Van Bree 2014 PhD Thesis
|van Bree B (2014) Mitochondria, lipotoxicity and skeletal muscle metabolism: implications for type 2 diabetes mellitus. PhD Thesis 1-150.|
Abstract: Every cell in living organisms depends on adenosine triphosphate (ATP) as a primary energy source required for biochemical and physiological processes. Mitochondria are the most important organelles for energy production by generating ATP through the electron transport chain (ETC) located in the inner mitochondrial membrane (IMM). Via the food we eat, especially carbohydrates and lipids, substrates for mitochondria are provided that can be used for ATP production. These substrates are mainly degraded in the mitochondrial matrix, the center of mitochondria that is surrounded by the IMM.
• Keywords: Amplex Red
• O2k-Network Lab: NL Maastricht Schrauwen P
Labels: MiParea: Respiration, Exercise physiology;nutrition;life style Pathology: Diabetes Stress:Oxidative stress;RONS Organism: Mouse Tissue;cell: Skeletal muscle Preparation: Isolated mitochondria
Coupling state: LEAK, OXPHOS, ET Pathway: F, N HRR: Oxygraph-2k