induced by corticosterone in Wistar male rats. Exp Physiol 104:5 ...coid excess induced an extensive remodeling of interscapular brown adipose tissue, resulting in a white-like phenotype in association with metabolic disturba
    3 KB (367 words) - 12:30, 14 August 2019
  • ...ux in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells)-'''[[SUIT-018]]''' ...normoxia; [O<sub>2</sub>]< ~70-80 µM) oxygen concentration, or keep within tissue normoxia. A further recommendation is to reduce the oxygen concentration in
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  • |?Mammal and model |?Tissue and cell
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  • ...ediated fibroblast dysfunction and matrix remodeling to impair muscle stem cell function. Stem Cells 34:732-42. ...roadly, provide insight into the influence of the native myomatrix on stem cell behavior.
    3 KB (348 words) - 15:47, 9 November 2016
  • ...xercise-induced lipokine that increases skeletal muscle fatty acid uptake. Cell Metab 27:1111-20. |journal=Cell Metab
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  • ...structural and functional organization of mitochondrial respiratory chain and ATP synthasome as supercomplexes in human BC. |tissues=Heart, Endothelial;epithelial;mesothelial cell
    3 KB (388 words) - 17:45, 7 November 2016
  • Communicated by [[Komlodi T]], [[Garcia-Souza LF]] and [[Gnaiger E]] (last update 2019-06-24) == Strengths and limitations ==
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  • ...he conventional hypothesis of metabolic regulation of the oxygen supply to tissue. ...stitial PO2, Oxygen disappearance curve, Phosphorescence quenching method, Cell PO2 gradient
    2 KB (341 words) - 17:11, 3 March 2015
  • ...sensitivity contribute to redox stress in senescent human skeletal muscle. Cell Rep 22:2837–48. |info=[http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30264-X Open Access]
    2 KB (301 words) - 13:29, 7 March 2020
  • ...id-induced disruption of mitochondrial functions in intact cell systems. J Cell Biochem 119:7678-86. |journal=J Cell Biochem
    2 KB (290 words) - 11:11, 3 March 2020
  • ...tal and breast cancer clinical material is regulated differently. Oxid Med Cell Longev 2017:1372640. |journal=Oxid Med Cell Longev
    3 KB (388 words) - 18:43, 16 January 2021
  • ...di R, Pozzan T (2012) Mitochondrial Ca²⁺ homeostasis: mechanism, role, and tissue specificities. Pflugers Arch 464:3–17. ...ncbi.nlm.nih.gov/22706634-mitochondrial-ca2-homeostasis-mechanism-role-and-tissue-specificities/?from_single_result=10.1007%2Fs00424-012-1122-y PMID: 227066
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  • ...t of acute exercise on peripheral blood mononuclear cells nutrient sensing and mitochondrial oxidative capacity in healthy young adults. Physiol Rep 9:e15 ...hile concomitantly increasing PBMC mitochondrial oxidative capacity at the tissue level, rather than acutely changing mitochondrial oxidative capacity at the
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  • ...er with either ROS production (AmR), mt-membrane potential (TMRM, Safranin and Rhodamine 123), Ca<sup>2+</sup> (CaG) or ATP production (MgG). ...www.oroboros.at/index.php/product/o2k-fluorespirometer/ '''Product details and purchase information''']
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  • |title=Regulation of mitochondrial respiration and apoptosis by cytochrome c phosphorylation. ...brane potential, a known cause of reactive oxygen species (ROS) production and trigger of apoptosis.
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  • == Strengths and limitations == ...washing is required after the experiment to avoid carry-over of uncoupler and inhibitors, if used.
    2 KB (290 words) - 23:58, 12 April 2021
  • ...4) Regulators of mitochondrial Ca2+ homeostasis in cerebral ischemia. Cell Tissue Res 357:395-405. |journal=Cell Tissue Res
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  • ...Contextual tissue cytometry with artificial intelligence–functional single cell analyses ''in-situ''. '''Bioblast 2022: BEC Inaugural Conference.''' In: ht ...makes diagnostic routine applications not only possible but also feasible and that the market demand for such solutions has reached a level where it has
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  • ...normal colon tissue samples we examined tubulin βI, βII, βIII and βIV mRNA and protein expression profiles. Our results show that tubulin βII expression |tissues=Endothelial;epithelial;mesothelial cell
    3 KB (373 words) - 14:53, 10 June 2015
  • ...C, Berthet J (1954) The use of differential centrifugation in the study of tissue enzymes. Int Rev Cytol 3:225-75. ...many processes discovered by biochemists actually do take place within the cell.
    1 KB (222 words) - 15:14, 27 May 2015
  • ...berts LD (2021) Sexual dimorphism in adipose tissue mitochondrial function and metabolic flexibility in obesity. Int J Obes (Lond) 45:1773-81. ...d metabolism is poorly defined. We hypothesise that depot-specific adipose tissue mitochondrial function contributes to the sexual dimorphism of metabolic fl
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  • ...ernative oxidase]] pathway (Q-AOX), which is [[Antimycin_A| antimycin A]]- and [[cyanide| cyanide]] resistant. This protocol must be complemented with the == Strengths and limitations ==
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  • ...e]] pathway (CIII-CIV), which is inhibited by [[Antimycin_A| antimycin A]] and [[cyanide| cyanide]]. This protocol must be complemented with the study in == Strengths and limitations ==
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  • ...n rewires energy metabolism and induces browning features in adipose cells and tissues. Commun Biol 3:237. ...hite adipose tissue, which lies at the crossroads of nutrition, metabolism and immunity, may play in influenza infection.
    2 KB (300 words) - 11:47, 22 December 2020
  • ...1) Endogenous fatty acid synthesis drives brown adipose tissue involution. Cell Rep 34:108624. |journal=Cell Rep
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  • == Strengths and limitations == ...ount (''N''<sub>ce</sub>) is the sum of viable cells (''N''<sub>vce</sub>) and dead cells (''N''<sub>dce</sub>).
    4 KB (562 words) - 23:48, 12 April 2021
  • ...Liu Danhui, Lu J, Bai Y (2013) Comparative bioenergetic study of neuronal and muscle mitochondria during aging. Free Radic Biol Med 63:30-40. ...rious ages in muscle and brain. These findings indicate the existence of a tissue-specific regulatory mechanism for oxidative phosphorylation.
    2 KB (253 words) - 18:51, 29 February 2020
  • ...ceptor signaling ameliorates the effects of aging and counteracts obesity. Cell Metab 32:56-70.e7. |journal=Cell Metab
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  • ...T-018]]''' - SUIT protocol for simultaneous determination of O<sub>2</sub> and H<sub>2</sub>O<sub>2</sub> flux in permeabilized cells at various oxygen co ...he AmR assay can be tested in separate protocols: [[SUIT-003 AmR ce D058]] and [[SUIT-003 AmR ce D059]]. For further information, ''see'': [[Amplex UltraR
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  • ...al in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells) -'''[[SUIT-006]]''' ...bilized when they are added to the chamber) in a wide variety of organisms and tissues.
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  • ...Cunha-Neto E, Nunes JPS (2021) Mitochondria as a cellular hub in infection and inflammation. Int J Mol Sci 22:11338. https://doi.org/10.3390/ijms222111338 ...promising mitochondrial targets for the fight against infectious diseases and chronic inflammatory diseases.
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  • ...nt in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells) ...cated by [[Cardoso LH]], [[Komlodi T]], [[Huete-Ortega M]], [[Doerrier C]] and [[Gnaiger E]] (last update 2019-06-06)
    3 KB (368 words) - 23:53, 12 April 2021
  • ...ardiomyopathy: Mitochondria, oxidative stress and apoptosis. Int J Biochem Cell Biol 89:125-35. https://doi.org/10.1016/j.biocel.2017.06.009 |journal=Int J Biochem Cell Biol
    2 KB (291 words) - 05:40, 30 October 2023
  • |title=Ernster L, Schatz G (1981) Mitochondria: a historical review. J Cell Biol 91:227s-55s. |journal=J Cell Biol
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  • ...023) Boosting intracellular sodium selectively kills hepatocarcinoma cells and induces hepatocellular carcinoma tumor shrinkage in mice. https://doi.org/1 ...C cells are, unlike healthy cells, energetically incapable of compensating and surviving a pharmacologically induced Na<sup>+</sup> load, highlighting Na<
    2 KB (349 words) - 12:07, 6 June 2023
  • ...effects of R-phenibut after experimental traumatic brain injury. Oxid Med Cell Longev 2020:9364598. |journal=Oxid Med Cell Longev
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  • ...2010) Feedback between p21 and reactive oxygen production is necessary for cell senescence. Mol Syst Biol 6:347. ...foci and maintain an ongoing DDR. We show that this loop is both necessary and sufficient for the stability of growth arrest during the establishment of t
    2 KB (302 words) - 12:16, 19 March 2015
  • ...tabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence. JCI Insight 6:e154089. ...metabolism caused reversible mitochondrial dysfunction by transcriptional and translational perturbations in multiple pathways with a distinct skeletal m
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  • ...aneously O<sub>2</sub> flux and the Q-redox state in isolated mitochondria and permeabilized cells. ...ation of O<sub>2</sub> flux and the Q-redox state in isolated mitochondria and cells permeabilized previously to addition to the O2k-chamber.
    4 KB (623 words) - 17:57, 13 December 2023
  • ...oya S, Yuzuriha T, Katayama K (1984) Simultaneous determination of reduced and oxidized ubiquinones. Methods Enzymol 105:147-55. ...ollowed by quantitation by means of reversed-phase chromatography with UVD and ECD.
    2 KB (244 words) - 13:59, 24 August 2021
  • ...asis and lifespan by promoting mitoribosome integrity and translation. Nat Cell Biol 20:162-74. |journal=Nat Cell Biol
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  • Communicated by [[Cardoso LHD]], [[Doerrier C]] and [[Gnaiger E]] (last update 2019-03-06) == Strengths and limitations ==
    3 KB (424 words) - 14:38, 17 September 2020
  • ...2020) Mitochondrial respiration in KRAS and BRAF mutated colorectal tumors and polyps. Cancers (Basel) 12:E815. ...markers KRAS and BRAF are likely related to the metabolic phenotype in CRC and polyps. Assessment of the tumor mitochondrial ATP synthesis could be a pote
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  • ...ty| ''E'']]) with NADH-linked substrates ([[PM-pathway control state|PM]]) and the contribution of the [[S-pathway control state| S-pathway]] to the ET st == Strengths and limitations ==
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  • |info='''A: simultaneous determination of O2 flux and mt-membrane potential''' ...itochondria and tissue homogenate. The protocol can be applied to cells or tissue types that display a preference for either [[GM-pathway_control_state |GM]]
    5 KB (756 words) - 15:03, 17 September 2020
  • ...nib and sorafenib in isolated rat heart fibers and the cardiomyoblast H9c2 cell line. Int J Mol Sci 23:2282. https://doi.org/10.3390/ijms23042282 ...s of the ETS, which was associated with mitochondrial ROS accumulation and cell death by apoptosis.
    3 KB (381 words) - 11:24, 20 February 2022
  • ...le R, Bidaux G, Heliot L, Poulain L, Furlan A, Tulasne D (2020) Control of cell death/survival balance by the MET dependence receptor. Elife 9:e50041. ...hed light on new signaling mechanisms for dependence receptors' control of cell survival/death balance, which may offer new clues for the pathophysiology o
    2 KB (285 words) - 11:46, 22 December 2020
  • ...ruu.JPG|left|90px|Laura Truu]] Bioenergetic comparison of human colorectal and breast cancer clinical patients. ...ority of these conclusions are the outcome of only ''in vitro'' studies on cell culture models, without taking into consideration the factors arising from
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  • == Strengths and limitations == :::# Malate concentration that does not stimulate malate anaplerotic pathway, and therefore could be used to study [[F-pathway]] without [[N-pathway]] contri
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  • ...ecificity of substrates utilization in rat cardiac and skeletal muscles. J Cell Physiol 203:479-86. |journal=J Cell Physiol
    2 KB (356 words) - 17:54, 16 January 2021
  • ...hod for isolating functionally intact mitochondria from cultured cells and tissue biopsies. Anal Biochem 443:66-74. ...ally active, intact mitochondria from cultured or primary cells and minute tissue samples in a rapid, highly reproducible manner.
    2 KB (203 words) - 11:41, 15 March 2021
  • {{MitoPedia O2k and high-resolution respirometry}} ...physiologically relevant estimate of maximum [[OXPHOS capacity| OXPHOS-]] and [[ET capacity |ET capacity]]. SUIT-005 can be extended with the CIV assay m
    3 KB (424 words) - 14:30, 10 March 2023
  • ...V, Saks V (2013) Metabolic control analysis of respiration in human cancer tissue. Front Physiol 4:151. ...he data obtained show that MCA applied in situ can be insightful in cancer cell energetic research.
    2 KB (318 words) - 11:31, 28 April 2015
  • ...gy of hypoxia: the role of oxygen sensing in development, normal function, and disease. Genes Dev 18(18):2183-94. ...thways involved in oxygen sensing that are required for normal development and that are dysregulated in disease states. It will also comment on future dir
    1 KB (162 words) - 13:52, 31 May 2019
  • ...are more pronounced with small volumes of colloids in swine. Am J Physiol Cell Physiol 317:C1229-38. |journal=Am J Physiol Cell Physiol
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  • ...h the pool of redox intermediates in the pathway from CII to CIII and CIV, and if the capacity of the phosphorylation system does not limit OXPHOS capacit |info=[[Gnaiger 2020 BEC MitoPathways]], [[Gnaiger_2009_Int J Biochem Cell Biol]]
    3 KB (428 words) - 15:34, 31 January 2024
  • ...parations]] (isolated mitochondria, tissue homogenate, permeabilized cells and permeabilized fibers). [[Malate]] alone does not support respiration of mt- Communicated by [[Cardoso LHD]], [[Garcia-Souza LF]] and [[Doerrier Carolina|Doerrier C]] (last update 2020-04-30)
    3 KB (429 words) - 12:04, 3 June 2020
  • ...upling-control protocol to analyze mitochondrial O<sub>2</sub> consumption and the redox state of the Q-pool in S(Rot)-pathway control state in isolated m Communicated by [[Komlodi T]] and [[Cardoso LHD]] (last update 2023-12-18)
    3 KB (404 words) - 14:23, 18 December 2023
  • ...Gangjee A, Ihnat MA (2016) AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization. Cancer Lett pii: S0304-3835(16)30745 ...tor that increases oxidative metabolism, resulted in synergistic cell kill and reduced tumor growth. The inhibition of mitochondrial oxygen consumption by
    2 KB (310 words) - 09:30, 23 December 2016
  • ...er D (2016) Mitochondrial function controls intestinal epithelial stemness and proliferation. Nat Commun 7:13171. ...IEC to be pivotal in the control of the proliferative capacity of the stem cell niche.
    2 KB (288 words) - 11:26, 27 August 2018
  • ...n SE, Zhang N, Reddick RL, Musi N (2018) NFκB regulates muscle development and mitochondrial function. J Gerontol A Biol Sci Med Sci 75:647-53. ...hondrial function and muscle mass are tightly associated in both genotypes and across the lifespan.
    2 KB (320 words) - 15:32, 7 May 2020
  • ...ede epigenetic modifications of genes involved in muscle energy metabolism and the long-term improvement of insulin sensitivity. |area=Respiration, nDNA;cell genetics, mt-Medicine, Patients
    2 KB (272 words) - 15:50, 7 June 2022
  • ...ochondrial DNA in vascular smooth muscle cells impairs cell contractility. Cell Death Dis 11:35. |journal=Cell Death Dis
    2 KB (323 words) - 16:35, 29 February 2020
  • ...ration of mitochondrial biogenesis and respiratory capacity. Int J Biochem Cell Biol 41:2566-77. |journal=Int J Biochem Cell Biol
    3 KB (355 words) - 08:23, 21 February 2020
  • ...hat a high proton motive force in state 4 is potentially dangerous for the cell due to an increase in the probability of superoxide formation. {{Template:Cited by Komlodi 2021 MitoFit Tissue normoxia}}
    2 KB (240 words) - 20:18, 7 April 2022
  • ...Z, Wasserman DH, Rottman JN, Hittel DS, Shearer J (2013) Mesenchymal stem cell transplantation for the infarcted heart: therapeutic potential for insulin ...d systemic metabolism mediated by a combination of a myocardial infarction and diet-induced insulin resistance.
    3 KB (364 words) - 15:04, 28 March 2018
  • ...erson CA, Thayne K, Chitwood WR, Kypson AP (2011) Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathwa ...viable target for future therapies directed at ameliorating heart failure and other co-morbidities that come with diabetes.
    3 KB (448 words) - 16:40, 14 October 2019
  • primary prostate cancer tissue. (OXPHOS), supply starting products for cell components and are centrally involved in the execution of apoptosis. There is evidence tha
    3 KB (467 words) - 13:00, 23 March 2018
  • == Strengths and limitations == ...ntially interfering pathways, both in the [[LEAK respiration| LEAK state]] and in [[Oxidative phosphorylation| OXPHOS]].
    3 KB (397 words) - 11:37, 29 February 2024
  • ...n induces oxidative metabolism and mitigates obesity by regulating adipose tissue miRNA expression. Sci Adv 6:eabc6250. ...thermogenic signaling and inducing oxidative metabolism in adipose tissue and skeletal muscle in a mechanism that involves, at least in part, miRNA-media
    3 KB (361 words) - 22:47, 11 December 2020
  • ...cle myobundles to measure oxygen uptake and assess mitochondrial toxicity. Tissue Eng Part C Methods 23:189-99. |journal=Tissue Eng Part C Methods
    3 KB (338 words) - 13:22, 4 June 2018
  • ...ic GpDH. CGpDH oxidizes [[glycerophosphate]] to dihydroxyacetone phosphate and feeds two electrons into the [[Q-junction]], thus linked to an [[Electron-t |?Mammal and model
    962 bytes (116 words) - 15:09, 3 September 2023
  • ...ce in mitochondrial preparations (isolated mitochondria, tissue homogenate and permeabilized cells)- '''[[SUIT-032]]''' == Strengths and limitations ==
    3 KB (442 words) - 10:37, 12 January 2024
  • ...metabolic properties of renal epithelial cell cultures. Are renal cells in tissue culture hypoxic? https://doi.org/10.1159/000016312 ...f-renal-epithelial-cell-cultures-Are-renal-cells-in-tissue-culture-hypoxic-Cell-Physiol-Biochem.pdf Open Access]
    6 KB (876 words) - 19:00, 5 June 2022
  • ...l with NADH-linked substrates for isolated mitochondria, tissue homogenate and permeabilized cells- '''[[SUIT-012]]''' == Strengths and limitations ==
    3 KB (397 words) - 00:12, 13 April 2021
  • Communicated by [[Cardoso LHD]] and [[Gnaiger E]] (last update 2019-02-14) == Strengths and limitations ==
    3 KB (496 words) - 12:08, 17 September 2020
  • ...proteins that can be found in the inner mitochondrial membranes of animals and plants. [[Uncoupling protein 1 |UCP1]] acts as an [[uncoupler]] by dissipat ...n elicited by cold exposure, including ROS and lipid metabolism, apoptosis and thermogenesis.<ref>Criscuolo F, Gonzalez‐Barroso MdM, Bouillaud F, Ricqui
    4 KB (559 words) - 14:23, 8 June 2020
  • == Strengths and limitations == :::+ Pathway control in OXPHOS (F, F(N), FN, FNS and S pathways) can be evaluated.
    2 KB (345 words) - 10:29, 18 September 2020
  • |title=Ost M (2015) “Mitokines” and the organismal role of mitochondrial function in energy homeostasis & metab ...l autonomous roles, showing that an impaired mitochondrial function in one tissue (e.g. skeletal muscle) has strong metabolic consequences for the whole orga
    2 KB (332 words) - 12:55, 21 February 2023
  • ...ation of renal cysts and tumors in Vhl/Trp53-deficient mice requires HIF1α and HIF2α. Cancer Res 76:2025-36. ...nd HIF2α exert protumorigenic functions during the earliest stages of cyst and tumor formation in the kidney.
    2 KB (358 words) - 12:03, 28 March 2018
  • |title=Fernandez-Vizarra E (2013) Testing OXPHOS biogenesis and function in mitochondrial disease models. Mitochondr Physiol Network 18.09. ...continue with the analyses of physical status of OXPHOS-related complexes and their individual activities.
    2 KB (300 words) - 10:40, 9 November 2016
  • ...upplementation on energy metabolism and metabolic profile in obese humans. Cell Metab 14:612-22. |journal=Cell Metab
    2 KB (312 words) - 09:13, 27 January 2020
  • ...M, Sidossis LS (2015) Morphological changes in subcutaneous white adipose tissue after severe burn injury. J Burn Care Res 37:e96-e103. ...sociated with tissue inflammation. A better understanding of morphological and functional changes in sWAT will help discern the mechanisms underlying hype
    3 KB (374 words) - 10:03, 8 November 2016
  • ...heede-Bergdahl C, Bergdahl A (2017) Adaptation of mitochondrial expression and ATP production in dedifferentiating vascular smooth muscle cells. Can J Phy ...erosclerotic process and that detectable changes in mitochondrial function and expression are related to VSMC dedifferentiation.
    3 KB (344 words) - 10:10, 12 December 2017
  • ...CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47. ...a significant contributor to the overall increase in metabolic flexibility and uncoupled respiration produced by the diet.
    2 KB (309 words) - 15:35, 13 November 2017
  • ...Brandt T, Mourier A, Stewart JB, Larsson NG, Kühlbrandt W (2013) Structure and function of aged mouse mitochondria. Mitochondr Physiol Network 18.08. |abstract=Mitochondria are the energy-converting cell organelles. Their dysfunction has been described as a cause or symptom of a
    3 KB (432 words) - 11:04, 28 April 2017

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