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Tranah 2011 Mitochondrion

From Bioblast
Publications in the MiPMap
Tranah GJ, Manini TM, Lohman KK, Nalls MA, Kritchevsky S, Newman AB, Harris TB, Miljkovic I, Biffi A, Cummings SR, Liu Y (2011) Mitochondrial DNA variation in human metabolic rate and energy expenditure. Mitochondrion 11:855-61.

Β» PMID: 21586348 Open Access

Tranah GJ, Manini TM, Lohman KK, Nalls MA, Kritchevsky S, Newman AB, Harris TB, Miljkovic I, Biffi A, Cummings SR, Liu Y (2011) Mitochondrion

Abstract: The role of climate in driving selection of mtDNA as Homo sapiens migrated out of Africa into Eurasia remains controversial. We evaluated the role of mtDNA variation in resting metabolic rate (RMR) and total energy expenditure (TEE) among 294 older, community-dwelling African and European American adults from the Health, Aging and Body Composition Study. Common African haplogroups L0, L2 and L3 had significantly lower RMRs than European haplogroups H, JT and UK with haplogroup L1 RMR being intermediate to these groups. This study links mitochondrial haplogroups with ancestry-associated differences in metabolic rate and energy expenditure.


Labels: MiParea: mtDNA;mt-genetics, Comparative MiP;environmental MiP 


Organism: Human