Search results

• Ohashi 2012 Nat Commun
  ...K (2012) Identification and characterization of a human mitochondrial NAD kinase . Nat Commun 3:1248. ...uman HEK293A cells. C5orf33 mRNA is more abundant than human cytosolic NAD kinase mRNA in almost all tissues examined. We further show by database searches t
  1 KB (202 words) - 17:13, 21 February 2022
• Bartrons 2004 Cryobiology
  ...N, Navarro-Sabaté A, Bartrons R (2004) Activation of AMP-dependent protein kinase by hypoxia and hypothermia in the liver of frog Rana perezi. Cryobiology 49 |authors=Bartrons M, Ortega E, Obach M, Calvo MN, Navarro-Sabate A, Bartrons R
  2 KB (230 words) - 09:28, 9 November 2016
• AMPK
  |description='''AMP-activated protein kinase''' is a regulatory protein which acts as crucial cellular energy sensor by sensing AMP, [[ADP]] and/or ...nserving ATP by downregulating anabolic pathways. AMPK is a heterotrimeric protein (catalytic α-subunit and regulatory β- and γ-subunits). The well-known o
  2 KB (289 words) - 08:58, 21 May 2012
• Kang 2017 Mol Cell
  ...sociated mitochondrial acylglycerol kinase is a subunit of the human TIM22 protein import complex. Mol Cell 67:457-70. ...it of TIM22 provides an exciting and unexpected link between mitochondrial protein import and Sengers syndrome.
  2 KB (288 words) - 22:38, 1 December 2018
• O´Gorman 1997 FEBS Lett
  ...Dolder M, Koretsky AP, Brdiczka D, Wallimann T (1997) The role of creatine kinase in inhibition of mitochondrial permeability transition. FEBS Lett 414:253-7 ...e. No malate release occurred with complexes containing octameric creatine kinase under the same conditions.
  2 KB (220 words) - 15:37, 15 June 2015
• Chowdhury 2012 Brain
  ...NA, Fernyhough P (2012) Impaired adenosine monophosphate-activated protein kinase signalling in dorsal root ganglia neurons is linked to mitochondrial dysfun |authors=Chowdhury SK, Smith DR, Saleh A, Schapansky J, Marquez A, Gomes S, Akude E, Morrow D, Calcutt NA, Fernyhough P
  3 KB (422 words) - 08:23, 21 February 2020
• Nin 2012 J Biol Chem
  ...acetylase activation induced by protein kinase A and AMP-activated protein kinase. J Biol Chem 287:23489-501. ...s provide new insight on the ''in vivo'' mechanism of SIRT1 regulation and a new avenue for the development of pharmacological SIRT1 activators targeted
  2 KB (363 words) - 12:17, 8 November 2016
• Roth 2010 Aging (Albany NY)
  |title=Flach RJ, Bennett AM (2010) MAP kinase phosphatase-1 - a new player at the nexus between sarcopenia and metabolic disease. Aging (Al ...sarcopenia and overnutrition in a pathophysiological pathway that leads to a loss of skeletal muscle mitochondrial function. With the increasing aging p
  2 KB (268 words) - 12:45, 19 March 2015
• Djeungoue-Petga 2019 Cell Death Dis
  ...Bou M, Cannich A, Roy P, Hebert-Chatelain E (2019) Intramitochondrial Src kinase links mitochondrial dysfunctions and aggressiveness of breast cancer cells. ...etga MA, Lurette O, Jean S, Hamel-Cote G, Martín-Jimenez R, Bou M, Cannich A, Roy P, Hebert-Chatelain E
  2 KB (334 words) - 10:36, 27 January 2020
• Hardeland 2009 Biofactors
  |title=Hardeland R (2009) Melatonin: signaling mechanisms of a pleiotropic agent. Biofactors 35:183-92. ...ma membrane, such as an orphan GPCR, GPR50, and the PDZ domain scaffolding protein MUPP1, effects which negatively or positively influence signaling capacity.
  2 KB (320 words) - 08:06, 21 February 2020
• Kowluru 2010 Diabetes
  |title=Kowluru A, Veluthakal R, Rhodes CJ, Kamath V, Syed I, Koch BJ. (2010) Protein farnesylation-dependent raf/erk signaling links to cytoskeletal remodeling |authors=Kowluru A, Veluthakal R, Rhodes CJ, Kamath V, Syed I, Koch BJ
  2 KB (321 words) - 08:22, 31 March 2017
• Xiong 2016 Hypertension
  ...nsient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60. ...mitochondrial dysfunction. Dietary capsaicin supplementation may represent a promising intervention for the primary prevention of coronary heart disease
  3 KB (432 words) - 19:28, 29 February 2020
• Qvit 2022 Pharmaceuticals (Basel)
  ...of cardiac troponin I phosphorylation by delta protein kinase C (δPKC) as a treatment for ischemia-reperfusion injury. https://doi.org/10.3390/ph150302 ...injury, and that a cTnI/δPKC interaction inhibitor should be considered as a therapeutic target to reduce cardiac injury after myocardial infarction.
  2 KB (280 words) - 18:55, 6 December 2022
• Garcia-Roves 2008 J Biol Chem
  ...Zierath JR (2008) Gain-of-function R225Q mutation in AMP-activated protein kinase gamma3 subunit increases mitochondrial biogenesis in glycolytic skeletal mu ...up> mice, independent of changes in fiber type composition. In conclusion, a single nucleotide mutation (R225Q) in the AMPK gamma3 subunit is associated
  3 KB (346 words) - 09:46, 15 December 2014
• Pape 2018 Nutrients
  ...ration on a standard diet and decreases liver triglyceride accumulation on a western high-fat high-sugar diet. Nutrients 10:1990. |authors=Pape JA, Newey CR, Burrell HR, Workman A, Perry K, Bikman BT, Bridgewater LC, Grose JH
  3 KB (372 words) - 10:02, 29 July 2019
• Dejean 2002 Biochem Biophys Res Comm
  ...DNA genes was unchanged. It is concluded that the Ras/cAMP/protein kinase A pathway is part of the regulatory circuit controlling biogenesis of the oxi |mipnetlab=FR Pessac Diolez P, FR Bordeaux Devin A
  2 KB (243 words) - 12:43, 16 February 2018
• Kristensen 2013 PLoS One
  ...in treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice. PLoS One 8:e53533. ...he respiration defect compared to the WT mice. Metformin did not influence protein activities or expressions in either WT or AMPK KD mice.
  3 KB (396 words) - 04:10, 12 February 2020
• Costa 2013 Cell Death Dis
  ...(2013) ''Drosophila'' Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease. Cell Death Dis 4:e467. ...rap1 function with Pink1 and parkin. We show that loss of Trap1 results in a decrease in mitochondrial function and increased sensitivity to stress, and
  3 KB (340 words) - 12:14, 27 March 2018
• Stefan 2022 Abstract Bioblast
  ...> (2022) Tracking patient-mutation and lead-molecule driven alterations of kinase activity conformations. '''Bioblast 2022: BEC Inaugural Conference.''' In: ...icine-oriented KinCon biosensor concept is not restricted to recordings of kinase drug efficacies/specificities. We have first evidence that such conformatio
  3 KB (438 words) - 08:44, 28 July 2022
• Poudel 2019 Can J Physiol Pharmacol
  |title=Poudel A, Zhou JY, Mekala N, Welchko R, Rosca MG, Li L (2019) Berberine hydrochlorid |authors=Poudel A, Zhou JY, Mekala N, Welchko R, Rosca MG, Li L
  2 KB (330 words) - 16:17, 11 February 2020
• MacPherson 2016 Am J Physiol Cell Physiol
  ...) inhibitor ATGListatin attenuated the Thr(172) phosphorylation of AMPK by a β3-adrenergic agonist (CL 316,243) independent of changes in PKA signaling |keywords=5′-AMP-activated protein kinase, Adipose tissue triglyceride lipase, Lipolysis, Mitochondria, Mouse, White
  2 KB (334 words) - 14:45, 31 July 2017
• Mungai 2011 Mol Cell Biol
  |title=Mungai PT, Waypa GB, Jairaman A, Prakriya M, Dokic D, Ball MK, Schumacker PT (2011) Hypoxia Triggers AMPK A |authors=Mungai PT, Waypa GB, Jairaman A, Prakriya M, Dokic D, Ball MK, Schumacker PT
  2 KB (287 words) - 15:39, 11 February 2022
• Kamath 2010
  ...of glucose-and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic β-cells.. Am J Physiol Endocrinol Meta ...N, Jayaram B, Syed I, Olson LK, Ludwig K, Klumpp S, Krieglstein J, Kowluru A.
  2 KB (317 words) - 10:51, 21 November 2012
• Liem 2008 Transl Res
  |title=Liem D, Manintveld O, Schoonderwoerd K, McFalls E, Heinen A, Verdouw P, Sluiter W, Duncker D (2008) Ischemic preconditioning modulates |authors=Liem D, Manintveld O, Schoonderwoerd K, McFalls E, Heinen A, Verdouw P, Sluiter W, Duncker D
  3 KB (363 words) - 15:10, 13 November 2017
• Lark 2015 Front Physiol
  ...LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD (2015) Protein kinase A governs oxidative phosphorylation kinetics and oxidant emitting potential a ...nderstanding of how mitochondrial cAMP production is regulated, illustrate a need for better tools to examine the impact of sAC activity on mitochondria
  3 KB (362 words) - 15:38, 4 January 2023
• Stride 2012 Front Physiol
  ...jtaszewski JF, Richter EA, Køber L, Dela F (2012) 5'-AMP activated protein kinase is involved in the regulation of myocardial β-oxidative capacity in mice. ...and that decreased AMPK activity may lead to an altered energetic state as a consequence of reduced capacity to oxidize MCFA. We did not identify any cl
  3 KB (371 words) - 15:45, 5 March 2019
• Pimenta 2012 Cell Death Differ
  ...ale D, Deas E, Loh SH, Martins LM (2012) Genetic analysis of mitochondrial protein misfolding in ''Drosophila melanogaster''. Cell Death Differ doi:10.1038/cd ...thway involving pink1, parkin and ref(2)P has a role in the maintenance of a viable pool of cellular mitochondria by promoting organellar quality contro
  2 KB (312 words) - 13:37, 27 March 2018
• Strich 2023 MiPschool Obergurgl
  ...0px|Mitochondrial Physiology Society|MiPsociety]]Bioenergetic profiling of kinase inhibitors reveals drug off-targer effects in colon cancer cell models ...gle or multiple oncogenic kinase pathways [2]. In these lines, blockade of kinase activities has been shown to converge on the central energetic organelle, t
  4 KB (554 words) - 16:07, 28 June 2023
• Trefts 2019 Thesis
  |title=Trefts E (2019) Integrin linked kinase is critical for hepatic cellular organization, metabolism, and glucoregulat ...s protein during obesity and the spectrum of benefits that occur when this protein is removed from hepatocytes. This work also establishes the underlying mech
  2 KB (325 words) - 14:03, 24 April 2019
• Barbieri 2016 Abstract Mito Xmas Meeting Innsbruck
  ...starvation, FIS1 variant 2 expression is up-regulated in a protein kinase A-dependent manner and its specific knockdown inhibits autophagy associated m
  1 KB (186 words) - 12:51, 7 December 2016
• Kamath 2010 Am J Physiol Endocrinol Metab
  ...f glucose- and mitochondrial fuel-induced insulin secretion by a cytosolic protein histidine phosphatase in pancreatic beta-cells. Am J Physiol Endocrinol Met ...N, Jayaram B, Syed I, Olson LK, Ludwig K, Klumpp S, Krieglstein J, Kowluru A.
  2 KB (341 words) - 15:08, 26 May 2015
• Scarpelli 2018 J Pineal Res
  ...um falciparum'' related-genes for mitochondria fission: mitoemerald-GFP as a tool to visualize mitochondria structure. J Pineal Res 66:e12484. ...meida GT, Vicoso KL, Lima WR, Pereira LB, Meissner KA, Wrenger C, Rafaello A, Rizzuto R, Pozzan T, Garcia CRS
  3 KB (406 words) - 00:55, 10 February 2020
• Bhargava 2017 Nat Rev Nephrol
  ...betes mellitus. Furthermore, inhibiting the fission protein dynamin 1-like protein (DRP1) might ameliorate ischaemic renal injury by blocking mitochondrial fi
  2 KB (239 words) - 12:49, 22 October 2023
• Docherty 2018 Atherosclerosis
  ...mpaired mitochondrial respiration in human carotid plaque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics. Atheros |authors=Docherty CK, Carswell A, Friel E, Mercer JR
  3 KB (362 words) - 15:33, 29 January 2018
• Bassot 2023 Cell Rep
  ...Zito E, Bogeski I, Campbell RE, Simmen T (2023) The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochon ...les, while limiting oxidative stress. Therefore, the PERK-ERO1⍺ complex is a key molecular machinery that allows quick metabolic adaptation to ER stress
  2 KB (335 words) - 15:09, 13 March 2024
• Hlavata 2008 Aging Cell
  ...Hlavatá L, Nachin L, Jezek P, Nyström T (2008) Elevated Ras/protein kinase A activity in ''Saccharomyces cerevisiae'' reduces proliferation rate and lif ...art, to elevated levels of reactive oxygen species (ROS), which also cause a proteolysis-dependent fragmentation of the Aac2p carrier both ''in vivo''
  2 KB (298 words) - 09:22, 9 November 2016
• Eira da Costa 2013 Abstract MiP2013
  ...(2013) ''Drosophila Trap1'' protects against mitochondrial dysfunction in a ''PINK1/parkin'' model of Parkinson’s disease. Mitochondr Physiol Network ...1 function with Pink1 and parkin. We showed that loss of Trap1 resulted in a decrease in mitochondrial function and increased sensitivity to stress, and
  2 KB (319 words) - 11:11, 28 April 2017
• Tilokani 2022 Sci Adv
  ...tion. Together, these findings identify MTFR1L as a critical mitochondrial protein transducing AMPK-dependent metabolic changes through regulation of mitochon
  2 KB (287 words) - 19:29, 15 November 2022
• Di 2011 EMBO J
  ...11) H₂O₂ stress-specific regulation of S. pombe MAPK Sty1 by mitochondrial protein phosphatase Ptc4. EMBO J 31:563-75. |authors=Di Y, Holmes EJ, Butt A, Dawson K, Mironov A, Kotiadis VN, Gourlay CW, Jones N, Wilkinson CR
  2 KB (274 words) - 16:28, 23 February 2015
• De Jager 2017 Adv Exp Med Biol
  ...ic oxide synthase (NOS) synthesis. It may also cause a decrease in protein kinase C (PKC) expression leading to increased ROS production. UVR is capable of m |keywords=antioxidants, catalase, nitric oxide, oxidant, protein kinase C, reactive oxygen species
  2 KB (278 words) - 09:53, 3 May 2022
• Strub 2011 FASEB J
  ...efsky EJ, Spiegel S (2011) Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate Complex IV assemb ...mitochondrial respiration through cytochrome-c oxidase. Our data point to a new action of S1P in mitochondria and suggest that interaction of S1P with
  2 KB (305 words) - 12:56, 25 February 2020
• Valek 2016 Redox Biol
  ...(2016) Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain. Redox Biol 11:176-91. |authors=Valek L, Haeussler A, Droese S, Eaton P, Schroeder K, Tegeder I
  2 KB (339 words) - 09:43, 16 November 2017
• Chen 2020 Biochim Biophys Acta Mol Basis Dis
  ...CM, Bikman BT, Hansen JM, Thomson DM (2020) Lack of skeletal muscle liver kinase B1 alters gene expression, mitochondrial content, inflammation and oxidativ ...eletal muscle does not exacerbate obesity or insulin resistance in mice on a HFD, despite impaired mitochondrial content and function and elevated infla
  3 KB (396 words) - 17:54, 1 July 2020
• Jian 2020 Cell Metab
  ..., Huang Z, She ZG, Zhang XJ, Zhu L, Li H (2020) Low-dose sorafenib acts as a mitochondrial uncoupler and ameliorates nonalcoholic steatohepatitis. Cell ...this new therapeutic strategy for NASH has the potential to translate into a beneficial anti-NASH therapy with fewer adverse events than is observed in
  3 KB (398 words) - 19:31, 25 April 2023
• O´Gorman 1996 Biochim Biophys Acta
  ...compared to control. In GPA-fed rats, the specific activities of adenylate kinase (ADK) and succinate dehydrogenase were significantly higher in brain and so ...Guanidino propionic acid; Creatine; Mitochondrial inclusion body; Creatine kinase; Adenine nucleotide translocator; Metabolism; Oxidative phosphorylation; (R
  3 KB (364 words) - 14:08, 27 March 2015
• Stouth 2023 Autophagy
  ...out Tiffany L, Mikhail Andrew I, Ng Sean Y, Raziee Rozhin, Edgett Brittany A, Vasam Goutham, Webb Erin K, Gilotra Kevin S, Markou Matthew, Pineda Hannah ...1 deletion also elicited PPARGC1A (PPARG coactivator 1 alpha) activity and a slower, more oxidative muscle phenotype. As such, these carm1 mKO-evoked ad
  3 KB (414 words) - 17:30, 6 December 2023
• Gupte 2009 Diabetes
  ...cose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet. Diabetes 58:567-78. |abstract=OBJECTIVE—Heat treatment and overexpression of heat shock protein 72 (HSP72) have been shown to protect against high-fat diet–induced insul
  3 KB (367 words) - 10:58, 3 December 2019
• Chambers 2021 JCI Insight
  ...per MA, Swearingen AR, Brookheart RT, Schweitzer GG, Weinheimer CJ, Kovacs A, Koves TR, Muoio DM, McCommis KS, Finck BN (2021) Myocardial Lipin 1 knocko |authors=Chambers Kari T, Cooper Michael A, Swearingen Alison R, Brookheart Rita T, Schweitzer George G, Weinheimer Ca
  3 KB (371 words) - 13:09, 11 August 2021
• Fang 2010 Cell
  ...ang S, Zhao L, Chen S, Mak TW, Wang X (2010) The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. ...ENTPD5 is therefore an integral part of the PI3K/PTEN regulatory loop and a potential target for anticancer therapy
  2 KB (304 words) - 04:58, 21 November 2023
• Sundaram 2015 Mol Microbiol
  ...ctivation and Bcy1 phosphorylation converging in PKA inhibition. Slt2/Mpk1 kinase partially contributes to Bcy1 phosphorylation, although additional targets
  2 KB (270 words) - 17:18, 23 February 2020
• Elksnis 2021 Clin Sci (Lond)
  ...le=Elksnis A, Schiffer TA, Palm F, Wang Y, Cen J, Turpaev K, Ngamjariyawat A, Younis S, Huang S, Shen Y, Leng Y, Bergsten P, Karlsborn T, Welsh N, Wang |authors=Elksnis Andris, Schiffer Tomas A, Palm Fredrik, Wang Yun, Cen Jing, Turpaev Kyril, Ngamjariyawat Anongnad, Y
  2 KB (324 words) - 16:18, 2 December 2021
• Villani 2016 Mol Metab
  ...l-CoA carboxylase, and the p70S6 kinase were assessed. Overexpression of a protein that maintains complex-I supported mitochondrial respiration (NDI1) was use ...ed protein kinase AMPK, AMPK, 5′-adenosine monophosphate-activated protein kinase, Breast cancer, Cancer metabolism, Colon cancer, ECAR, Extracellular acidif
  3 KB (437 words) - 04:17, 12 February 2020
• Pirkmajer 2011 Am J Physiol Cell Physiol
  ...activity. Serum starvation clearly represents a major event that triggers a plethora of divergent responses and has therefore great potential to interf
  2 KB (282 words) - 15:55, 9 November 2016
• Gispert 2009 PLoS One
  ..., Fernández-Ruiz J, Huber L, Rohrer H, Barrera M, Reichert AS, Rüb U, Chen A, Nussbaum RL, Auburger G (2009) Parkinson phenotype in aged PINK1-deficient ...Fernandez-Ruiz J, Huber L, Rohrer H, Barrera M, Reichert AS, Rueb U, Chen A, Nussbaum RL, Auburger G
  3 KB (418 words) - 13:50, 7 May 2019
• Cannavino 2015 J Physiol
  ...C-1α completely preserves muscle mass by preventing the fall in pro-fusion protein expression, AMPK and catabolic system activation, suggesting that compounds ...boxylase (ACC) phosphorylation was found, suggesting AMP-activated protein kinase (AMPK) pathway activation. To test the role of mitochondrial alterations we
  4 KB (531 words) - 15:44, 7 November 2016
• Phang 2019 Antioxid Redox Signal
  ...lopment. Although first focused on proline catabolism, recent studies from a number of laboratories have emphasized the regulatory effects of proline sy ...ynthetic side, two well-recognized oncogenes, c-MYC and phosphoinositide 3-kinase (PI3K), markedly upregulate enzymes of proline synthesis; mechanisms affect
  2 KB (295 words) - 13:28, 19 February 2019
• Song 2020 Obes Facts
  ...ltitude-associated ambient hypoxia affects insulin sensitivity in mice fed a high-fat diet (HFD). Mice were randomly divided into a control group (with normal diet feeding and low-altitude housing), LA/HFD g
  3 KB (376 words) - 18:15, 6 November 2020
• Russell 2020 Nutrients
  |authors=Russell Jake S, Griffith Tia A, Naghipour Saba, Vider Jelena , Du Toit Eugene F, Patel Hemal H, Peart Jaso ...ction in T2D mice, unrelated to caveolins/cavins, mitochondrial, or stress kinase modulation. Although evidence suggests inflammatory involvement, the basis
  3 KB (331 words) - 19:47, 18 September 2020
• Jia 2018 Circ Res
  ...se C, microRNA, and exosome pathways. The aim of this review is to provide a contemporary view of these instigators of diabetic cardiomyopathy, as well
  3 KB (330 words) - 16:09, 24 February 2020
• Nijholt 2023 Sci Rep
  ...stenbrink BD (2023) A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exerc ...ina C, Wolters Anouk HG, Giepmans Ben NG, Sillje Herman HW, de Boer Rudolf A, Bakker Barbara M, Westenbrink B Daan
  3 KB (404 words) - 16:55, 7 November 2023
• Miranda 2013 Thesis Instituto de Biologia - Rio de Janeiro
  ...ção da grelina no coração de camundongos obesos após hipernutrição durante a lactação / Ghrelin signaling in the heart of obese mice after overnutriti ...KT and pAKT), phosphatidil inositol 3 kinase (PI3K), AMP-activated protein kinase (AMPK and pAMPK), mTOR and pmTOR, BAX, Bcl2 and actin was achieved by weste
  3 KB (381 words) - 13:13, 16 January 2014
• Esteves 2019 Oncogene
  |title=Esteves P, Dard L, Brillac A, Hubert C, Sarlak S, Rousseau B, Dumon E, Izotte J, Bonneu M, Lacombe D, Du |authors=Esteves P, Dard L, Brillac A, Hubert C, Sarlak S, Rousseau B, Dumon E, Izotte J, Bonneu M, Lacombe D, Du
  3 KB (363 words) - 11:27, 3 March 2020
• Pasdois 2007 Am J Physiol Heart Circ Physiol
  ...s rat hearts against ischemia-reperfusion injury via pathway involving src kinase, mitoKATP, and ROS. Am J Physiol Heart Circ Physiol 292:H1470-8. |authors=Pasdois P, Quinlan CL, Rissa A, Tariosse L, Vinassa B, Costa AD, Pierre SV, Dos Santos P, Garlid KD
  3 KB (436 words) - 12:42, 16 February 2018
• Serafini 2016 Abstract Mito Xmas Meeting Innsbruck
  ...ease gene LRRK2 as endoplasmic reticulum-mitochondria tether identified by a genome wide high content screen. |authors=Serafini A, Lakshminarayanan S, Giacomello, M, Scorrano L
  2 KB (334 words) - 17:32, 14 December 2016
• Makhnyeva 2015 Abstract MiPschool Greenville 2015
  |title=Effect of cGMP-dependent protein kinase (PKG) signaling on mitochondrial content in ''Drosophila melanogaster'' sub ...activity, whereas fruit flies with the Sitter allele of for (fors) express a low-enzymatic activity PKG; it was also demonstrated that upon return to no
  3 KB (451 words) - 09:14, 21 July 2015
• Hirsch 2012 PloS One
  ...er G, Mullis PE, Nuoffer JM, Flück CE (2012) Role of AMP-activated protein kinase on steroid hormone biosynthesis in adrenal NCI-H295R cells. PLoS One 7:e309 |authors=Hirsch A, Hahn D, Kempna P, Hofer G, Mullis PE, Nuoffer JM, Flueck CE
  3 KB (385 words) - 14:36, 13 November 2017
• Rosca 2011 Biochim Biophys Acta
  ...ibers, pre-incubation with cAMP decreases oxidative phosphorylation due to a defect localized at Complex IV of the ETC inter alia. We propose that phosp |keywords=Mitochondria, Supercomplex, Oxidative phosphorylation, Cardiolipin, Protein threonine phosphorylation
  2 KB (303 words) - 09:12, 16 June 2015
• Cigliano 2017 Mol Neurobiol
  ...=Cigliano L, Spagnuolo MS, Crescenzo R, Cancelliere R, Iannotta L, Mazzoli A, Liverini G, Iossa S (2017) Short-term fructose feeding induces inflammatio ...=Cigliano L, Spagnuolo MS, Crescenzo R, Cancelliere R, Iannotta L, Mazzoli A, Liverini G, Iossa S
  3 KB (376 words) - 12:08, 26 June 2019
• Gellerich 2002 Biochim Biophys Acta (Vol 1554)
  ...macromolecules on mitochondria. Under these conditions, mitochondria have a more native, condensed configuration. ...23 μM ADP (for a diffusion rate of JDif=1.9 μmol ADP/min/mg mitochondrial protein) were observed. These gradients are about twice those estimated in the abse
  3 KB (388 words) - 10:54, 23 January 2019
• Goo 2012 PLoS One
  ...-regulating mitochondrial respiratory capacity through the 4E-BP1-mediated protein translation pathway.
  3 KB (426 words) - 14:24, 13 November 2017
• De Lucas 2014 J Sports Sci
  ...k Silveira PC, Remor AP, da Luz Scheffer D, Antonacci Guglielmo LG, Latini A (2014) Increased platelet oxidative metabolism, blood oxidative stress and ...k Silveira PC, Remor AP, da Luz Scheffer D, Antonacci Guglielmo LG, Latini A
  3 KB (347 words) - 23:21, 29 February 2020
• Jelenik 2014 Diabetes
  ...4) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67. ...reased myocellular protein kinase C theta (PKCθ) activity and serum fetuin A levels. Muscle mitochondrial oxidative capacity is unchanged at the onset,
  2 KB (283 words) - 14:46, 13 November 2017
• Huisamen 2015 Abstract MiPschool Cape Town 2015
  |title=The ATM protein and myocardial mitochondria. 50% of the volume of a cardiomyocyte. A close link therefore exists
  6 KB (802 words) - 10:35, 23 March 2015
• Gross 2023 MiP2023
  |title=[[File:Atan Gross.png|left|100px|Gross Atan]] M(a)TCH2-ing up metabolism and apoptosis at the MOMbrane. ...l metabolism in skeletal muscle, protecting from diet-induced obesity, and a role in regulating mitochondrial fusion/elongation, which is important in d
  2 KB (285 words) - 16:43, 12 July 2023
• Cruz-Gregorio 2019 Biomolecules
  ...ins from high-risk human papillomavirus induce mitochondrial metabolism in a head and neck squamous cell carcinoma model. Biomolecules 9:E351. |authors=Cruz-Gregorio A, Aranda-Rivera AK, Aparicio-Trejo OE, Coronado-Martinez I, Pedraza-Chaverri
  2 KB (317 words) - 16:00, 23 October 2019
• Lamberti 2011 Plant Physiol
  ...f photosynthetic capacity during the first 6 h of deetiolation, supporting a role of cytosolic STY kinases in chloroplast differentiation.
  2 KB (211 words) - 10:16, 9 November 2016
• Petroutsos 2016 Nature
  ...L, Cusant L, Kottke T, Mittag M, Hegemann P, Finazzi G, Minagawa J (2016) A blue-light photoreceptor mediates the feedback regulation of photosynthesis ...g, utilization, and dissipation of light is a concerted process that plays a vital role in microalgal acclimation to environments of variable light inte
  2 KB (295 words) - 14:36, 21 March 2023
• Smith 2013 Biochem J
  |title=Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT (2 |authors=Smith ME, Tippetts TS, Brassfield ES, Tucker BJ, Ockey A, Swensen AC, Anthonymuthu TS, Washburn TD, Kane DA, Prince JT, Bikman BT
  2 KB (332 words) - 16:44, 27 March 2018
• De-Souza 2020 J Biol Chem
  ...rial respiration and lithium-galactose-mediated activation of the unfolded protein response. J Biol Chem 295:3773-82. ..., De-Queiroz ALFV, Camara H, Felix-Formiga ML, Machado CM, Pinto S, Galina A, Mori MA, Montero-Lomelí M, Masuda CA
  3 KB (390 words) - 15:36, 7 May 2020
• Dymkowska 2020 J Appl Toxicol
  |title=Dymkowska D, Wrzosek A, Zabłocki K (2020) Atorvastatin and pravastatin stimulate nitric oxide and ...or statins related to reduced histone H3 methylation due to increased NNMT protein level. Thus, NNMT may directly modify gene activity.
  2 KB (322 words) - 13:36, 20 October 2021
• Matsumoto 2021 Circ Heart Fail
  ...oxidation via the activation of adenosine monophosphate-activated protein kinase-ɑ - proliferator-activated receptor-r coactivator-1ɑ signaling in skeleta ...etal muscle via the AMPKα-PGC1α (adenosine monophosphate-activated protein kinase-ɑ-proliferator-activated receptor-r coactivator-1ɑ) axis.
  3 KB (402 words) - 08:55, 28 May 2021
• Den Besten 2015 Diabetes
  ...Short-chain fatty acids protect against high-fat diet-induced obesity via a PPARγ-dependent switch from lipogenesis to fat oxidation. Diabetes 64:2398 |authors=den Besten G, Bleeker A, Gerding A, van Eunen K, Havinga R, van Dijk TH, Oosterveer MH, Jonker JW, Groen AK, R
  2 KB (279 words) - 11:04, 8 November 2016
• Monge 2009 Can J Physiol Pharmacol 87:318-326.
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• Aoun 2015 Abstract MiP2015
  |authors=Aoun M, Acin-Perez R, Montorfano G, Rizzo A, Enriquez JA, Tiranti V ...an autosomal recessive inborn error of CoA metabolism, called pantothenate kinase-associated neurodegeneration (PKAN). The pathogenesis of PKAN, the most fre
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• Pernas MiP2010
  ...OP2 and ROP8 expression retain the ability to recruit host mitochondria in a manner that is indistinguishable from the parental strain re-opening two im ...ere labelled for 30 min at 37 oC with 50 nM MitoTracker and infected with (A) RH wild type; (B) Neospora caninum (NC-1); (C) RHΔrop2/8, or co-infected
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• Gdynia 2016 Nat Commun
  ...ster M, Zentgraf H, Schirmacher P, Roth W (2016) The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration. Nat Co ..., Mairbaeurl H, Kaminski MM, Penzel R, Zhang C, Fuller JC, Wade RC, Benner A, Chang-Claude J, Brenner H, Hoffmeister M, Zentgraf H, Schirmacher P, Roth
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• Liu 2019 J Ethnopharmacol
  ...drial dysfunction and neurodegeneration by inducing mitochondrial unfolded protein response in Drosophila melanogaster PINK1 model of Parkinson's disease. J E ...up> mutant Dm, we aimed to explore the therapeutic action of ginseng total protein (GTP) on PD and provide in-depth scientific interpretation about the tradit
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• Liu 2022 Adv Sci (Weinh)
  ...signaling pathways. Cell elongation activates cytosolic phospholipase A2, a nuclear mechanosensor that, when inhibited, hinders AKT phosphorylation, DN
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• Hasenour 2014 J Biol Chem
  ...PK. In contrast, AMPK promotes mitochondrial function and protects against a more precipitous fall in ATP during AICAR administration. |keywords=AICAR, AMP, AMP kinase, AMP-activated kinase (AMPK), Energy metabolism, Fat metabolism, Liver metabolism, ''in vivo''
  3 KB (386 words) - 16:46, 27 March 2018
• Ortega-Dominguez 2017 Food Chem Toxicol
  |title=Ortega-Domínguez B, Aparicio-Trejo OE, García-Arroyo FE, León-Contreras JC, Tapia E, Molina-Jijón E, Hernández-Pando R ...parkin and phosphatase and tensin homologue (PTEN)-induced putative kinase protein 1 (PINK1). In conclusion, the protective effect of curcumin in cisplatin-in
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• Zhou 2018 Free Radic Biol Med
  |title=Zhou L, Yi Y, Yuan Q, Zhang J, Li Y, Wang P, Xu M, Xie S (2018) VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via act ...r cell burden with low systemic toxicity. Thus, our data not only provided a new therapeutic drug candidate for NSCLC, but presented new understanding i
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• Xu 2014 Abstract IOC96
  ...ase ε (IKKε) plays an important role both in inflammation and cancer. As a kinase, IKKε was previously reported to activate the transcription factor NF-кB ...ylation of IRF-3 and production of IFN-β, confirming that the cell line is a perfectly suitable model to study IKKε.
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• Matarne 2015 Abstract MiPschool Greenville 2015
  |title=Chronic activation of AMP-activated protein kinase increases oxidative capacity and monocarboxylate transporter expression in ...r (''P''< 0.05) in the longissimus muscle than the masseter. Further, MCT4 protein expression in the longissimus muscle from AMPKγ3R200Q pigs was greater (''
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• Moreno 2013 Biomed Chromatogr
  |title=Moreno JM, Wojnicz A, Steegman JL, Cano-Abad MF, Ruiz-Nuño A (2013) Imatinib assay by high-performance liquid chromatography in tandem m |authors=Moreno JM, Wojnicz A, Steegman JL, Cano-Abad MF, Ruiz-Nuno A
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• Zambrano 2014 J Cell Biol
  ...ra R, Gómez-Ferrería MA, Pascual A, Buisine N, Sachs LM, Garesse R, Aranda A (2014) The thyroid hormone receptor induces DNA damage and premature senesc ...ra R, Gomez-Ferreria MA, Pascual A, Buisine N, Sachs LM, Garesse R, Aranda A
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• Arandarcikaite 2013 Abstract MiP2013
  ...schemia-induced mitochondrial damages as mediated by activation of protein kinase G. ...the vena cava for 5 min and induced ischemia by keeping isolated brain in a hypoxic chamber for 90 min. To test if the protective effect of NO on brain
  3 KB (436 words) - 11:02, 28 April 2017
• Kerner 2000 Biochim Biophys Acta
  ...hat contact sites between the outer and inner mitochondrial membranes form a microenvironment which facilitates the carnitine transport system. In addit
  2 KB (264 words) - 11:09, 6 July 2021
• Hoepken 2007 Neurobiol Dis
  |title=Hoepken HH, Gispert S, Morales B, Wingerter O, Del Turco D, Mülsch A, Nussbaum RL, Müller K, Dröse S, Brandt U, Deller T, Wirth B, Kudin AP, K |authors=Hoepken HH, Gispert S, Morales B, Wingerter O, Del Turco D, Muelsch A, Nussbaum RL, Mueller K, Droese S, Brandt U, Deller T, Wirth B, Kudin AP, K
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• Schnaitman 1968 J Cell Biol
  ...exhibited a high respiratory rate and respiratory control when assayed in a sucrose-mannitol medium containing EDTA.
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• Ko 2021 Biomolecules
  ...r, our data also indicated that evoking mito-Drp1-Ser637 by protein kinase A (PKA) rather than Drp1-Ser616 by Cdk1/Cyclin B resulted in mitochondrial fi
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