Piel S

News and Events

About COST Action MitoEAGLE

Working Groups

MiP/MitoEAGLE Conference, WG and MC Meeting 2019 Belgrade RS

MitoEAGLE Preprint States and rates

Short-Term Scientific Missions

Inclusiveness Target Countries

Management Committee

Members

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COST Action CA15203 MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping

 

Piel S

MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1

COST WG4: WG4

Name	Piel Sarah, Dr.
Institution	Anesthesia and Critical Care, The Children’s Hospital of Philadelphia, US
Address	3401 Civic Center Blvd, 19104
City	Philadelphia
State/Province	Pennsylvania (PA)
Country	USA
Email	piels@email.chop.edu
Weblink
O2k-Network Lab	SE Lund Elmer E, US PA Philadelphia Kilbaugh T

Labels: Field of research: Basic  Topics: Pharmacological modification of mitochondria. Drug Toxicity 

Publications

	Published	Reference
Gnaiger 2019 MitoFit Preprint Arch	2019	Gnaiger E, Aasander Frostner E, Abdul Karim N, Abdel-Rahman EA, Abumrad NA, Acuna-Castroviejo D, Adiele RC, et al (2019) Mitochondrial respiratory states and rates. MitoFit Preprint Arch doi:10.26124/mitofit:190001.v4.
MitoEAGLE blood cells 1	2018	MitoEAGLE blood cells group (2018) An interlaboratory guide through procedures for mitochondrial respiratory studies with intact and permeabilized peripheral blood mononuclear cells and platelets. - Updated: 2018-02-23
Piel 2018 Intensive Care Med Exp	2018	Piel S, Ehinger JK, Chamkha I, Frostner EÅ, Sjövall F, Elmér E, Hansson MJ (2018) Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production. Intensive Care Med Exp 6:22.
Elmer 2017 US Patent	2017	Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1.
Karlsson 2016 Mitochondrion	2016	Karlsson M, Ehinger JK, Piel S, Sjövall F, Henriksnäs J, Höglund U, Hansson MJ, Elmér E (2016) Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – an in vivo large animal model. Mitochondrion 31:56-62.
Ehinger 2016 Nat Commun	2016	Ehinger JK, Piel S, Ford R, Karlsson M, Sjövall F, Frostner EÅ, Morota S, Taylor RW, Turnbull DM, Cornell C, Moss SJ, Metzsch C, Hansson MJ, Fliri H, Elmér E (2016) Cell-permeable succinate prodrugs bypass mitochondrial complex I deficiency. Nat Commun 7:12317.
McCourt 2016 PLOS ONE	2016	McCourt AC, Jakobsson L, Larsson S, Holm C, Piel S, Elmér E, Björkqvist M (2016) White adipose tissue browning in the R6/2 mouse model of Huntington's disease. PLOS ONE 11:e0159870.
Piel 2014 Acta Physiol (Oxf)	2014	Piel S, Ehinger JK, Elmér E, Hansson Magnus J (2014) Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial complex I inhibition. Acta Physiol (Oxf) 213:171-80.

Abstracts

	Published	Reference
Calabria 2019 MiPschool Coimbra	2019	Investigating mitochondrial function in blood cells by high resolution respirometry: contribution to an interlaboratory study. Mitoeagle WG4.
Janowska 2018 IOC134	2018	Mitochondrial targeted biofuels as countermeasures against chemical threats.
Aasander Frostner 2017 MiP2017	2017	Cell-permeable succinate and malonate as research tools. Aasander Frostner_Poster
Piel 2015 Abstract MiPschool London 2015	2015	The novel Cyclophilin D inhibitor NVP019 reduces mitochondrial permeability transition in isolated rat and human heart mitochondria.
Ehinger 2015 Abstract MiPschool London 2015	2015	Cell-permeable mitochondrial complex II substrates – a new compound class for treatment of complex I-linked mitochondrial disease.

Participated at

• MitoEAGLE 2018 Lund SE
• MitoEAGLE 2018 Poznan PL
• IOC113 Havana CU
• IOC75 Schroecken AT