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Hamilton 2013 Methodist Debakey Cardiovasc J

From Bioblast
Publications in the MiPMap
Hamilton DJ (2013) Mechanisms of disease: is mitochondrial function altered in heart failure? Methodist Debakey Cardiovasc J 9:44-8.

Β» PMID: 23519321 Open Access

Hamilton DJ (2013) Methodist Debakey Cardiovasc J

Abstract: The human heart sustains an exceptional energy transfer rate, consuming more energy per gram weight than any other organ system. The healthy heart can rapidly adapt to changes in demand, while the failing heart cannot. Cardiac energy flux systems falter in the failing heart. The purpose of this review is to characterize the fundamental role of mitochondria in this energy transfer system and describe our local research on mitochondrial respiratory capacity in failing human hearts. β€’ Keywords: Heart failure, Mitochondria, Myocardial energetics, Oxidative phosphorylation, Oximetry, Respiratory capacity


Labels: MiParea: mt-Medicine  Pathology: Cardiovascular 

Organism: Human  Tissue;cell: Heart 



HRR: Oxygraph-2k 

Review