Garcia JA
From Bioblast
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O2k-Network Lab |
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Publications
Published | Reference | |
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Doerrier 2016 Mitochondrion | 2016 | Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63. |
Volt 2016 J Pineal Res | 2016 | Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205. |
Garcia 2015 FASEB J | 2015 | García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75. |
Ortiz 2015 J Pineal Res | 2015 | Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49. |
Doerrier 2014 Life Sci | 2014 | Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65. |
Ortiz 2014 J Pineal Res | 2014 | Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sánchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81. |
Garcia-Corzo 2013 Hum Mol Genet | 2013 | García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48. |
Acuña-Castroviejo 2011 Curr Top Med Chem | 2011 | Acuña-Castroviejo D; López LC; Escames G; López A; García JA; Reiter RJ (2011) Melatonin-mitochondria interplay in health and disease. Curr Top Med Chem 11:221-240. |
Lopez 2009 J Pineal Res | 2009 | López A, García JA, Escames G, Venegas C, Ortiz F, López LC, Acuña-Castroviejo D (2009) Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production. J Pineal Res 46:188-98. |
Abstracts
Published | Reference | |
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Doerrier 2014 Abstract SECF | 2014 | Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice. |
Luna-Sánchez 2014 Abstract SECF | 2014 | Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment. |
Volt 2014 Abstract SECF | 2014 | Experimental basis for the “inflammaging” theory. |
Garcia 2014 Abstract SECF | 2014 | Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor. |
Diaz-Casado 2014 Abstract SECF | 2014 | Melatonin restores mitochondrial regulatory gene expression and function in the zebrafish model of parkinsonism. |
Volt 2014 Abstract The 2014 Ageing Summit | 2014 | Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis. |
Doerrier 2012 Abstract Bioblast | 2012 | Doerrier C, Garcia JA, Escames G, Acuna-Castroviejo D (2012) Treatment with melatonin prevents myocardial mitochondrial dysfunction in experimental sepsis in mice. Mitochondr Physiol Network 17.12. |