Renner 2003 Biochim Biophys Acta
|Renner K, Amberger A, Konwalinka G, Gnaiger E (2003) Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells. Biochim Biophys Acta 1642:115-23.|
These results, therefore, provide conclusive evidence that alterations in respiratory capacity and enzyme activities per cell are mainly caused by opposite changes in cell size, occurring upon cell cycle arrest triggered by dexamethasone and gemcitabine in the early phase of apoptosis.
• Keywords: Apoptosis, Dexamethasone, Gemcitabine, Mitochondrial respiratory control, Cell cycle
Labels: MiParea: Respiration, mt-Biogenesis;mt-density, Genetic knockout;overexpression, Pharmacology;toxicology Pathology: Cancer Stress:Cell death Organism: Human Tissue;cell: Blood cells Preparation: Intact cells, Permeabilized cells, Enzyme, Oxidase;biochemical oxidation
Regulation: Coupling efficiency;uncoupling, Cyt c Coupling state: ROUTINE, ET
- Referred to in Gnaiger_2014_MitoPathways, Chapter 1.