Heimler 2022 MitoFit
Heimler SR, Phang HJ, Bergstrom J, Mahapatra G, Dozier S, Gnaiger E, Molina AJA (2022). Platelet bioenergetics associated with resting metabolic rate and exercise capacity in older women. MitoFit Preprints 2022.7. https://doi.org/10.26124/mitofit:2022-0007 |
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[Platelet bioenergetics associated with resting metabolic rate and exercise capacity in older women]
Heimler Stephanie R, Phang Howard J, Bergstrom Jaclyn, Mahapatra Gargi, Dozier Stephen, Gnaiger Erich, Molina Anthony JA (2022-04-) MitoFit Prep
Abstract: This study investigates relationships between platelet mitochondrial bioenergetics and resting metabolic rate (RMR), body composition, and exercise fitness in women over 60 years of age. We report positive correlations between peak respiratory exchange ratio (RER) and RMR with five measures of platelet respiration, supporting the premise that blood cells can be utilized to report on mitochondrial function associated with physical health and fitness. Identifying mechanisms associated with physical performance among older adults supports the development of reliable biomarkers of healthy aging and can advance the development of efficacious interventions.
β’ Keywords: platelets, resting metabolic rate RMR, cardiopulmonary exercise testing, OXPHOS capacity P, electron transfer capacity E, inverted regression analysis
β’ Bioblast editor: Tindle-Solomon L
β’ O2k-Network Lab: AT Innsbruck Oroboros
In prep
ORCID: Heimler Stephanie R, Phang Howard J, Mahapatra Gargi, Gnaiger Erich, Molina Anthony JA
Labels: MiParea: Respiration, Exercise physiology;nutrition;life style
Organism: Human
Tissue;cell: Blood cells
Preparation: Permeabilized cells
Coupling state: OXPHOS, ET
Pathway: F, N, S, Gp, ROX
HRR: Oxygraph-2k