Difference between revisions of "Oxygen flux"
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{{MitoPedia | {{MitoPedia | ||
|abbr=''J''<sub>O2</sub> | |abbr=''J''<sub>O2</sub> | ||
|description='''Oxygen flux''', ''J''<sub>O<sub>2</sub></sub>, is a [[specific quantity]]. Oxygen [[flux]] is [[oxygen flow]], ''I''<sub>O<sub>2</sub></sub> [mol·s<sup>-1</sup> per system] (an [[extensive quantity]]), divided by system size. Flux may be volume-specific (flow per volume [pmol·s<sup>-1</sup>·mL<sup>-1</sup>]), mass-specific (flow per mass [pmol·s<sup>-1</sup>·mg<sup>-1</sup>]), or marker-specific (flow per mtEU). Oxygen flux (''e.g.'', per body mass, or per cell | |description='''Oxygen flux''', ''J''<sub>O<sub>2</sub></sub>, is a [[specific quantity]]. Oxygen [[flux]] is [[oxygen flow]], ''I''<sub>O<sub>2</sub></sub> [mol·s<sup>-1</sup> per system] (an [[extensive quantity]]), divided by system size. Flux may be volume-specific (flow per volume [pmol·s<sup>-1</sup>·mL<sup>-1</sup>]), mass-specific (flow per mass [pmol·s<sup>-1</sup>·mg<sup>-1</sup>]), or marker-specific (flow per mtEU). Oxygen flux (''e.g.'', per body mass, or per cell volume) is distinguished from oxygen flow (per number of objects, such as cells), ''I''<sub>O<sub>2</sub></sub> [mol·s<sup>-1</sup>·x<sup>-1</sup>]. These are different forms of [[normalization of rate]]. | ||
|info=[[ | |info=[[BEC 2020.1]], [[Gnaiger 2020 BEC MitoPathways]], [[Gnaiger 1993 Pure Appl Chem]], [[Renner 2003 Biochim Biophys Acta]] | ||
}} | }} | ||
Contributed by [[Gnaiger E]] (2020-01-15) | |||
== Which SI units should be used? == | == Which SI units should be used? == | ||
::::* Convert volume-specific oxygen flux, ''J''<sub>O<sub>2</sub></sub>, to units [nmol·s<sup>-1</sup>·L<sup>-1</sup>] = [pmol·s<sup>-1</sup>·mL<sup>-1</sup>] | :::* '''The SI unit for volume''' | ||
:::::: 1000 L = 1 m<sup>3</sup> | |||
:::::: 1 L = 1 dm<sup>3</sup> | |||
:::::: 1 mL = 1 cm<sup>3</sup> | |||
:::::: 1 µL = 1 mm<sup>3</sup> | |||
:::* '''Convert various units of volume-specific oxygen flux''', ''J''<sub>O<sub>2</sub></sub>, to '''SI units''' [nmol·s<sup>-1</sup>·L<sup>-1</sup>] = [pmol·s<sup>-1</sup>·mL<sup>-1</sup>] | |||
:::::: 1 µmol O<sub>2</sub>∙min<sup>-1</sup> ∙ 16.67 | :::::: 1 µmol O<sub>2</sub>∙min<sup>-1</sup>∙L<sup>-1</sup> ∙ [1000 nmol∙(1 µmol)<sup>-1</sup>] ∙ [1 min∙(60 s)<sup>-1</sup>] = 16.67 nmol O<sub>2</sub>∙s<sup>-1</sup>∙L<sup>-1</sup> | ||
:::::: 1 nmol O<sub>2</sub>∙min<sup>-1</sup> ∙ 16.67 | :::::: 1 nmol O<sub>2</sub>∙min<sup>-1</sup>∙mL<sup>-1</sup> ∙ [1000 pmol∙(1 nmol)<sup>-1</sup>] ∙ [1 min∙(60 s)<sup>-1</sup>] = 16.67 pmol O<sub>2</sub>∙s<sup>-1</sup>∙mL<sup>-1</sup> | ||
:::::: 1 nmol O<sub>2</sub>∙h<sup>-1</sup> ∙ 0.2778 | :::::: 1 nmol O<sub>2</sub>∙h<sup>-1</sup>∙mL<sup>-1</sup> ∙ [1000 pmol∙(1 nmol)<sup>-1</sup>] ∙ [1 min∙(60 s)<sup>-1</sup>] ∙ [1 h∙(60 min)<sup>-1</sup>] = 0.2778 pmol O<sub>2</sub>∙s<sup>-1</sup>∙mL<sup>-1</sup> | ||
:::::: 1 natom O∙s<sup>-1</sup> ∙ 0.5 | :::::: 1 natom O∙s<sup>-1</sup>∙L<sup>-1</sup> ∙ [1 nmol O<sub>2</sub>∙(2 natm O)<sup>-1</sup>] = 0.5 nmol O<sub>2</sub>∙s<sup>-1</sup>∙L<sup>-1</sup> | ||
:::::: 1 natom O∙min<sup>-1</sup> ∙ 8.33 | :::::: 1 natom O∙min<sup>-1</sup>∙L<sup>-1</sup> ∙ [1000 pmol O<sub>2</sub>∙(2 natom O)<sup>-1</sup>] ∙ [1 min∙(60 s)<sup>-1</sup>] = 8.33 pmol O<sub>2</sub>∙s<sup>-1</sup>∙L<sup>-1</sup> | ||
:::::: 1 mL O<sub>2</sub>∙min<sup>-1</sup> (at [[STPD]]) = | :::* '''Convert [[VO2max |''V''<sub>O<sub>2</sub>max/''M''</sub>]] from ergometric to SI units''' | ||
:::::: 1 mL O<sub>2</sub>∙min<sup>-1</sup>∙kg<sup>-1</sup> (at [[STPD]]) ∙ [1000 µmol∙(22.392 mL)<sup>-1</sup>] ∙ [1 min∙(60 s)<sup>-1</sup>] = 0.744 µmol O<sub>2</sub>∙s<sup>-1</sup>∙kg<sup>-1</sup> | |||
:::* There is a difference between '''oxygen flux per volume''' and '''oxygen concentration change per time''' | |||
:::::: The oxygen concentration change per time (=rate of concentration change) is expressed in units [µmol O<sub>2</sub>∙L<sup>-1</sup>∙s<sup>-1</sup>]. | :::::: The oxygen concentration change per time (= rate of concentration change) is expressed in units [µmol O<sub>2</sub>∙L<sup>-1</sup>∙s<sup>-1</sup>]. | ||
:::::::: By definition the rate of concentration change is zero in an open system at steady-state, when the concentration in the system does not change at any respiratory flux by the sample enclosed in the open system. | :::::::: By definition the rate of concentration change is zero in an open system at steady-state, when the concentration in the system does not change at any respiratory flux by the sample enclosed in the open system. | ||
:::::: Oxygen flux per volume (=volume-specific oxygen flux) is expressed in units [µmol O<sub>2</sub>∙s<sup>-1</sup>∙L<sup>-1</sup>] or [nmol O<sub>2</sub>∙s<sup>-1</sup>∙L<sup>-1</sup>] | :::::: Oxygen flux per volume (= volume-specific oxygen flux) is expressed in units [µmol O<sub>2</sub>∙s<sup>-1</sup>∙L<sup>-1</sup>] or [nmol O<sub>2</sub>∙s<sup>-1</sup>∙L<sup>-1</sup>] | ||
:::::::: By definition the volume-specific oxygen flux is the [[advancement]] of reaction per volume of the reaction chamber. | :::::::: By definition the volume-specific oxygen flux is the [[advancement]] of reaction per volume of the reaction chamber. | ||
:::::: Oxygen flux per mass (=mass-specific oxygen flux) is expressed in units [µmol O<sub>2</sub>∙s<sup>-1</sup>∙kg<sup>-1</sup>] = [pmol O<sub>2</sub>∙s<sup>-1</sup>∙mg<sup>-1</sup>] | :::::: Oxygen flux per mass (= mass-specific oxygen flux) is expressed in units [µmol O<sub>2</sub>∙s<sup>-1</sup>∙kg<sup>-1</sup>] = [pmol O<sub>2</sub>∙s<sup>-1</sup>∙mg<sup>-1</sup>] | ||
:::::::: By definition the mass-specific oxygen flux is the [[advancement]] of reaction per mass of the sample enclosed in the reaction chamber. | :::::::: By definition the mass-specific oxygen flux is the [[advancement]] of reaction per mass of the sample enclosed in the reaction chamber. | ||
== References == | |||
{{#ask:[[Additional label::Oxygen flux]] | |||
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{{Template:Keywords: Normalization}} | |||
{{MitoPedia concepts | {{MitoPedia concepts |
Latest revision as of 01:14, 31 December 2020
Description
Oxygen flux, JO2, is a specific quantity. Oxygen flux is oxygen flow, IO2 [mol·s-1 per system] (an extensive quantity), divided by system size. Flux may be volume-specific (flow per volume [pmol·s-1·mL-1]), mass-specific (flow per mass [pmol·s-1·mg-1]), or marker-specific (flow per mtEU). Oxygen flux (e.g., per body mass, or per cell volume) is distinguished from oxygen flow (per number of objects, such as cells), IO2 [mol·s-1·x-1]. These are different forms of normalization of rate.
Abbreviation: JO2
Reference: BEC 2020.1, Gnaiger 2020 BEC MitoPathways, Gnaiger 1993 Pure Appl Chem, Renner 2003 Biochim Biophys Acta
Contributed by Gnaiger E (2020-01-15)
Which SI units should be used?
- The SI unit for volume
- 1000 L = 1 m3
- 1 L = 1 dm3
- 1 mL = 1 cm3
- 1 µL = 1 mm3
- Convert various units of volume-specific oxygen flux, JO2, to SI units [nmol·s-1·L-1] = [pmol·s-1·mL-1]
- 1 µmol O2∙min-1∙L-1 ∙ [1000 nmol∙(1 µmol)-1] ∙ [1 min∙(60 s)-1] = 16.67 nmol O2∙s-1∙L-1
- 1 nmol O2∙min-1∙mL-1 ∙ [1000 pmol∙(1 nmol)-1] ∙ [1 min∙(60 s)-1] = 16.67 pmol O2∙s-1∙mL-1
- 1 nmol O2∙h-1∙mL-1 ∙ [1000 pmol∙(1 nmol)-1] ∙ [1 min∙(60 s)-1] ∙ [1 h∙(60 min)-1] = 0.2778 pmol O2∙s-1∙mL-1
- 1 natom O∙s-1∙L-1 ∙ [1 nmol O2∙(2 natm O)-1] = 0.5 nmol O2∙s-1∙L-1
- 1 natom O∙min-1∙L-1 ∙ [1000 pmol O2∙(2 natom O)-1] ∙ [1 min∙(60 s)-1] = 8.33 pmol O2∙s-1∙L-1
- There is a difference between oxygen flux per volume and oxygen concentration change per time
- The oxygen concentration change per time (= rate of concentration change) is expressed in units [µmol O2∙L-1∙s-1].
- By definition the rate of concentration change is zero in an open system at steady-state, when the concentration in the system does not change at any respiratory flux by the sample enclosed in the open system.
- The oxygen concentration change per time (= rate of concentration change) is expressed in units [µmol O2∙L-1∙s-1].
- Oxygen flux per volume (= volume-specific oxygen flux) is expressed in units [µmol O2∙s-1∙L-1] or [nmol O2∙s-1∙L-1]
- By definition the volume-specific oxygen flux is the advancement of reaction per volume of the reaction chamber.
- Oxygen flux per volume (= volume-specific oxygen flux) is expressed in units [µmol O2∙s-1∙L-1] or [nmol O2∙s-1∙L-1]
- Oxygen flux per mass (= mass-specific oxygen flux) is expressed in units [µmol O2∙s-1∙kg-1] = [pmol O2∙s-1∙mg-1]
- By definition the mass-specific oxygen flux is the advancement of reaction per mass of the sample enclosed in the reaction chamber.
- Oxygen flux per mass (= mass-specific oxygen flux) is expressed in units [µmol O2∙s-1∙kg-1] = [pmol O2∙s-1∙mg-1]
References
Bioblast link | Reference | Year |
---|---|---|
BEC 2020.1 doi10.26124bec2020-0001.v1 | Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 | 2020 |
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