P50: Difference between revisions
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|description='''''p''<sub>50</sub>''' is the oxygen partial pressure at which (a) respiratory flux is 50% of maximum oxygen flux, [[Jmax|''J''<sub>max</sub>]], at saturating oxygen levels. The oxygen affinity is indirectly proportional to the ''p''<sub>50</sub>. The ''p''<sub>50</sub> depends on metabolic state and rate. (b) ''p''<sub>50</sub> is the oxygen partial pressure at which oxygen binding (on myoglobin, haemoglobin) is 50%, or desaturation is 50%. | |description='''''p''<sub>50</sub>''' is the oxygen partial pressure at which (a) respiratory flux is 50% of maximum oxygen flux, [[Jmax|''J''<sub>max</sub>]], at saturating oxygen levels. The oxygen affinity is indirectly proportional to the ''p''<sub>50</sub>. The ''p''<sub>50</sub> depends on metabolic state and rate. (b) ''p''<sub>50</sub> is the oxygen partial pressure at which oxygen binding (on myoglobin, haemoglobin) is 50%, or desaturation is 50%. | ||
|info=[[Gnaiger 1998 J Exp Biol]] | |info=[[Gnaiger 1998 J Exp Biol]] | ||
}} | |||
{{MitoPedia concepts | |||
|mitopedia concept=Respiratory state | |||
}} | }} | ||
{{MitoPedia methods | {{MitoPedia methods | ||
|mitopedia method=Respirometry, Spectrophotometry | |mitopedia method=Respirometry, Spectrophotometry | ||
}} | }} | ||
{{MitoPedia O2k and high-resolution respirometry}} | |||
{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic= | |mitopedia topic=Substrate and metabolite | ||
}} | }} |
Revision as of 15:02, 8 February 2016
Description
p50 is the oxygen partial pressure at which (a) respiratory flux is 50% of maximum oxygen flux, Jmax, at saturating oxygen levels. The oxygen affinity is indirectly proportional to the p50. The p50 depends on metabolic state and rate. (b) p50 is the oxygen partial pressure at which oxygen binding (on myoglobin, haemoglobin) is 50%, or desaturation is 50%.
Abbreviation: p50
Reference: Gnaiger 1998 J Exp Biol
MitoPedia concepts:
Respiratory state
MitoPedia methods:
Respirometry,
Spectrophotometry
MitoPedia topics: Substrate and metabolite