Difference between revisions of "DE Duesseldorf Roden M"
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{{O2k-Network Lab | {{O2k-Network Lab | ||
|institution= | |institution=German Diabetes CenterHeinrich Heine University DĂŒsseldorfLeibniz Institute for Diabetes Research'''Oroboros O2k-Training Centre''' | ||
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|address=Auf'm Hennekamp 65 | |address=Auf'm Hennekamp 65 | ||
|area code=40225 | |area code=40225 | ||
|city=Duesseldorf | |city=Duesseldorf | ||
|country=Germany | |country=Germany | ||
|weblink=[ | |weblink=[https://ddz.de/en/ DDZ] | ||
|Contact=Roden Michael | |Contact=Roden Michael | ||
|MiPNetLab=Esser Myrko, Jelenik Tomas, Kaul Kirti, Koliaki Chrysi, | |MiPNetLab=Bohmeier Maria, Duerrschmidt Olga, Esser Myrko, Granata Cesare, Jelenik Tomas, Kaul Kirti, Koliaki Chrysi, Saatmann Nina, Schrage-Knoll Irmtrud | ||
|Team previous=Guelden Elke, Janke Linda, Pesta | |Team previous=Guelden Elke, Janke Linda, Pesta Dominik, Phielix Esther, Sequaris Gilles, Szendroedi Julia | ||
|Status=[[Power-O2k|''' | |Status=[[Power-O2k|''' 9 Power-O2k''']] '''O2k-Training Centre''', 2009- | ||
|info=[ | |info=[[MiPNet28.02_IOC162_Schroecken_AT| IOC162 Schroecken AT]], [[MiPNet25.16 Virtual O2k-Workshop HRR| Virtual O2k-Workshop]], [[MitoEAGLE Obergurgl 2019-01-31| MitoEAGLE 2019]], [[MitoEAGLE Copenhagen 2018| MitoEAGLE 2018]], [[MitoFit Science Camp 2016 Kuehtai AT| MitoFit Science Camp 2016]], [[IOC95]], [[MiP2014]], [[MiP2013]], [[IOC79]], [[IOC74]], [[Bioblast 2012]], [[IOC66]], [[IOC65]], [[IOC61]], [[IOC60]], [[IOC56]], [[IOC55]], [[IOC54]], [[IOC53]], [[IOC50]], [[MiPNet12.14 IOC39|IOC39]], [[MiPNet11.02 IOC32|IOC32]] | ||
|Info=[http://www.oroboros.at/index.php?id=1221 DE_Duesseldorf_RodenM] | |Info=[http://www.oroboros.at/index.php?id=1221 DE_Duesseldorf_RodenM] | ||
}} | }} |
Latest revision as of 14:47, 16 October 2023
DE Duesseldorf Roden M
O2k-Network Lab | German Diabetes CenterHeinrich Heine University DĂŒsseldorfLeibniz Institute for Diabetes ResearchOroboros O2k-Training Centre |
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Address | Auf'm Hennekamp 65, 40225 |
City | Duesseldorf |
State/Prov | |
Country | Germany |
Weblink | DDZ |
Contact | Roden Michael |
Team | Bohmeier Maria, Duerrschmidt Olga, Esser Myrko, Granata Cesare, Jelenik Tomas, Kaul Kirti, Koliaki Chrysi, Saatmann Nina, Schrage-Knoll Irmtrud |
Team previous | Guelden Elke, Janke Linda, Pesta Dominik, Phielix Esther, Sequaris Gilles, Szendroedi Julia |
Status | 9 Power-O2k O2k-Training Centre, 2009- |
Oroboros Events | IOC162 Schroecken AT, Virtual O2k-Workshop, MitoEAGLE 2019, MitoEAGLE 2018, MitoFit Science Camp 2016, IOC95, MiP2014, MiP2013, IOC79, IOC74, Bioblast 2012, IOC66, IOC65, IOC61, IOC60, IOC56, IOC55, IOC54, IOC53, IOC50, IOC39, IOC32 |
Topics |
O2k-Publications
Published | Reference | |
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Zweck 2023 ESC Heart Fail | 2023 | Zweck E, Karschnia M, Scheiber D, Heidecke H, Dechend R, Barthuber C, Kaufmann S, Kelm M, Roden M, Westenfeld R, Szendrödi J, Boege F (2023) Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure. https://doi.org/10.1002/ehf2.14293 |
Dewidar 2023 EBioMedicine | 2023 | Dewidar B, Mastrototaro L, Englisch C, Ress C, Granata C, Rohbeck E, Pesta D, Heilmann G, Wolkersdorfer M, Esposito I, Reina Do Fundo M, Zivehe F, Yavas A, Roden M (2023) Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases. https://doi.org/10.1016/j.ebiom.2023.104714 |
Bodis 2023 Diabetes Obes Metab | 2023 | Bódis K, Breuer S, Crepzia-Pevzner A, Zaharia OP, Schön M, Saatmann N, Altenhofen D, Springer C, Szendroedi J, Wagner R, Al-Hasani H, Roden M, Pesta D, Chadt A (2023) Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model. https://doi.org/10.1111/dom.15322 |
Jelenik 2022 Pharmacol Res | 2022 | Jelenik T, Kodde A, Pesta D, Phielix E, Oosting A, Rohbeck E, Dewidar B, Mastrototaro L, Trenkamp S, Keijer J, van der Beek EM, Roden M (2022) Dietary lipid droplet structure in postnatal life improves hepatic energy and lipid metabolism in a mouse model for postnatal programming. https://doi.org/10.1016/j.phrs.2022.106193 |
Sarabhai 2022 Diabetologia | 2022 | Sarabhai T, Mastrototaro L, Kahl S, Bönhof GJ, Jonuscheit M, Bobrov P, Katsuyama H, Guthoff R, Wolkersdorfer M, Herder C, Meuth SG, Dreyer S, Roden M (2022) Hyperbaric oxygen rapidly improves tissue-specific insulin sensitivity and mitochondrial capacity in humans with type 2 diabetes: a randomised placebo-controlled crossover trial. https://doi.org/10.1007/s00125-022-05797-0 |
Gancheva 2022 Diabetes Care | 2022 | Gancheva S, Kahl S, Pesta D, Mastrototaro L, Dewidar B, Strassburger K, Sabah E, Esposito I, WeiĂ J, Sarabhai T, Wolkersdorfer M, Fleming T, Nawroth P, Zimmermann M, Reichert AS, Schlensak M, Roden M (2022) Impaired hepatic mitochondrial capacity in nonalcoholic steatohepatitis associated with type 2 diabetes. https://doi.org/10.2337/dc21-1758 |
Apostolopoulou 2021 Sci Adv | 2021 | Apostolopoulou M, Mastrototaro L, Hartwig S, Pesta D, StraĂburger K, de Filippo E, Jelenik T, Karusheva Y, Gancheva S, Markgraf D, Herder C, Nair KS, Reichert AS, Lehr S, MĂŒssig K, Al-Hasani H, Szendroedi J, Roden M (2021) Metabolic responsiveness to training depends on insulin sensitivity and protein content of exosomes in insulin-resistant males. https://doi.org/10.1126/sciadv.abi9551 |
Sarabhai 2021 Diabetologia | 2021 | Sarabhai T, Koliaki C, Mastrototaro L, Kahl S, Pesta D, Apostolopoulou M, Wolkersdorfer M, Bönner AC, Bobrov P, Markgraf DF, Herder C, Roden M (2021) Dietary palmitate and oleate differently modulate insulin sensitivity in human skeletal muscle. Diabetologia 65:301-14. |
Zweck 2021 Diabetes Care | 2021 | Zweck E, Scheiber D, Jelenik T, Bönner F, Horn P, Pesta D, Schultheiss HP, Boeken U, Akhyari P, Lichtenberg A, Kelm M, Roden M, Westenfeld R, Szendroedi J (2021) Exposure to type 2 diabetes provokes mitochondrial impairment in apparently healthy human hearts. Diabetes Care 44:e82-e84. |
Hoppel 2021 Front Physiol | 2021 | Hoppel F, Calabria E, Pesta DH, Kantner-Rumplmair W, Gnaiger E, Burtscher M (2021) Effects of ultramarathon running on mitochondrial function of platelets and oxidative stress parameters: a pilot study. https://doi.org/10.3389/fphys.2021.632664 |
Pesta 2021 Front Endocrinol (Lausanne) | 2021 | Pesta D, Jelenik T, Zaharia OP, Bobrov P, Görgens S, BĂłdis K, Karusheva Y, Krako Jakovljevic N, Lalic NM, Markgraf DF, Burkart V, MĂŒssig K, Knebel B, Kotzka J, Eckel J, Strassburger K, Szendroedi J, Roden M (2021) NDUFB6 polymorphism is associated with physical activity-mediated metabolic changes in type 2 diabetes. https://doi.org/10.3389/fendo.2021.693683 |
Schumann 2021 Commun Biol | 2021 | Schumann T, Koenig J, von Loeffelholz C, Vatner DF, Zhang D, Perry RJ, Bernier M, Chami J, Henke C, Kurzbach A, El-Agroudy NN, Willmes DM, Pesta D, de Cabo R, O Sullivan JF, Simon E, Shulman GI, Hamilton BS, Birkenfeld AL (2021) Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance. Commun Biol 4:826. |
Hoppel 2021 Cells | 2021 | Hoppel F, Garcia-Souza LF, Kantner-Rumplmair W, Burtscher M, Gnaiger E, Pesta D, Calabria E (2021) Human platelet mitochondrial function reflects systemic mitochondrial alterations: a protocol for application in field studies. https://doi.org/10.3390/cells10082088 |
Doerrier 2019 MitoFit Preprint Arch EA | 2019 | Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2019) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. https://doi.org/10.26124/mitofit:ea19.MiPSchool.0009 |
Simon 2019 J Biol Chem | 2019 | Simon MC, Reinbeck AL, Wessel C, Heindirk J, Jelenik T, Kaul K, Arreguin-Cano J, Strom A, Blaut M, BĂ€ckhed F, Burkart V, Roden M (2019) Distinct alterations of gut morphology and microbiota characterize accelerated diabetes onset in non-obese diabetic mice. J Biol Chem 295:969-80. |
Chabi 2019 MitoFit Preprint Arch EA | 2019 | Chabi BĂ©atrice, Ost M, Gama-Perez P, Dahdah N, Lemieux H, Holody CD, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Pesta D, Calabria E, Casado M, Fernandez-Ortiz M, Acuña-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, WĂŒst R, Dayanidhi S, Gnaiger E, Doerrier C, Garcia-Roves PM (2019) Generating reference values on mitochondrial respiration in permeabilized muscle fibers. https://doi.org/10.26124/mitofit:ea19.MitoEAGLE.0001 |
Bodis 2019 J Clin Endocrinol Metab | 2019 | Bodis K, Jelenik T, Lundbom J, Markgraf DF, Strom A, Zaharia OP, Karusheva Y, Burkart V, Muessig K, Kupriyanova Y, Ouni M, Wolkersdorfer M, Hwang JH, Ziegler D, Schuermann A, Roden M, Szendroedi J (2019) Expansion and impaired mitochondrial efficiency of deep subcutaneous adipose tissue in recent-onset type 2 diabetes. J Clin Endocrinol Metab 105:dgz267. |
Gancheva 2019 Nat Commun | 2019 | Gancheva S, Ouni M, Jelenik T, Koliaki C, Szendroedi J, Toledo FGS, Markgraf DF, Pesta DH, Mastrototaro L, De Filippo E, Herder C, JĂ€hnert M, Weiss J, Strassburger K, Schlensak M, SchĂŒrmann A, Roden M (2019) Dynamic changes of muscle insulin sensitivity after metabolic surgery. Nat Commun 10:4179. |
Grandoch 2019 Nat Metab | 2019 | Grandoch M, Flögel U, Virtue S, Maier JK, Jelenik T, Kohlmorgen C, Feldmann K, Ostendorf Y, Castañeda TR, Zhou Z, Yamaguchi Y, Nascimento EBM, Sunkari VG, Goy C, Kinzig M, Sörgel F, Bollyky PL, Schrauwen P, Al-Hasani H, Roden M, Keipert S, Vidal-Puig A, Jastroch M, Haendeler J, Fischer JW (2019) 4-Methylumbelliferone improves the thermogenic capacity of brown adipose tissue. Nat Metab 1:546-59. |
Karusheva 2019 Am J Clin Nutr | 2019 | Karusheva Y, Koessler T, Strassburger K, Markgraf D, Mastrototaro L, Jelenik T, Simon MC, Pesta D, Zaharia OP, BĂłdis K, BĂ€renz F, Schmoll D, Wolkersdorfer M, Tura A, Pacini G, Burkart V, MĂŒssig K, Szendroedi J, Roden M (2019) Short-term dietary reduction of branched-chain amino acids reduces meal-induced insulin secretion and modifies microbiome composition in type 2 diabetes: a randomized controlled crossover trial. Am J Clin Nutr 110:1098-107. |
Scheiber 2019 Exp Mol Med | 2019 | Scheiber D, Jelenik T, Zweck E, Horn P, Schultheiss HP, Lassner D, Boeken U, Saeed D, Kelm M, Roden M, Westenfeld R, Szendroedi J (2019) High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure. Exp Mol Med 51:16. |
Gratl 2019 Eur J Vasc Endovasc Surg | 2019 | Gratl A, Frese J, Speichinger F, Pesta D, Frech A, Omran S, Greiner A (2019) Regeneration of mitochondrial function in gastrocnemius muscle in peripheral arterial disease after successful revascularisation. Eur J Vasc Endovasc Surg 59:109-15. |
Scheiber 2018 J Cardiovasc Transl Res | 2018 | Scheiber D, Zweck E, Jelenik T, Horn P, Albermann S, Masyuk M, Boeken U, Saeed D, Kelm M Roden M, Szendroedi J, Westenfeld R (2018) Reduced myocardial mitochondrial ROS production in mechanically unloaded hearts. J Cardiovasc Transl Res 12:107-15. |
Jelenik 2018 Mol Metab | 2018 | Jelenik T, Dille M, MĂŒller-LĂŒhlhoff S, Kabra DG, Zhou Z, Binsch C, Hartwig S, Lehr S, Chadt A, Peters EMJ, Kruse J, Roden M, Al-Hasani H, Castañeda TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38. |
Jelenik 2018 Diabetes | 2018 | Jelenik T, Flögel U, Ălvarez-HernĂĄndez E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, MĂŒller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702. |
Fischer 2018 BMC Musculoskelet Disord | 2018 | Fischer MJ, Horvath G, Krismer M, Gnaiger E, Goebel G, Pesta DH (2018) Evaluation of mitochondrial function in chronic myofascial trigger points - a prospective cohort pilot study using high-resolution respirometry. BMC Musculoskelet Disord 19:388. |
Wolff 2017 Thesis | 2017 | Wolff C (2017) Impact of lipid metabolism on skeletal muscle mitochondrial function in type 2 diabetes mellitus patients. Dissertation p68. |
Jelenik 2017 Diabetes | 2017 | Jelenik T, Kaul K, SĂ©quaris G, Flögel U, Phielix E, Kotzka J, Knebel B, Fahlbusch P, Hörbelt T, Lehr S, Reinbeck AL, MĂŒller-Wieland D, Esposito I, Shulman GI, Szendroedi J, Roden M (2017) Mechanisms of insulin resistance in primary and secondary nonalcoholic fatty liver. Diabetes 66:2241-53. |
Pesta 2016 FASEB J | 2016 | Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI (2016) Hypophosphatemia promotes lower rates of muscle ATP synthesis. FASEB J 30:3378-87. |
Sparks 2016 Diabetologia | 2016 | Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J (2016) ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia 59:1030-9. |
Fritsch 2015 Am J Clin Nutr | 2015 | Fritsch M, Koliaki C, Livingstone R, Phielix E, Bierwagen A, Meisinger M, Jelenik T, Strassburger K, Zimmermann S, Brockmann K, Wolff C, Hwang JH, Szendroedi J, Roden M (2015) Time course of postprandial hepatic phosphorus metabolites in lean, obese, and type 2 diabetes patients. Am J Clin Nutr 102:1051-8. |
Van de Weijer 2015 Diabetes | 2015 | van de Weijer T, Phielix E, Bilet L, Williams EG, Ropelle ER, Bierwagen A, Livingstone R, Nowotny P, Sparks LM, Paglialunga S, Szendroedi J, Havekes B, Moullan N, Pirinen E, Hwang JH, Schrauwen-Hinderling VB, Hesselink MK, Auwerx J, Roden M, Schrauwen P (2015) Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans. Diabetes 64:1193-201. |
Koliaki 2015 Cell Metab | 2015 | Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M (2015) Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 21:739-46. |
Phielix 2014 Diabetologia | 2014 | Phielix E, Jelenik T, Nowotny P, Szendroedi J, Roden M (2014) Reduction of non-esterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial. Diabetologia 57:572-81. |
Jelenik 2014 Diabetes | 2014 | Jelenik T, SĂ©quaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, WeiĂ J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M (2014) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67. |
Jelenik 2014 Diabetologie und Stoffwechsel | 2014 | Jelenik T, Bottermann K, Moellendorf S, Goedecke A, Kotzka J, Kelm M, Roden M, Szendroedi J (2014) Mice with insulin resistance and non-alcoholic fatty liver are characterized by cardiac hypertrophy and increased oxidative stress. Diabetologie und Stoffwechsel 9:250. |
Jelenik 2013 Eur Heart J | 2013 | Jelenik T, Floegel U, Phielix E, Kaul K, Nowotny P, Partke HP, Schrader J, Roden M, Szendroedi S (2013) Non-alcoholic fatty liver disease and insulin resistance are associated with increased cardiac oxidative stress in mice. Eur Heart J 34:P5045. |
Jelenik 2013 Antioxid Redox Signal | 2013 | Jelenik T, Roden M (2013) Mitochondrial plasticity in obesity and diabetes mellitus. Antioxid Redox Signal 19:258-68. |
Phielix 2012 Diabetes | 2012 | Phielix E, Meex R, Ouwens DM, Sparks LM, Hoeks J, Schaart G, Moonen-Kornips E, Hesselink MK, Schrauwen P (2012) High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance. Diabetes 61:2472-8. |
Szendroedi 2011 Nat Rev Endocrinol | 2011 | Szendroedi J, Phielix E, Roden M (2011) The role of mitochondria in insulin resistance and type 2 diabetes mellitus. Nat Rev Endocrinol 8:92-103. |
O2k-Abstracts
Published | Reference | |
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Granata 2022 Abstract Bioblast | 2022 | 3.3. «5 min» Granata Cesare (2022) Exercise training-induced enhancement of electron flow in the OXPHOS system is more important than increasing the OXPHOS machinery content to improve ATP generation in human skeletal muscle. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 ![]() |
Doerrier 2020 PaduaMuscleDays Poster | 2020 | Doerrier C, Gama-Perez P, Chabi B, Ost M, Distefano G, Pesta D, Dahdah N, Lemieux H, Holody C, Carpenter RG, Tepp K, Puurand M, Kaambre T, Dubouchaud H, Cortade F, Calabria E, Casado M, Fernandez-Ortiz M, Acuna-Castroviejo D, Villena JA, Grefte S, Keijer J, O'Brien K, Sowton A, Murray AJ, Campbell MD, Marcinek DJ, Nollet E, Wuest R, Dayanidhi S, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen PM, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Commitment to reproducibility in mitochondrial respiration studies with permeabilized muscle fibers. PaduaMuscleDays. |
Chabi 2019 MiP2019 | 2019 | Generating reference values on mitochondrial respiration in permeabilized muscle fibers. |
Horn 2018 Eur Heart J | 2018 | Horn P, Haschemi J, Scheiber D, Szendroedi J, Zweck E, Sun R, Luppa PB, Saeed D, Boeken U, Kelm M, Roden M, Boege F, Westenfeld R (2018) Sympathomimetic beta-1AR autoantibodies in patients after heart transplantation are associated with higher mitochondrial coupling efficiency. Eur Heart J. |
Doerrier 2018 MiP2018c | 2018 | Inter-laboratory study on human permeabilized myofibers: effects of fiber preparation, respiration buffer, and blebbistatin on mitochondrial respiratory capacity and oxygen limitation. |
Garcia-Roves 2018 MiP2018b | 2018 | Generating mitochondrial respirometry reference values from permeabilized mouse soleus muscle fibers. Working Group 2 report. Garcia-Roves_Presentation |
Scheiber 2017 Europ Heart J | 2017 | High-resolution respirometry in human endomyocardial biopsies to assess myocardial mitochondrial function. |