Difference between revisions of "Malate dehydrogenase"
From Bioblast
(Created page with "{{MitoPedia |abbr=MDH |description='''Malate dehydrogenase''' located in the mitochondrial matrix oxidizes malate to oxaloacetate. |info=MiPNet11.04 |type=Enzyme }} {...") |
|||
| (9 intermediate revisions by 4 users not shown) | |||
| Line 1: | Line 1: | ||
{{MitoPedia | {{MitoPedia | ||
|abbr= | |abbr=mtMDH | ||
|description=''' | |description=Mitochondrial '''malate dehydrogenase''' is localized in the mitochondrial matrix and oxidizes [[malate]], generated from fumarate by fumarase, to [[oxaloacetate]], reducing NAD<sup>+</sup> to NADH+H<sup>+</sup> in the [[TCA cycle]]. Malate is added as a substrate in most [[N-pathway control state]]s. | ||
|info=[[ | |info=[[Gnaiger 2020 BEC MitoPathways]] | ||
}} | }} | ||
{{ | |||
| | ::::* Dasika SK, Vinnakota KC, Beard DA (2015) Determination of the catalytic mechanism for mitochondrial malate dehydrogenase. Biophys J 108:408-19. - [[Dasika 2015 Biophys J |»Bioblast link«]] | ||
{{MitoPedia methods}} | |||
{{MitoPedia topics | |||
|mitopedia topic=Enzyme | |||
}} | }} | ||
Latest revision as of 19:36, 1 January 2021
- high-resolution terminology - matching measurements at high-resolution
Malate dehydrogenase
Description
Mitochondrial malate dehydrogenase is localized in the mitochondrial matrix and oxidizes malate, generated from fumarate by fumarase, to oxaloacetate, reducing NAD+ to NADH+H+ in the TCA cycle. Malate is added as a substrate in most N-pathway control states.
Abbreviation: mtMDH
Reference: Gnaiger 2020 BEC MitoPathways
- Dasika SK, Vinnakota KC, Beard DA (2015) Determination of the catalytic mechanism for mitochondrial malate dehydrogenase. Biophys J 108:408-19. - »Bioblast link«
MitoPedia topics: Enzyme
