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Holzner 2019 MitoFit Preprint Arch EA - Revision history
2024-03-29T12:38:42Z
Revision history for this page on the wiki
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https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=235133&oldid=prev
Gnaiger Erich at 06:29, 8 January 2023
2023-01-08T06:29:14Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 06:29, 8 January 2023</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|year=2019<del style="font-weight: bold; text-decoration: none;">-06-11</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|year=2019</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|abstract=Version 1 ('''v1''') '''2019-06-11''' [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf doi:10.26124/mitofit:ea19.MiPSchool.0004]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|abstract=Version 1 ('''v1''') '''2019-06-11''' [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf doi:10.26124/mitofit:ea19.MiPSchool.0004]</div></td></tr>
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=228347&oldid=prev
Gnaiger Erich at 14:49, 4 June 2022
2022-06-04T14:49:11Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Publication</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Publication</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. <del style="font-weight: bold; text-decoration: none;">MitoFit Preprint Arch [[</del>doi<del style="font-weight: bold; text-decoration: none;">:</del>10.26124/mitofit:ea19.MiPSchool.0004<del style="font-weight: bold; text-decoration: none;">]].</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. <ins style="font-weight: bold; text-decoration: none;">https://</ins>doi<ins style="font-weight: bold; text-decoration: none;">.org/</ins>10.26124/mitofit:ea19.MiPSchool.0004</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|info=[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic but not oxidative skeletal muscle in mice after one month of high fat high sucrose feeding]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|info=<ins style="font-weight: bold; text-decoration: none;">MitoFit Preprint Arch EA19.4. </ins>[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic but not oxidative skeletal muscle in mice after one month of high fat high sucrose feeding]</div></td></tr>
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=219939&oldid=prev
Gnaiger Erich at 02:05, 24 August 2021
2021-08-24T02:05:22Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0004]].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0004]].</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|info=[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] <del style="font-weight: bold; text-decoration: none;"> <big><big>'''</del>[http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic but not oxidative skeletal muscle in mice after one month of high fat high sucrose feeding]<del style="font-weight: bold; text-decoration: none;">'''</big></big></del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|info=[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic but not oxidative skeletal muscle in mice after one month of high fat high sucrose feeding]</div></td></tr>
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Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=211371&oldid=prev
Gnaiger Erich at 15:32, 30 November 2020
2020-11-30T15:32:46Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 15:32, 30 November 2020</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:::# Warren BE, Lou PH, Lucchinetti E, Zhang L, Clanachan AS, Affolter A, Hersberger M, Zaugg M, Lemieux H (2014), "Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat," Am J Physiol Endocrinol Metab, 306(6):658-67</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:::# Warren BE, Lou PH, Lucchinetti E, Zhang L, Clanachan AS, Affolter A, Hersberger M, Zaugg M, Lemieux H (2014), "Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat," Am J Physiol Endocrinol Metab, 306(6):658-67</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:::# Horscroft JA, O'Brien KA, Clark AD, Lindsay RT, Steel AS, Procter NEK, Devaux J, Frenneaux M, Harridge SDR, Murray AJ (2019) "Inorganic nitrate, hypoxia, and the regulation of cardiac mitochondrial respiration—probing the role of PPARα," FASEB J, 33</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>:::# Horscroft JA, O'Brien KA, Clark AD, Lindsay RT, Steel AS, Procter NEK, Devaux J, Frenneaux M, Harridge SDR, Murray AJ (2019) "Inorganic nitrate, hypoxia, and the regulation of cardiac mitochondrial respiration—probing the role of PPARα," FASEB J, 33</div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Event ==</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">::::» [[MiPschool Coimbra 2019]]</ins></div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Preprints for [[Gentle Science]] ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Preprints for [[Gentle Science]] ==</div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|additional=Preprints</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|additional=Preprints</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr>
</table>
Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=211284&oldid=prev
Gnaiger Erich at 12:04, 30 November 2020
2020-11-30T12:04:02Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:04, 30 November 2020</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|year=2019</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|year=2019<ins style="font-weight: bold; text-decoration: none;">-06-11</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|journal=MitoFit Preprint Arch</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|journal=MitoFit Preprint Arch</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|abstract=Version 1 ('''v1''') '''2019-06-11''' [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf doi:10.26124/mitofit:ea19.MiPSchool.0004]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|abstract=Version 1 ('''v1''') '''2019-06-11''' [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf doi:10.26124/mitofit:ea19.MiPSchool.0004]</div></td></tr>
</table>
Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=180861&oldid=prev
Iglesias-Gonzalez Javier at 07:39, 19 June 2019
2019-06-19T07:39:48Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:39, 19 June 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l10">Line 10:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|abstract=Version 1 ('''v1''') '''2019-06-11''' [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf doi:10.26124/mitofit:ea19.MiPSchool.0004]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|abstract=Version 1 ('''v1''') '''2019-06-11''' [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf doi:10.26124/mitofit:ea19.MiPSchool.0004]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Rates of obesity and the metabolic syndrome, which are strongly associated with type 2 diabetes (T2D) and cardiovascular disease, continue to rise worldwide. Skeletal muscle is an important tissue in the development of these disorders, as it serves as the major “glucose sink” in the body, and skeletal muscle mitochondrial dysfunction occurs in both metabolic syndrome and T2D [1]. Understanding of the early processes involved in skeletal muscle dysfunction, including changes in mitochondrial function, is currently lacking. It has been proposed that greater mitochondrial oxidation capacity, as is the case in oxidative muscles such as the soleus, can allay the onset of mitochondrial dysfunction induced by high fat, high sugar (HFHS) feeding. Previous studies in fructose fed rats appear to support this view [2]. If this is the case, soleus muscle may be less likely to develop mitochondrial dysfunction than a more glycolytic muscle, such as the gastrocnemius, when exposed to short term HFHS feeding. Here we investigated effect of HFHS feeding over one month on skeletal muscle oxidative capacity, comparing respiration in soleus and gastrocnemius fibres.keywords=</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Rates of obesity and the metabolic syndrome, which are strongly associated with type 2 diabetes (T2D) and cardiovascular disease, continue to rise worldwide. Skeletal muscle is an important tissue in the development of these disorders, as it serves as the major “glucose sink” in the body, and skeletal muscle mitochondrial dysfunction occurs in both metabolic syndrome and T2D [1]. Understanding of the early processes involved in skeletal muscle dysfunction, including changes in mitochondrial function, is currently lacking. It has been proposed that greater mitochondrial oxidation capacity, as is the case in oxidative muscles such as the soleus, can allay the onset of mitochondrial dysfunction induced by high fat, high sugar (HFHS) feeding. Previous studies in fructose fed rats appear to support this view [2]. If this is the case, soleus muscle may be less likely to develop mitochondrial dysfunction than a more glycolytic muscle, such as the gastrocnemius, when exposed to short term HFHS feeding. Here we investigated effect of HFHS feeding over one month on skeletal muscle oxidative capacity, comparing respiration in soleus and gastrocnemius fibres.</div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|</ins>keywords=<ins style="font-weight: bold; text-decoration: none;">[[Diabetes]] & [https://wiki.oroboros.at/index.php/O2k-Publications:_Skeletal_muscle| Skeletal muscle]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|editor=[[Iglesias-Gonzalez J]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|editor=[[Iglesias-Gonzalez J]]</div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|mipnetlab=[[UK Cambridge Murray AJ]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Affiliations ==</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Holzner Lorenz MW(1), Sowton AP(2), Murray AJ(1)</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">::::# Institute of Metabolic Science, Metabolic Research Laboratories, University of Cambridge - lmwh2@cam.ac.uk</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">::::# Department of Physiology, Development and Neuroscience, University of Cambridge</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Results ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Results ==</div></td></tr>
</table>
Iglesias-Gonzalez Javier
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=180367&oldid=prev
Gnaiger Erich at 07:16, 12 June 2019
2019-06-12T07:16:55Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 07:16, 12 June 2019</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0004]].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0004]].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|info=[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] <big><big>'''[http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic but not oxidative skeletal muscle in mice after one month of high fat high sucrose feeding]'''</big></big></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|info=[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] <big><big>'''[http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic but not oxidative skeletal muscle in mice after one month of high fat high sucrose feeding]'''</big></big></div></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><br /></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><br /></div></td></tr>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|year=2019</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|year=2019</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|journal=MitoFit Preprint Arch</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|journal=MitoFit Preprint Arch</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|abstract=Rates of obesity and the metabolic syndrome, which are strongly associated with type 2 diabetes (T2D) and cardiovascular disease, continue to rise worldwide. Skeletal muscle is an important tissue in the development of these disorders, as it serves as the major “glucose sink” in the body, and skeletal muscle mitochondrial dysfunction occurs in both metabolic syndrome and T2D [1]. Understanding of the early processes involved in skeletal muscle dysfunction, including changes in mitochondrial function, is currently lacking. It has been proposed that greater mitochondrial oxidation capacity, as is the case in oxidative muscles such as the soleus, can allay the onset of mitochondrial dysfunction induced by high fat, high sugar (HFHS) feeding. Previous studies in fructose fed rats appear to support this view [2]. If this is the case, soleus muscle may be less likely to develop mitochondrial dysfunction than a more glycolytic muscle, such as the gastrocnemius, when exposed to short term HFHS feeding. Here we investigated effect of HFHS feeding over one month on skeletal muscle oxidative capacity, comparing respiration in soleus and gastrocnemius fibres.keywords=</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|abstract=<ins style="font-weight: bold; text-decoration: none;">Version 1 ('''v1''') '''2019-06-11''' [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf doi:10.26124/mitofit:ea19.MiPSchool.0004]</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Rates of obesity and the metabolic syndrome, which are strongly associated with type 2 diabetes (T2D) and cardiovascular disease, continue to rise worldwide. Skeletal muscle is an important tissue in the development of these disorders, as it serves as the major “glucose sink” in the body, and skeletal muscle mitochondrial dysfunction occurs in both metabolic syndrome and T2D [1]. Understanding of the early processes involved in skeletal muscle dysfunction, including changes in mitochondrial function, is currently lacking. It has been proposed that greater mitochondrial oxidation capacity, as is the case in oxidative muscles such as the soleus, can allay the onset of mitochondrial dysfunction induced by high fat, high sugar (HFHS) feeding. Previous studies in fructose fed rats appear to support this view [2]. If this is the case, soleus muscle may be less likely to develop mitochondrial dysfunction than a more glycolytic muscle, such as the gastrocnemius, when exposed to short term HFHS feeding. Here we investigated effect of HFHS feeding over one month on skeletal muscle oxidative capacity, comparing respiration in soleus and gastrocnemius fibres.keywords=</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|editor=[[Iglesias-Gonzalez J]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|editor=[[Iglesias-Gonzalez J]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>}}</div></td></tr>
</table>
Gnaiger Erich
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=180350&oldid=prev
Iglesias-Gonzalez Javier at 16:00, 11 June 2019
2019-06-11T16:00:36Z
<p></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 16:00, 11 June 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l2">Line 2:</td>
<td colspan="2" class="diff-lineno">Line 2:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Publication</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Publication</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0004]].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0004]].</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>|info=[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] <big></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>|info=[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] <big><big>'''[<ins style="font-weight: bold; text-decoration: none;">http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10</ins>.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic but not oxidative skeletal muscle in mice after one month of high fat high sucrose feeding]'''</big></big></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><big>'''[<del style="font-weight: bold; text-decoration: none;">Holzner 2019 MitoFit Preprint Arch doi 10</del>.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic<del style="font-weight: bold; text-decoration: none;">, </del>but not oxidative skeletal muscle in mice after one month of high fat<del style="font-weight: bold; text-decoration: none;">, </del>high sucrose feeding]'''</big></big></div></td><td colspan="2"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><br /></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><br /></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><br /></div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div><br /></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </div></td></tr>
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<td colspan="2" class="diff-lineno">Line 16:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Results ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Results ==</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">:[[File:Holzner 2019 MitoFit Preprint Arch EA Figure 1.png]]</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">:[[File:Holzner 2019 MitoFit Preprint Arch EA Figure 2.png]]</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== References ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== References ==</div></td></tr>
</table>
Iglesias-Gonzalez Javier
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=180347&oldid=prev
Iglesias-Gonzalez Javier at 15:53, 11 June 2019
2019-06-11T15:53:47Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 15:53, 11 June 2019</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">TEstttttttttttttttt</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{MitoFit page name}}</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{Publication</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|title=Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0004]].</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|info=[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] <big></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><big>'''[Holzner 2019 MitoFit Preprint Arch doi 10.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding]'''</big></big></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><br /></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><br /></ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|authors=Holzner Lorenz MW, Sowton AP, Murray AJ </ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|year=2019</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|journal=MitoFit Preprint Arch</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|abstract=Rates of obesity and the metabolic syndrome, which are strongly associated with type 2 diabetes (T2D) and cardiovascular disease, continue to rise worldwide. Skeletal muscle is an important tissue in the development of these disorders, as it serves as the major “glucose sink” in the body, and skeletal muscle mitochondrial dysfunction occurs in both metabolic syndrome and T2D [1]. Understanding of the early processes involved in skeletal muscle dysfunction, including changes in mitochondrial function, is currently lacking. It has been proposed that greater mitochondrial oxidation capacity, as is the case in oxidative muscles such as the soleus, can allay the onset of mitochondrial dysfunction induced by high fat, high sugar (HFHS) feeding. Previous studies in fructose fed rats appear to support this view [2]. If this is the case, soleus muscle may be less likely to develop mitochondrial dysfunction than a more glycolytic muscle, such as the gastrocnemius, when exposed to short term HFHS feeding. Here we investigated effect of HFHS feeding over one month on skeletal muscle oxidative capacity, comparing respiration in soleus and gastrocnemius fibres.keywords=</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|editor=[[Iglesias-Gonzalez J]]</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">}}</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Results ==</ins></div></td></tr>
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<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== References ==</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">:::# Thyfault JP, Kraus RM, Hickner RC, Howell AW, Wolfe RR, Dohm GL (2004) "Impaired plasma fatty acid oxidation in extremely obese women," Am J Physiol Endocrinol Metab 287(6):1076-81</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">:::# Warren BE, Lou PH, Lucchinetti E, Zhang L, Clanachan AS, Affolter A, Hersberger M, Zaugg M, Lemieux H (2014), "Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat," Am J Physiol Endocrinol Metab, 306(6):658-67</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">:::# Horscroft JA, O'Brien KA, Clark AD, Lindsay RT, Steel AS, Procter NEK, Devaux J, Frenneaux M, Harridge SDR, Murray AJ (2019) "Inorganic nitrate, hypoxia, and the regulation of cardiac mitochondrial respiration—probing the role of PPARα," FASEB J, 33</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Preprints for [[Gentle Science]] ==</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{MitoFit preprint}}</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{Labeling</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">|additional=Preprints</ins></div></td></tr>
<tr><td colspan="2"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">}}</ins></div></td></tr>
</table>
Iglesias-Gonzalez Javier
https://wiki.oroboros.at/index.php?title=Holzner_2019_MitoFit_Preprint_Arch_EA&diff=180338&oldid=prev
Iglesias-Gonzalez Javier: Created page with "TEstttttttttttttttt"
2019-06-11T14:35:44Z
<p>Created page with "TEstttttttttttttttt"</p>
<p><b>New page</b></p><div>TEstttttttttttttttt</div>
Iglesias-Gonzalez Javier