Difference between revisions of "Iglesias-Gonzalez 2014 PhD Thesis"
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{{Labeling | {{Labeling | ||
|area=Respiration, Patients | |area=Respiration, Patients | ||
|organism= | |diseases=Parkinson's | ||
|organism=Rat | |||
|tissues=Nervous system | |tissues=Nervous system | ||
|preparations=Isolated mitochondria | |preparations=Isolated mitochondria | ||
|couplingstates=LEAK, OXPHOS, ET | |||
|couplingstates=LEAK, OXPHOS, | |pathways=N, S, NS, ROX | ||
| | |instruments=Oxygraph-2k, Theory | ||
|instruments=Oxygraph-2k | |||
}} | }} |
Latest revision as of 13:01, 5 August 2018
Iglesias-Gonzalez J (2014) Neurotoxicity induced by oxidative stress and aluminium in relation to Parkinson’s disease: a mitochondrial bioenergetic approach by high-resolution respirometry. PhD Thesis 1-242. |
Iglesias-Gonzalez J (2014) PhD Thesis
Abstract: The study of mitochondria during the last years has revealed that this organelle plays an important role in the development and onset of neurodegenerative disorders such as Parkinson's disease. The main hallmarks found in post‐mortem studies remark the importance of brain free radicals levels, the alteration in brain metabolic parameters and the presence of xenobiotics like metals for the neurodegenerative processes. Also, any energetic deficit related with the metabolic impairment due to an exposition to toxics or an...
Labels: MiParea: Respiration, Patients
Pathology: Parkinson's
Organism: Rat Tissue;cell: Nervous system Preparation: Isolated mitochondria
Coupling state: LEAK, OXPHOS, ET
Pathway: N, S, NS, ROX
HRR: Oxygraph-2k, Theory