Cerwenka 2016 Mol Cell Oncol: Difference between revisions
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{{Publication | {{Publication | ||
|title=Cerwenka A, Kopitz J, Schirmacher P, Roth W, Gdynia G (2016) HMGB1: The metabolic weapon in the arsenal of NK cells. Mol Cell Oncol 3:e1175538. | |title=Cerwenka A, Kopitz J, Schirmacher P, Roth W, Gdynia G (2016) HMGB1: The metabolic weapon in the arsenal of NK cells. Mol Cell Oncol 3:e1175538. | ||
|info=[https://www.ncbi.nlm.nih.gov/pubmed/27652323 PMID: 27652323] | |info=[https://www.ncbi.nlm.nih.gov/pubmed/27652323 PMID: 27652323] | ||
|authors=Cerwenka A, Kopitz J, Schirmacher P, Roth W, Gdynia G | |authors=Cerwenka A, Kopitz J, Schirmacher P, Roth W, Gdynia G | ||
|year=2016 | |year=2016 | ||
|journal=Mol Cell Oncol | |journal=Mol Cell Oncol | ||
|abstract=Targeting tumor glycolysis would hit the main energy source of cancer. We show that natural killer (NK) cells pursue this strategy by employing high mobility group box 1 (HMGB1) protein-a well-known proinflammatory cytokine-to specifically target glycolysis in cancer cells. This opens up new perspectives for cancer immunotherapy. | |abstract=Targeting tumor glycolysis would hit the main energy source of cancer. We show that natural killer (NK) cells pursue this strategy by employing high mobility group box 1 (HMGB1) protein-a well-known proinflammatory cytokine-to specifically target glycolysis in cancer cells. This opens up new perspectives for cancer immunotherapy. | ||
|keywords=Cancer, HMGB1, NK cells, Natural killer cells, Cell death, Immunotherapy, Innate immunity, Metabolism | |keywords=Cancer, HMGB1, NK cells, Natural killer cells, Cell death, Immunotherapy, Innate immunity, Metabolism | ||
}} | }} | ||
Revision as of 15:37, 28 November 2016
| Cerwenka A, Kopitz J, Schirmacher P, Roth W, Gdynia G (2016) HMGB1: The metabolic weapon in the arsenal of NK cells. Mol Cell Oncol 3:e1175538. |
Cerwenka A, Kopitz J, Schirmacher P, Roth W, Gdynia G (2016) Mol Cell Oncol
Abstract: Targeting tumor glycolysis would hit the main energy source of cancer. We show that natural killer (NK) cells pursue this strategy by employing high mobility group box 1 (HMGB1) protein-a well-known proinflammatory cytokine-to specifically target glycolysis in cancer cells. This opens up new perspectives for cancer immunotherapy. • Keywords: Cancer, HMGB1, NK cells, Natural killer cells, Cell death, Immunotherapy, Innate immunity, Metabolism
Labels: MiParea: Respiration
Pathology: Cancer
Tissue;cell: Endothelial;epithelial;mesothelial cell
HRR: Oxygraph-2k
Labels, 2016-11
