From Bioblast
- COST Action CA15203 MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
- COST Action CA15203 MitoEAGLE
Piel S
MitoPedia topics: EAGLE
COST WG4: WG4
Name | Piel Sarah, Dr. |
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Institution | Anesthesia and Critical Care,
The Children’s Hospital of Philadelphia, US |
Address | 3401 Civic Center Blvd, 19104 |
City | Philadelphia |
State/Province | Pennsylvania (PA) |
Country | USA |
piels@email.chop.edu | |
Weblink | |
O2k-Network Lab | SE Lund Elmer E, US PA Philadelphia Kilbaugh T |
Labels:
Field of research: Basic
Topics: Pharmacological modification of mitochondria. Drug Toxicity
Publications
Published | Reference | |
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Gnaiger 2019 MitoFit Preprint Arch | 2019 | Gnaiger E, Aasander Frostner E, Abdul Karim N, Abdel-Rahman EA, Abumrad NA, Acuna-Castroviejo D, Adiele RC, et al (2019) Mitochondrial respiratory states and rates. MitoFit Preprint Arch doi:10.26124/mitofit:190001.v6. |
MitoEAGLE blood cells 1 | 2018 | MitoEAGLE blood cells group (2018) An interlaboratory guide through procedures for mitochondrial respiratory studies with intact and permeabilized peripheral blood mononuclear cells and platelets. - Updated: 2018-02-23 |
Piel 2018 Intensive Care Med Exp | 2018 | Piel S, Ehinger JK, Chamkha I, Frostner EÅ, Sjövall F, Elmér E, Hansson MJ (2018) Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production. Intensive Care Med Exp 6:22. |
Elmer 2017 US Patent | 2017 | Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1. |
McCourt 2016 PLOS ONE | 2016 | McCourt AC, Jakobsson L, Larsson S, Holm C, Piel S, Elmér E, Björkqvist M (2016) White adipose tissue browning in the R6/2 mouse model of Huntington's disease. PLOS ONE 11:e0159870. |
Karlsson 2016 Mitochondrion | 2016 | Karlsson M, Ehinger JK, Piel S, Sjövall F, Henriksnäs J, Höglund U, Hansson MJ, Elmér E (2016) Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – an in vivo large animal model. Mitochondrion 31:56-62. |
Ehinger 2016 Nat Commun | 2016 | Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, Elmér E (2016) Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency. Nat Commun 7:12317. |
Piel 2014 Acta Physiol (Oxf) | 2014 | Piel S, Ehinger JK, Elmér E, Hansson Magnus J (2014) Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition. Acta Physiol (Oxf) 213:171-80. |
Abstracts
Published | Reference | |
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Calabria 2019 MiPschool Coimbra | 2019 | Investigating mitochondrial function in blood cells by high-resolution respirometry: contribution to an interlaboratory study. Mitoeagle WG4. |
Janowska 2018 IOC134 | 2018 | Mitochondrial targeted biofuels as countermeasures against chemical threats. |
Aasander Frostner 2017 MiP2017 | 2017 | Cell-permeable succinate and malonate as research tools. Aasander Frostner_Poster |
Ehinger 2015 Abstract MiPschool London 2015 | 2015 | Cell-permeable mitochondrial complex II substrates – a new compound class for treatment of complex I-linked mitochondrial disease. |
Piel 2015 Abstract MiPschool London 2015 | 2015 | The novel Cyclophilin D inhibitor NVP019 reduces mitochondrial permeability transition in isolated rat and human heart mitochondria. |