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Gonçalves 2019 Mitofit Preprint Arch EA
Additional label Preprints  +
Has abstract Version 1 ('''v1''') '''2019-06-03''' [htt
Version 1 ('''v1''') '''2019-06-03''' [http://wiki.oroboros.at/images/0/0a/Goncalves_2019_MitoFit_Preprint_Arch_doi_10.26124mitofitEA19.MiPSchool.0002.pdf doi:10.26124/mitofit:ea19.MiPSchool.0002] Parkinson disease (PD) is considered the second most common neurodegenerative disorder in the world and is related mainly with aging. PD is characterized by loss of dopaminergic neurons and formation of protein aggregates, such as α-synuclein [1], leading to motor dysfunction, and impairment of cognitive and memory functions [2]. The pathology and symptoms of PD are well described, although its mechanisms and causes remain unclear. One mechanism involved in PD is mitochondrial dysfunction [3]. Mutation in genes involved in mitochondrial quality control, such as PARK2 and Pink1, produce PD symptoms [4]. These genes code for proteins such as PINK1 (PTEN induced kinase 1) that is a serine/threonine kinase involved in mitochondrial network quality control [5]. In this work we evaluated mitochondrial quality control using Pink1 knockout of Drosophila melanogaster in different lifetime.
ophila melanogaster in different lifetime.  +
Has editor [[Iglesias-Gonzalez J]]  +
Has info [[File:MitoFit Preprint Arch pdf.png|left|
[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/0/0a/Goncalves_2019_MitoFit_Preprint_Arch_doi_10.26124mitofitEA19.MiPSchool.0002.pdf|MitoFit pdf]] <big><big>'''[http://www.mitofit.org/images/0/0a/Goncalves_2019_MitoFit_Preprint_Arch_doi_10.26124mitofitEA19.MiPSchool.0002.pdf Aging effects on mitochondrial control factors in Pink1 knockout Drosophila melanogaster]'''</big></big> <br />
r]'''</big></big> <br />  +
Has publicationkeywords PARK2 & PINK1  +
Has title Gonçalves Debora F, Courtes AA, Hartmann D
Gonçalves Debora F, Courtes AA, Hartmann DD, Carvalho PR, Marques DM, Machado ML, Furtado AV, Soares FA, Dalla Corte CL (2019) Aging effects on mitochondrial control factors in Pink1 knockout Drosophila melanogaster. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0002]].
oi:10.26124/mitofit:ea19.MiPSchool.0002]].  +
Was published in journal MitoFit Preprint Arch +
Was published in year 2019  +
Was written by Courtes AA + , Hartmann DD + , Carvalho PR + , Marques DM + , Machado ML + , Furtado AV + , Soares FAA + , Dalla Corte CL + , Goncalves DF +
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Gonçalves 2019 Mitofit Preprint Arch EA  +
Categories MitoFit , Publications
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"Modification date" is a predefined property that corresponds to the date of the last modification of a subject and is provided by Semantic MediaWiki.
06:47:55, 19 June 2019  +
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