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Holzner 2019 MitoFit Preprint Arch EA
Additional label Preprints  +
Has abstract Version 1 ('''v1''') '''2019-06-11''' [htt
Version 1 ('''v1''') '''2019-06-11''' [http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf doi:10.26124/mitofit:ea19.MiPSchool.0004] Rates of obesity and the metabolic syndrome, which are strongly associated with type 2 diabetes (T2D) and cardiovascular disease, continue to rise worldwide. Skeletal muscle is an important tissue in the development of these disorders, as it serves as the major “glucose sink” in the body, and skeletal muscle mitochondrial dysfunction occurs in both metabolic syndrome and T2D [1]. Understanding of the early processes involved in skeletal muscle dysfunction, including changes in mitochondrial function, is currently lacking. It has been proposed that greater mitochondrial oxidation capacity, as is the case in oxidative muscles such as the soleus, can allay the onset of mitochondrial dysfunction induced by high fat, high sugar (HFHS) feeding. Previous studies in fructose fed rats appear to support this view [2]. If this is the case, soleus muscle may be less likely to develop mitochondrial dysfunction than a more glycolytic muscle, such as the gastrocnemius, when exposed to short term HFHS feeding. Here we investigated effect of HFHS feeding over one month on skeletal muscle oxidative capacity, comparing respiration in soleus and gastrocnemius fibres.keywords=
soleus and gastrocnemius fibres.keywords=  +
Has editor [[Iglesias-Gonzalez J]]  +
Has info [[File:MitoFit Preprint Arch pdf.png|left|
[[File:MitoFit Preprint Arch pdf.png|left|160px|link=http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf|MitoFit pdf]] <big><big>'''[http://www.mitofit.org/images/6/65/Holzner_2019_MitoFit_Preprint_Arch_doi_10.26124mitofit.ea19.MiPSchool.0004.pdf Evidence of altered mitochondrial function in glycolytic but not oxidative skeletal muscle in mice after one month of high fat high sucrose feeding]'''</big></big> <br />
g]'''</big></big> <br />  +
Has title Holzner Lorenz MW, Sowton AP, Murray AJ (2
Holzner Lorenz MW, Sowton AP, Murray AJ (2019) Evidence of altered mitochondrial function in glycolytic, but not oxidative skeletal muscle in mice after one month of high fat, high sucrose feeding. MitoFit Preprint Arch [[doi:10.26124/mitofit:ea19.MiPSchool.0004]].
oi:10.26124/mitofit:ea19.MiPSchool.0004]].  +
Was published in journal MitoFit Preprint Arch +
Was published in year 2019  +
Was written by Holzner Lorenz MW + , Sowton AP + , Murray AJ +
Display title of
"Display title of" is a predefined property that can assign a distinct display title to an entity and is provided by Semantic MediaWiki.
Holzner 2019 MitoFit Preprint Arch EA  +
Categories MitoFit , Publications
Modification date
"Modification date" is a predefined property that corresponds to the date of the last modification of a subject and is provided by Semantic MediaWiki.
07:16:55, 12 June 2019  +
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