Nolfi-Doneganab 2020 Redox Biol
| Nolfi-Doneganab D, Braganzaa A, Shivaac S (2020) Mitochondrial electron transport: oxidative phosphorylation, mitochondrial oxidant production, and methods of measurement. Redox Biol 2020:101674. |
Nolfi-Doneganab Deirdre, Braganzaa Andrea, Shivaac Sruti (2020) Redox Biol
Abstract: The mitochondrial electron transport chain utilizes a series of electron transfer reactions to generate cellular ATP through oxidative phosphorylation. A consequence of electron transfer is the generation of reactive oxygen species (ROS), which contributes to both homeostatic signaling as well as oxidative stress during pathology. In this graphical review we provide an overview of oxidative phosphorylation and its inter-relationship with ROS production by the electron transport chain. We also outline traditional and novel translational methodology for assessing mitochondrial energetics in health and disease.
• Bioblast editor: Plangger M
Labels: MiParea: Respiration, Instruments;methods
Stress:Oxidative stress;RONS
HRR: Oxygraph-2k
2020-08
