Difference between revisions of "Malate dehydrogenase"
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{{MitoPedia | {{MitoPedia | ||
|abbr=mtMDH | |abbr=mtMDH | ||
|description=Mitochondrial '''malate dehydrogenase''' is localized in the mitochondrial matrix and oxidizes [[malate]], generated from fumarate by fumarase, to [[oxaloacetate]], reducing NAD<sup>+</sup> to NADH+H<sup>+</sup> in the [[TCA cycle]]. Malate is | |description=Mitochondrial '''malate dehydrogenase''' is localized in the mitochondrial matrix and oxidizes [[malate]], generated from fumarate by fumarase, to [[oxaloacetate]], reducing NAD<sup>+</sup> to NADH+H<sup>+</sup> in the [[TCA cycle]]. Malate is added as a substrate in most [[N-pathway control state]]s. | ||
|info=[[Gnaiger | |info=[[Gnaiger 2020 BEC MitoPathways]] | ||
}} | }} | ||
::::* Dasika SK, Vinnakota KC, Beard DA (2015) Determination of the catalytic mechanism for mitochondrial malate dehydrogenase. Biophys J 108:408-19. - [[Dasika 2015 Biophys J |»Bioblast link«]] | |||
{{MitoPedia methods}} | {{MitoPedia methods}} | ||
{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic=Enzyme | |mitopedia topic=Enzyme | ||
}} | }} | ||
Latest revision as of 19:36, 1 January 2021
- high-resolution terminology - matching measurements at high-resolution
Malate dehydrogenase
Description
Mitochondrial malate dehydrogenase is localized in the mitochondrial matrix and oxidizes malate, generated from fumarate by fumarase, to oxaloacetate, reducing NAD+ to NADH+H+ in the TCA cycle. Malate is added as a substrate in most N-pathway control states.
Abbreviation: mtMDH
Reference: Gnaiger 2020 BEC MitoPathways
- Dasika SK, Vinnakota KC, Beard DA (2015) Determination of the catalytic mechanism for mitochondrial malate dehydrogenase. Biophys J 108:408-19. - »Bioblast link«
MitoPedia topics: Enzyme
